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Structural Brain Changes and Long-Term Outcomes in NMDA Receptor Encephalitis: Insights from a German Cross-Sectional Study
Neurologybrain morphologypsychiatric symptoms

Structural Brain Changes and Long-Term Outcomes in NMDA Receptor Encephalitis: Insights from a German Cross-Sectional Study

By MedXY|Sep 27, 2026

This study reveals persistent structural brain alterations and evolving psychiatric symptoms in post-acute NMDA receptor encephalitis, highlighting the need for focused long-term care and advanced imaging markers.

Atrial Mechanical Dysfunction as a Predictor of Stroke Risk in Transthyretin Amyloid Cardiomyopathy Patients in Sinus Rhythm
CardiologyAtrial mechanical contractionCerebrovascular risk

Atrial Mechanical Dysfunction as a Predictor of Stroke Risk in Transthyretin Amyloid Cardiomyopathy Patients in Sinus Rhythm

By MedXY|Sep 25, 2026

Left atrial mechanical dysfunction, particularly atrial electromechanical dissociation and impaired left atrial strain contraction, forecasts increased cerebrovascular events in transthyretin amyloid cardiomyopathy patients even in sinus rh

Enhancing Diagnosis of AQP4-IgG+ NMOSD Myelitis: The Role of Novel and Established Spinal MRI Signs
NeurologyNMOSDmyelitis

Enhancing Diagnosis of AQP4-IgG+ NMOSD Myelitis: The Role of Novel and Established Spinal MRI Signs

By MedXY|Sep 25, 2026

This article evaluates spinal MRI features in AQP4-IgG+ NMOSD myelitis, highlighting the diagnostic specificity of bright spotty lesions, the double-contoured LETM sign, and sagittal ring enhancement for differentiating NMOSD from other mye

Unveiling Brain Structural Changes in Bulimia Nervosa: Insights from the ENIGMA Consortium Analysis
NeurologyNeuroimagingbulimia nervosa

Unveiling Brain Structural Changes in Bulimia Nervosa: Insights from the ENIGMA Consortium Analysis

By MedXY|Sep 24, 2026

This large-scale meta-analysis identifies specific brain structural alterations—mainly in cortical surface area and subcortical volumes—associated with bulimia nervosa diagnosis and symptom severity, advancing understanding of its neurobiol

Epilepsy Risk Following Antipsychotic Use in Older Traumatic Brain Injury Survivors: Insights from a Population-Based Cohort Study
Clinical Updatespharmacoepidemiologypost-traumatic epilepsy

Epilepsy Risk Following Antipsychotic Use in Older Traumatic Brain Injury Survivors: Insights from a Population-Based Cohort Study

By MedXY|Sep 24, 2026

This review synthesizes evidence on the relationship between antipsychotic choice after traumatic brain injury (TBI) and post-traumatic epilepsy risk in older adults, highlighting recent population-based findings and mechanistic implication

Evaluating Sphenopalatine Ganglion Block Dosage for Headache Relief in the Emergency Department
Emergency Medicinesphenopalatine ganglion blockbupivacaine

Evaluating Sphenopalatine Ganglion Block Dosage for Headache Relief in the Emergency Department

By MedXY|Sep 24, 2026

This randomized trial found that larger doses of bupivacaine for sphenopalatine ganglion block did not improve sustained headache relief in emergency patients compared to smaller doses, with good tolerability across all doses.

Optimizing Etiologic Investigations After Status Epilepticus: Diagnostic Yield and Therapeutic Implications from the ICTAL Registry
Critical Carediagnostic yieldstatus epilepticus

Optimizing Etiologic Investigations After Status Epilepticus: Diagnostic Yield and Therapeutic Implications from the ICTAL Registry

By MedXY|Sep 23, 2026

Etiologic investigations after status epilepticus (SE) demonstrate variable diagnostic yield and significantly influence treatment decisions, especially when guided by clinical pretest probability. Tailored diagnostic strategies enhance tim

A Harmonized Visual Reading Framework for Tau PET Staging in Alzheimer Disease
Neurologytau PETcognitive impairment

A Harmonized Visual Reading Framework for Tau PET Staging in Alzheimer Disease

By MedXY|Sep 23, 2026

This study introduces a standardized 5-class framework for tau PET imaging to better detect and stage Alzheimer’s disease, improving early diagnosis and patient stratification across different tracers.

Identifying and Mitigating Risk Factors for Intracranial Haemorrhage Following Tenecteplase Fibrinolysis in Acute Myocardial Infarction
CardiologytenecteplaseRisk Prediction

Identifying and Mitigating Risk Factors for Intracranial Haemorrhage Following Tenecteplase Fibrinolysis in Acute Myocardial Infarction

By MedXY|Sep 23, 2026

This study evaluates risk factors for intracranial haemorrhage after tenecteplase fibrinolysis in STEMI patients, developing a prediction model highlighting age, blood pressure, sex, weight, and dose interactions as key determinants.

Temporal Dynamics and Morphological Predictors of Stroke Recurrence After Craniocervical Artery Dissection
NeurologyCraniocervical Artery DissectionDouble Lumen Sign

Temporal Dynamics and Morphological Predictors of Stroke Recurrence After Craniocervical Artery Dissection

By MedXY|Sep 22, 2026

This study delineates how vascular imaging morphologies, notably the double lumen sign, predict time-specific recurrence risk after craniocervical artery dissection, highlighting the hyperacute phase as critical for secondary prevention.

