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Retinal OCTA as a Window into Cerebral Small Vessel Disease and Cognitive Decline Post-Stroke
Neurologycognitive impairmentstroke

Retinal OCTA as a Window into Cerebral Small Vessel Disease and Cognitive Decline Post-Stroke

By MedXY|Sep 21, 2026

This longitudinal study shows that retinal microvascular changes measured by OCTA correspond with cerebral small vessel disease progression and cognitive decline in mild ischemic stroke patients, highlighting OCTA’s potential as a non

Prognostic Factors and Role of Allo-HSCT in First Salvage Therapy for Adults with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Blinatumomab and Inotuzumab Ozogamicin
Hematology-OncologyAllo-HSCT

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news6829 articlesCardiology1403 articlesClinical Updates1315 articlesOncology1176 articlesDiabetes & Endocrinology868 articlesNeurology834 articlesPublic Health605 articlesGastroenterology586 articles
MRD

Prognostic Factors and Role of Allo-HSCT in First Salvage Therapy for Adults with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Blinatumomab and Inotuzumab Ozogamicin

By MedXY|Sep 21, 2026

Early measurable residual disease (MRD) negativity and timing of relapse are crucial for risk stratification in adults with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) treated with blinatumomab and/or inotuzumab ozogamic

Distinct Weaning Phenotypes in Invasive Mechanical Ventilation Failures: Insights from the WEAN SAFE Cohort
Critical Carecritical caremechanical ventilation

Distinct Weaning Phenotypes in Invasive Mechanical Ventilation Failures: Insights from the WEAN SAFE Cohort

By MedXY|Sep 21, 2026

This study identifies three distinct phenotypes among patients failing to wean from invasive mechanical ventilation, linking failed initial attempts, withdrawal decisions, and mortality, highlighting the need for tailored management strateg

Low-Dose Ketamine Reduces Opioid Requirements in Mechanically Ventilated ICU Patients: Insights from a Double-Blind Randomized Trial
AnesthesiologyKetaminemechanical ventilation

Low-Dose Ketamine Reduces Opioid Requirements in Mechanically Ventilated ICU Patients: Insights from a Double-Blind Randomized Trial

By MedXY|Sep 21, 2026

A randomized controlled trial demonstrates that adjunct low-dose ketamine infusion safely decreases opioid use in mechanically ventilated adults without increasing delirium or adverse events, suggesting potential benefits in ICU analgosedat

Enabling Driving Resumption in ICU Survivors: Insights from a Comprehensive Driving Assessment Study
Critical Carecritical illnessfunctional recovery

Enabling Driving Resumption in ICU Survivors: Insights from a Comprehensive Driving Assessment Study

By MedXY|Sep 21, 2026

This study evaluates driving ability and resumption in adult ICU survivors after critical illness, identifying impairments and demonstrating that targeted interventions enable many to safely resume driving, enhancing post-ICU functional rec

Defining Diagnostic Excellence and Missed Diagnostic Opportunity in the Emergency Department: Key Consensus Recommendations for Practice and Research
Emergency Medicinediagnostic excellencemissed diagnostic opportunity

Defining Diagnostic Excellence and Missed Diagnostic Opportunity in the Emergency Department: Key Consensus Recommendations for Practice and Research

By MedXY|Sep 21, 2026

A multidisciplinary RAND/UCLA consensus defines ‘diagnostic excellence’ and ‘missed diagnostic opportunity’ for emergency departments, offering clear conceptual components to guide measurement, research, and quality

Dexmedetomidine Continuous Infusion to Maintain Sedation in Severely Agitated Adolescents in the Emergency Department: A Case Series Report
Emergency Medicinecase reportAdolescent Psychiatry

Dexmedetomidine Continuous Infusion to Maintain Sedation in Severely Agitated Adolescents in the Emergency Department: A Case Series Report

By MedXY|Sep 21, 2026

This report describes the use of dexmedetomidine infusion for sedation in severely agitated adolescents in the ED, highlighting its feasibility as a bridge therapy while awaiting psychiatric care.

Innovative Clinical Research Training for Medical Undergraduates: Enhancing Competency through Authentic Mentorship and Practice
Internal MedicineY học dựa trên bằng chứngmedical undergraduates

Innovative Clinical Research Training for Medical Undergraduates: Enhancing Competency through Authentic Mentorship and Practice

By MedXY|Sep 21, 2026

A novel educational model embedding clinical research training within real-world trials improves medical students’ research skills, fosters evidence-based thinking, and bridges clinical and academic integration.

Enhancing Interprofessional Teamwork in ICU: Developing Entrustable Professional Activities for Trainees and Advanced Practice Providers
Critical CareEntrustable Professional ActivitiesAdvanced Practice Providers

Enhancing Interprofessional Teamwork in ICU: Developing Entrustable Professional Activities for Trainees and Advanced Practice Providers

By MedXY|Sep 21, 2026

This article discusses the design and evaluation of entrustable professional activities (EPAs) promoting effective teamwork and psychological safety among trainees and advanced practice providers in ICU settings.

Ethics and Professionalism in AI and Medical Practice: Key Guidance from the American College of Physicians (2026 Position Paper)
AIAI ethicsphysician responsibility

Ethics and Professionalism in AI and Medical Practice: Key Guidance from the American College of Physicians (2026 Position Paper)

By MedXY|Sep 21, 2026

The ACP’s 2026 position paper offers clinician-focused ethical guidance for AI use in medicine, emphasizing relationality, self-governance, and competence to safeguard patient welfare, equity, transparency, and clinical judgment.

