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A 12-week trial demonstrated that memantine significantly improves cognitive function in adults with systemic lupus erythematosus experiencing neuropsychological dysfunction.
An international Delphi produced the first core outcome set (13 outcomes across five domains) and a 3‑level hierarchical composite endpoint for mechanical ventilation liberation trials in acute brain injury, enabling standardized reporting
This nationwide Finnish cohort study evaluates the competing risks of stroke, recurrent intracranial bleeding, and mortality with anticoagulation strategies in atrial fibrillation patients who had prior intracranial bleeding. It highlights
This study finds that older adults with poststroke mild cognitive impairment receiving combined physical and cognitive rehabilitation have a significantly reduced risk of progressing to dementia compared to physical rehabilitation alone.
The FULMA system introduces a single-camera, markerless motion capture technology to objectively assess upper limb motor function post-stroke, demonstrating promising accuracy aligned with clinical ratings and offering automated kinematic i
The 2024 McDonald criteria revisions enable earlier MS diagnosis in many patients with radiologically isolated syndrome (RIS), potentially altering management before clinical symptoms arise, according to a large multicenter Italian study.
This qualitative study explores how patients with Parkinson’s disease experience and perceive pain, revealing its complex impact on daily life and emotional well-being, underscoring the need for holistic pain management strategies.
This study reveals that LATE-NC, a common neuropathology in aging, is linked to cognitive impairment and coexisting brain lesions in a diverse Brazilian population, underscoring its significance beyond homogenous cohorts.
Immersive virtual reality-based naming therapy significantly improves language function, quality of life, and patient engagement in chronic post-stroke aphasia compared to conventional therapy.
This review synthesizes evidence linking lifetime estrogen exposure—both endogenous and exogenous—with neurovascular integrity and Alzheimer’s disease risk in older women, highlighting the impact of reproductive lifespan and hormone t
This study assesses the effectiveness of the V-FAST checklist in detecting visual impairments in suspected stroke patients compared to NIH Stroke Scale and orthoptist evaluation in an emergency setting.
Traumatic brain injury (TBI) compromises lung bacterial clearance by disrupting neutrophil function, increasing infection susceptibility as demonstrated in murine and porcine models and supported by human plasma studies.
Longitudinal plasma biomarkers p-tau217 and neurofilament light chain highlight α-synuclein pathology’s modulatory role in Alzheimer disease, identifying a distinct subgroup with accelerated neurodegeneration and potential for improved prog
This review synthesizes evidence on visual scanning training for post-stroke hemianopia, emphasizing the SEARCH trial’s economic evaluation alongside clinical outcomes and contextualizing with complementary rehabilitation strategies a
A comparative study reveals that cushioning the greater occipital nerve with a muscle flap during decompression surgery reduces reoperation rates compared to a fat flap, while both methods effectively relieve pain.
Delirium in hospitalized, cognitively normal adults significantly increases the risk of future mild cognitive impairment, dementia, and accelerates cognitive decline over years, highlighting the need for vigilant delirium prevention and mon
Athletes with ACL reconstruction show persistent neurocognitive deficits during decision-making under uncertainty, marked by altered cortical oscillatory dynamics that may increase reinjury risk, highlighting the need for neurocognitive ass
High-intensity locomotor training in chronic stroke patients induces significant strengthening and lateralization of the contralesional cortico-reticulospinal tract, correlating with improved walking capacity, elucidating new neuroplastic m
This study evaluates the shift from restrictive cardiopulmonary bypass (CPB) to criteria-based extracorporeal membrane oxygenation (ECMO) in lung transplantation, revealing a reduction in early major neurologic complications and ischemic st
This article reviews the clinical presentation, diagnostic challenges, and management strategies for cavernous sinus thrombosis (CST), emphasizing early diagnosis, imaging findings, and the critical role of sinus surgery and anticoagulation
