Radiology
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CT Small-Artery Loss Tracks Severe Pulmonary Hypertension in COPD and Fibrosing ILD More Closely Than Parenchymal Damage
CT-derived pulmonary vascular metrics, especially the small-artery to total arterial volume ratio, identify severe pulmonary hypertension in chronic lung disease, with distinct vascular remodeling patterns in COPD and fibrosing ILD.

Reduced Preoperative Radiotherapy to 36 Gy Maintains Excellent Long-Term Local Control in Myxoid Liposarcoma
Long-term phase 2 data suggest that 36 Gy preoperative radiotherapy for localized myxoid liposarcoma preserves excellent local control while limiting wound and late toxic effects.

Non-contrast abbreviated MRI shows superior accuracy to ultrasound for hepatocellular carcinoma surveillance in cirrhosis: interim prospective trial results
A prospective trial found that non-contrast abbreviated MRI detected hepatocellular carcinoma in cirrhotic patients far better than ultrasound, with most MRI-detected tumors found at an early, potentially curable stage.

Systemic Cardiovascular Factors and Outcomes in Dural Arteriovenous Fistulas: Insights From the CONDOR Registry
A large international registry study found that hemorrhage in dural arteriovenous fistulas is driven mainly by venous anatomy and lesion grade, not most cardiovascular comorbidities. Surgery was most associated with angiographic cure, and b

Advanced Liver Imaging Reveals Impaired Postprandial Hepatic Glucose Handling and Hidden Metabolic Subtypes in Type 1 Diabetes
A 7 T imaging and tracer study found that adults with type 1 diabetes have abnormal postprandial hepatic glucose uptake, blunted glycogen storage, reduced suppression of endogenous glucose production, and marked metabolic heterogeneity desp

Higher Amyloid PET Signal and Lower APOE ε4 Frequency Distinguish Iatrogenic From Sporadic Cerebral Amyloid Angiopathy
A single-center cross-sectional study found that iatrogenic cerebral amyloid angiopathy carries a higher amyloid PET burden, weaker CSF-PET coupling, and less APOE ε4 enrichment than sporadic disease, supporting a biologically distinct mech

Wider Cranial Arteries, Not Atherosclerotic Stenosis, Track With Lacunar Stroke and Cerebral Small-Vessel Disease
In a prospective mild stroke cohort, cranial arterial dolichoectasia and larger intracranial arterial diameters were linked to lacunar stroke, cSVD burden, and incident infarcts, whereas large-artery stenosis was not.

ACR TI-RADS Reduced Repeat Thyroid Ultrasound but Did Not Lower Biopsy or Surgery Rates in Real-World Practice
In a large single-center retrospective study, ACR TI-RADS implementation decreased follow-up thyroid ultrasound but did not reduce fine-needle aspiration, surgery, cancer yield, or overall costs.

AI-Driven Insights into Incidental Thyroid Findings: Prevalence, Clinical Impact, and the Overdiagnosis Dilemma
A retrospective cohort study using AI to analyze radiology reports reveals high prevalence of incidental thyroid findings, strong association with diagnostic cascades, and potential overdiagnosis of low-risk thyroid cancers.

68Ga-Pentixafor PET/CT Predicts Postoperative Outcomes in Primary Aldosteronism Surgery
68Ga-pentixafor PET/CT parameters correlate with clinical success post-adrenalectomy in primary aldosteronism, offering prognostic insights linked to histopathologic subtypes and CXCR4 expression.

Observation Reduces CT Use in Pediatric Blunt Abdominal Trauma Without Missing Critical Injuries
A multicenter study shows that observation with deferred CT decision-making significantly reduces CT use in children with blunt abdominal trauma, particularly in cases with intermediate clinician suspicion, without increasing missed injurie

Even the Largest Stroke Cores May Benefit from Thrombectomy, LASTE Ancillary Analysis Suggests
In patients aged under 80 with ASPECTS 0-2, endovascular thrombectomy improved disability outcomes and reduced mortality versus medical care alone, challenging the idea that very large infarcts should automatically exclude treatment.

Restrictive Thyroid Incidentaloma Guidelines Cut Workload Dramatically but Miss a Small Number of Low-Risk Cancers
Conventional imaging-detected thyroid incidentalomas rarely prove malignant. A retrospective study found restrictive guidelines can sharply reduce unnecessary workup, though a small number of low-risk cancers may be missed.

Early FDG-PET Predicts Survival Outcomes in Metastatic Breast Cancer: IMPACT-MBC Trial Reveals Rapid Response Imaging as a Powerful Prognostic Tool
The IMPACT-MBC trial demonstrates that performing FDG-PET after just 2 weeks of first-line systemic therapy can accurately identify metastatic breast cancer patients with distinct long-term outcomes, potentially improving treatment decision

WBC SPECT/CT Outperforms MRI in Early Detection of Diabetic Foot Osteomyelitis, Study Finds
A prospective study of 47 patients reveals that white blood cell SPECT/CT demonstrates superior sensitivity and specificity compared to conventional MRI for initial diagnosis of diabetic foot osteomyelitis. While both modalities perform equ

Normative Modeling Exposes Hidden Individual Variability in Traumatic Brain Injury: A New Frontier for Personalized Neuroimaging Assessment
A landmark study of 631 participants reveals that normative modeling uncovers substantial individual heterogeneity in brain morphology following traumatic brain injury that conventional group-based analyses miss, with every patient exhibiti

Basal Ganglia Perivascular Spaces: A Dual-Risk Biomarker for Ischemic Stroke and Major Bleeding in Antithrombotic Therapy
A large-scale prospective study identifies high basal ganglia perivascular space (BGPVS) burden as a significant predictor of both major bleeding and ischemic stroke in patients on antithrombotic regimens, offering a new imaging biomarker f

High Basal Ganglia Perivascular Space Burden Predicts Both Ischemic Stroke and Major Bleeding in Antithrombotic Users
A large prospective study reveals that a high burden of basal ganglia enlarged perivascular spaces (BGPVSs) significantly increases the risk of both ischemic stroke and major bleeding in patients on antithrombotic therapy, positioning BGPVS

Predictive Power of MRI-Based Radiomic Dynamics for Pathological Complete Response in Hepatocellular Carcinoma: A Deep Learning Synthesis
This review evaluates how deep learning-assisted delta radiomics on MRI, combined with AFP response, provides a non-invasive, high-accuracy prediction of pathological complete response in unresectable HCC undergoing conversion immunotherapy

Beyond Recanalization: Understanding the Dynamic Evolution of the No-Reflow Phenomenon After Stroke Thrombectomy
A prospective multicenter study reveals that the no-reflow phenomenon is a dynamic, evolving pathology following successful thrombectomy. It is significantly associated with infarct growth and poor functional outcomes, suggesting that achie
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