A Synopsis of the 2025 VA/DoD Lipid Management Guideline: What Clinicians Need to Know
Cardiologycardiovascular risklipids

A Synopsis of the 2025 VA/DoD Lipid Management Guideline: What Clinicians Need to Know

By MedXY|Sep 19, 2026

Concise review of the 2025 VA/DoD lipid guideline: new risk tool (PREVENT), CAC and one-time Lp(a) for risk refinement, statins for selected primary prevention groups (including people with HIV), and intensified combination therapy for very

Contemporary Outcomes of Autologous Stem Cell Transplantation in AL Amyloidosis: Insights from a Decade-Long Multicenter Study
Hematology-Oncologysurvival outcomesAL淀粉样变性

Contemporary Outcomes of Autologous Stem Cell Transplantation in AL Amyloidosis: Insights from a Decade-Long Multicenter Study

By MedXY|Sep 21, 2026

A multicenter retrospective study of 1047 AL amyloidosis patients undergoing autologous stem cell transplantation (2010–2020) demonstrates improved safety, deep hematologic responses, and durable survival, affirming ASCT’s vital role in tre

Age, Anthracycline Use, and Mortality Outcomes in Classic Hodgkin Lymphoma: Insights from a Large Complete Population Cohort
Clinical Updatesagechemotherapy

Age, Anthracycline Use, and Mortality Outcomes in Classic Hodgkin Lymphoma: Insights from a Large Complete Population Cohort

By MedXY|Sep 21, 2026

This review analyzes the impact of age and anthracycline-based chemotherapy on mortality in 28,000 classic Hodgkin lymphoma patients, highlighting poorer outcomes in the elderly and the therapeutic nuances influencing survival.

CPX-351 versus CLAG-M in Medically Unfit Adults with AML: A Phase 2 Randomized Study Evaluating Survival and Response Outcomes
Hematology-Oncologyphase 2 trialsurvival

CPX-351 versus CLAG-M in Medically Unfit Adults with AML: A Phase 2 Randomized Study Evaluating Survival and Response Outcomes

By MedXY|Sep 21, 2026

This phase 2 trial compares CPX-351 with CLAG-M chemotherapy in medically unfit adults with AML, finding CLAG-M achieves better 3-month survival and response rates, especially in patients with proliferative disease, suggesting intensive the

Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling
Hematology-OncologyBrain Injurysickle cell disease

Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling

By MedXY|Sep 21, 2026

This study identifies systemic pathological pathways that mediate blood-brain barrier injury in sickle cell disease, linking BBB disruption to brain hypoxia and microstructural injury, highlighting new therapeutic targets to preserve neurol

Integrin αIIbβ3 Deficiency Impairs Platelet Formation Through Serine Metabolic Dysregulation in Megakaryocytes
Hematology-OncologyGlanzmann thrombastheniaintegrin αIIbβ3

Integrin αIIbβ3 Deficiency Impairs Platelet Formation Through Serine Metabolic Dysregulation in Megakaryocytes

By MedXY|Sep 21, 2026

This study reveals that integrin αIIbβ3 deficiency in megakaryocytes disrupts serine metabolism, leading to reduced platelet production and shedding light on the complex pathophysiology underlying Glanzmann thrombasthenia.

Impact of Hospital Transfer-In Prevalence on Risk-Adjusted Outcomes: Insights from a National Retrospective Cohort Study
Clinical Updateshealth services researchRisk Adjustment

Impact of Hospital Transfer-In Prevalence on Risk-Adjusted Outcomes: Insights from a National Retrospective Cohort Study

By MedXY|Sep 21, 2026

This review synthesizes evidence on how hospitals’ prevalence of transfer-in patients relates to risk-adjusted mortality, length of stay, and charges, highlighting complex interplay between patient case mix and hospital performance me

Brain Natriuretic Peptide Levels as a Prognostic Biomarker After Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension
CardiologyprognosisBrain Natriuretic Peptide

Brain Natriuretic Peptide Levels as a Prognostic Biomarker After Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension

By MedXY|Sep 21, 2026

This study demonstrates that elevated brain natriuretic peptide (BNP) post-pulmonary endarterectomy strongly predicts mortality in chronic thromboembolic pulmonary hypertension (CTEPH), providing valuable prognostic information beyond persi

Evaluating High Intensity Interval Training Versus Moderate Intensity Continuous Training in Fibrotic Interstitial Lung Disease: Insights from a Randomized Controlled Trial
newspulmonary rehabilitationBệnh phổi mô kẽ

Evaluating High Intensity Interval Training Versus Moderate Intensity Continuous Training in Fibrotic Interstitial Lung Disease: Insights from a Randomized Controlled Trial

By MedXY|Sep 21, 2026

A randomized trial compared high intensity interval training (HIIT) with standard moderate intensity continuous training (MICT) in fibrotic interstitial lung disease, finding no superiority of HIIT but confirming its safety and feasibility.

GLP-1 Receptor Agonists and the Prevention of Obstructive Sleep Apnea in Type 2 Diabetes: Insights from a Large UK Cohort Study
Diabetes & Endocrinologycohort studyDPP‑4 inhibitors

GLP-1 Receptor Agonists and the Prevention of Obstructive Sleep Apnea in Type 2 Diabetes: Insights from a Large UK Cohort Study

By MedXY|Sep 19, 2026

A comprehensive UK cohort study shows that GLP-1 receptor agonists do not reduce the incidence of obstructive sleep apnea compared to DPP-4 inhibitors in obese patients with type 2 diabetes.

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