Section
Combining serum leucine-rich alpha-2-glycoprotein 1 (LRG-1) with citrulline offers a sensitive, noninvasive biomarker strategy for early detection and monitoring of rejection in intestinal transplantation, potentially reducing reliance on i
CaneStat, a recombinant hybrid protein, uniquely modulates enamel pellicle properties fostering increased resistance to early enamel erosion, as evidenced by biophysical and clinical assessments.
This study highlights the diagnostic value of endobronchial optical coherence tomography (EB-OCT) as a complementary, low-risk imaging modality that improves confidence and diagnostic accuracy in interstitial lung disease multidisciplinary
This article reviews a 13-year longitudinal study assessing blood-based biomarkers’ effectiveness in predicting all-cause dementia among community-dwelling older adults, highlighting their modest sensitivity and enhanced predictive value wh
This study reveals that six months of non-surgical periodontal therapy significantly modulates host and microbial extracellular vesicles in saliva, highlighting their potential as non-invasive biomarkers for monitoring periodontitis treatme
Raman spectroscopy-based urine molecular fingerprinting offers a promising non-invasive biomarker to predict delayed graft function, assess baseline kidney allograft quality, and monitor transplant health postoperatively in patients receivi
An expert-practice summary of the 2026 AASLD EXPO on liver biopsy: indications, techniques (percutaneous, transjugular, EUS-guided), sample adequacy, safety thresholds, and emerging applications including molecular profiling and digital pat
This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is
This review synthesizes evidence on racial and ethnic differences in plasma phosphorylated tau 217 (%p-tau217) in preclinical Alzheimer disease, highlighting implications for diagnostic screening and biomarker validity across diverse popula
This study reveals that ameloblastomas uniquely maintain primary cilia and exhibit CEP164 overexpression, highlighting a distinct molecular signature that may influence tumor behavior and offer new diagnostic and therapeutic avenues.
A novel deep learning model significantly improves diagnostic accuracy in distinguishing fibro-osseous jaw lesions (FD, COF, COD) from histology images, outperforming expert pathologists and offering a promising diagnostic support tool.
This pilot study demonstrates the feasibility and high diagnostic accuracy of the Histolog Scanner, an ultra-fast ex vivo confocal microscopy system, for intraoperative margin assessment in transoral laser microsurgery of glottic squamous c
This study uncovers molecular subtypes of salivary adenoid cystic carcinoma based on genomic and transcriptomic analyses, introducing a novel copy number variation (CNV)-based classification that improves prognostic accuracy and could refin
This study identifies immune biomarkers, including proliferative CD8+ T cells, CD68+ macrophages, and PD-1 expression, which differentiate high-risk oral tongue epithelial dysplasia and may improve patient risk stratification beyond convent
Plasma pTau217 levels measured by Lumipulse G assays strongly correlate with postmortem temporal cortex pTau217 pathology, supporting plasma pTau217 as a reliable biomarker for brain tau pathology in Alzheimer disease.
Early disclosure of plasma p-tau217 and NfL biomarkers significantly improves diagnostic confidence and clinical decisions in cognitive decline without increasing emotional distress, supporting their integration into routine memory clinic c
This review synthesizes evidence on clinical and biological factors linked to discordance between plasma p-tau217 and standard AD biomarkers, highlighting implications for diagnosis, patient stratification, and future biomarker development.
Core needle biopsy (CNB) demonstrates high diagnostic accuracy for major salivary gland tumors, offering a reliable tool to distinguish benign from malignant lesions and potentially reduce unnecessary surgeries.
This study delineates distinct clinical, radiographic, laboratory, and histopathologic features separating allergic fungal rhinosinusitis from eosinophilic chronic rhinosinusitis with nasal polyps in a Middle Eastern tertiary-care cohort.
TESERA leverages computational pathology to classify hepatocellular carcinoma into biologically distinct morphologic subtypes from standard H&E slides, offering accurate prognosis stratification competitive with clinical and molecular m