EEG Evolution and Seizure Characteristics in Early CDKL5 Deficiency Disorder: Implications for Developmental Outcomes
NeurologyEEGepileptic spasms

EEG Evolution and Seizure Characteristics in Early CDKL5 Deficiency Disorder: Implications for Developmental Outcomes

By MedXY|Sep 21, 2026

Longitudinal EEG analysis in infants with CDKL5 deficiency disorder reveals progressive background abnormalities and specific seizure phenotypes correlating with developmental severity within the first two years of life.

Long-Term Health Impacts of Military Blast Exposure on Veterans: Insights from the Millennium Cohort Study
NeurologyVeterans Healthoccupational risk

Long-Term Health Impacts of Military Blast Exposure on Veterans: Insights from the Millennium Cohort Study

By MedXY|Sep 21, 2026

This study reveals significant associations between high-level blast exposure during military service and increased risk for chronic health conditions in US Veterans, emphasizing the long-term occupational hazards of blast injuries.

Retinal OCTA as a Window into Cerebral Small Vessel Disease and Cognitive Decline Post-Stroke
Neurologycognitive impairmentstroke

Retinal OCTA as a Window into Cerebral Small Vessel Disease and Cognitive Decline Post-Stroke

By MedXY|Sep 21, 2026

This longitudinal study shows that retinal microvascular changes measured by OCTA correspond with cerebral small vessel disease progression and cognitive decline in mild ischemic stroke patients, highlighting OCTA’s potential as a non

Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling
Hematology-OncologyBrain Injurysickle cell disease

Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling

By MedXY|Sep 21, 2026

This study identifies systemic pathological pathways that mediate blood-brain barrier injury in sickle cell disease, linking BBB disruption to brain hypoxia and microstructural injury, highlighting new therapeutic targets to preserve neurol

Arterial Spin Labeling Hemodynamic Metrics Predict Cognitive Decline and Small Vessel Disease Progression Over 11 Years
NeurologyNeuroimagingarterial spin labeling

Arterial Spin Labeling Hemodynamic Metrics Predict Cognitive Decline and Small Vessel Disease Progression Over 11 Years

By MedXY|Sep 19, 2026

This study demonstrates that arterial spin labeling spatial coefficient of variation (ASL-sCoV) correlates with cerebral small vessel disease burden and predicts cognitive decline over 11 years, outperforming traditional cerebral blood flow

Inpatient Rehabilitation and Major Adverse Cardiovascular Events After Ischemic Stroke: Clinical Implications and Evidence Synthesis
Clinical Updatesmajor adverse cardiovascular eventsinpatient rehabilitation

Inpatient Rehabilitation and Major Adverse Cardiovascular Events After Ischemic Stroke: Clinical Implications and Evidence Synthesis

By MedXY|Sep 19, 2026

Postacute discharge to inpatient rehabilitation facilities (IRF) after acute ischemic stroke (AIS) is associated with a reduced 1-year risk of major adverse cardiovascular events (MACE) compared to discharge to home or skilled nursing facil

Emergent Interfacility Transfers for Ischemic Stroke in the U.S.: Patterns and Implications from 2016 to 2022
Emergency Medicinethrombectomyinterfacility transfer

Emergent Interfacility Transfers for Ischemic Stroke in the U.S.: Patterns and Implications from 2016 to 2022

By MedXY|Sep 19, 2026

This study analyzes national trends in emergent interfacility ischemic stroke transfers among Medicare beneficiaries, revealing shifts in transfer rates, patient characteristics, and hospital features associated with transferred versus nont

Harnessing Kynurenic Acid and the Gut-Brain Axis to Improve Stroke Recovery
GastroenterologyneuroprotectionKynurenic acid

Harnessing Kynurenic Acid and the Gut-Brain Axis to Improve Stroke Recovery

By MedXY|Sep 18, 2026

Kynurenic acid (KYNA) reduction in the gut correlates with worse poststroke outcomes. Supplementation activates a gut-brain neural circuit via GPR35 and the vagus nerve, promoting neuroprotection and functional recovery after ischemic strok

SGLT2 Inhibitors Enhance Recovery After Endovascular Thrombectomy in Diabetic Stroke Patients: A Multicenter Retrospective Study
Diabetes & Endocrinologydiabetic strokeSGLT2 inhibitors

SGLT2 Inhibitors Enhance Recovery After Endovascular Thrombectomy in Diabetic Stroke Patients: A Multicenter Retrospective Study

By MedXY|Sep 18, 2026

SGLT2 inhibitors administered after endovascular thrombectomy in diabetic stroke patients significantly improve 3-month functional outcomes, suggesting a promising adjunctive therapy for poststroke diabetes management.

Evaluating Stroke Risk in Asymptomatic Carotid Stenosis: Transcarotid Artery Revascularization versus Carotid Artery Stenting
CardiologyCarotid Artery StentingAsymptomatic Carotid Stenosis

Evaluating Stroke Risk in Asymptomatic Carotid Stenosis: Transcarotid Artery Revascularization versus Carotid Artery Stenting

By MedXY|Sep 17, 2026

This comparative analysis assesses ischemic stroke outcomes in patients with asymptomatic carotid stenosis undergoing transcarotid artery revascularization (TCAR) versus carotid artery stenting (CAS), highlighting no significant difference

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