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A large Danish case-control study finds oral estrogen-containing therapies double the risk of incident porphyria cutanea tarda in women, highlighting the importance of administration route in risk assessment.
This study evaluates how surgical approach impacts survival and recurrence in low-risk cervical cancer, finding minimally invasive radical hysterectomy safe in low-risk patients but associated with poorer outcomes in high-risk groups.
Cluster analysis of physiological parameters in women with urgency urinary incontinence reveals three distinct phenotypes, offering insights for personalized treatment strategies.
This review synthesizes evidence from a rigorously conducted RCT demonstrating the efficacy and safety of nightly baclofen vaginal suppositories for chronic pelvic pain due to pelvic floor muscle dysfunction, highlighting therapeutic advanc
A randomized controlled trial shows that lower insufflation pressures during laparoscopic gynecologic surgery do not reduce postoperative pain but maintain adequate visualization, supporting individualized pressure use.
This review synthesizes evidence linking lifetime estrogen exposure—both endogenous and exogenous—with neurovascular integrity and Alzheimer’s disease risk in older women, highlighting the impact of reproductive lifespan and hormone t
From 2016 to 2022, gestational and pregestational diabetes prevalence rose alongside severe maternal morbidity in U.S. deliveries, with type 1 diabetes presenting the highest risk for severe complications.
Implementation of the HALT-C antenatal linkage-to-care bundle significantly increased hepatitis C treatment initiation and completion by six months postpartum, with majority of patients preferring antenatal therapy, demonstrating pregnancy
Cesarean delivery for the second twin after vaginal delivery of the first twin is linked to a threefold increase in severe neonatal morbidity and mortality. Key risk factors include absence of analgesia, transverse presentation, and low-vol
The MIRA2 trial demonstrates that adding a levonorgestrel-releasing intrauterine system immediately after endometrial ablation significantly reduces hysterectomy rates in women with heavy menstrual bleeding, without increasing serious adver
This article reviews a prospective study identifying subcutaneous adipose tissue (SAT) and smoking history, not BMI or physical fitness, as superior predictors of postoperative complications in DIEP flap breast reconstruction, enhancing ris
This review synthesizes evidence from randomized trials indicating that baseline lipid profiles significantly modify coronary heart disease risk associated with oral menopausal hormone therapy, underscoring the importance of lipid assessmen
This randomized trial demonstrates that periurethral estradiol cream application is noninferior to intravaginal application for preventing recurrent urinary tract infections in postmenopausal individuals, with comparable efficacy and improv
A landmark multicenter randomized trial reveals that first-line IVF yields higher live-birth rates than IUI with ovarian stimulation in unexplained infertility, with cumulative outcomes equalized after subsequent cycles.
This article reviews the Dallas Uterus Transplant Program’s rigorous living donor evaluation process, highlighting its critical role in optimizing donor safety and recipient success in uterus transplantation.
Analysis of anti-müllerian hormone (AMH) trajectories reveals two distinct decline patterns across menopause, with slower AMH decline linked to higher postmenopausal cardiovascular risk, independent of premenopausal risk factors.
Consistent resistance training combined with recommended aerobic activity and low sedentary television viewing substantially reduces major cardiovascular events risk in women, particularly myocardial infarction.
This review details the phase 3 PANKU-Breast01 trial evaluating izalontamab brengitecan versus chemotherapy in pretreated HR+/HER2- breast cancer, highlighting significant PFS improvement and safety considerations in a Chinese cohort.
Discontinuation of antidepressants during pregnancy is common and linked to increased mental health-related emergency visits, underscoring the need for supportive treatment strategies for perinatal mental health.
A large-scale analysis estimates the U.S. national burden of severe hemolytic disease of the fetus and newborn (HDFN) caused by anti-D, anti-K, and anti-c alloantibodies, revealing that severe HDFN is rare despite common alloimmunization.
