Section
A large Danish case-control study finds oral estrogen-containing therapies double the risk of incident porphyria cutanea tarda in women, highlighting the importance of administration route in risk assessment.
This study assesses a novel biologic optimization strategy guided by the end-of-dose effect in partial responders with hidradenitis suppurativa, revealing meaningful clinical improvements and offering a framework for personalized treatment
Ruxolitinib cream demonstrates sustained safety and effective disease control over 52 weeks in children aged 2 to 11 years with mild-to-moderate atopic dermatitis, affirming its role as a promising therapeutic option.
This population-based study reveals significant differences in pathological response and survival outcomes between stage III melanoma patients with lymph node metastases and those with in-transit metastases treated with neoadjuvant PD-1 inh
A phase 1 study demonstrates that low-dose intralesional cemiplimab is safe and achieves high complete response rates in early-stage cutaneous squamous cell carcinoma, supporting further clinical exploration.
This article explores the pivotal role of Nicotinamide N-methyltransferase (NNMT) in fibroblast activation and extracellular matrix deposition driving skin fibrosis in systemic sclerosis, highlighting therapeutic potential of NNMT inhibitio
This study reveals a distinctive dual Th17/Th2 immune endotype and pronounced IL-36 activation in Taiwanese patients with psoriasis, highlighting the need for tailored therapeutic approaches in this ethnic group.
A multicenter Chinese study developed and externally validated the Psoriasis TB Risk Score (PTRS) to stratify psoriasis patients’ risk of high interferon-γ release assay (IGRA) responses before biologic treatment, facilitating tailore
Dupilumab treatment in children aged 6–11 with severe atopic dermatitis is associated with significant improvements in linear growth and bone biomarker levels over one year, suggesting benefits beyond skin clearance.
This study demonstrates that physiological concentration platelet fibrin plasma (PFP) is noninferior to supraphysiological platelet-rich plasma (PRP) in healing neuro-ischemic diabetic foot ulcers and other diabetic wounds, offering a simpl
This phase 2 randomized trial demonstrates that IL-4-receptor-α blockade with dupilumab significantly improves clinical outcomes and reduces fibrosis-associated inflammation and gene signatures in localised scleroderma, supporting a novel t
This study introduces a novel classification framework for systemic sclerosis based on vascular and fibrotic complications, identifying a high-risk mixed endotype with distinct immunologic features and prognostic relevance, offering improve
This study examines 417 retroauricular interpolated flap repairs after Mohs surgery, identifying stage-specific complication rates and risk factors such as diabetes and defect size to inform surgical risk management.
This review synthesizes evidence on the characteristic clinical and histopathologic features of condyloma lata in secondary syphilis, emphasizing its reliable recognition to prevent misdiagnosis, especially at extragenital sites.
This retrospective study evaluates the incidence and risk factors for infantile hemangioma ulceration following oral propranolol therapy, highlighting subtype-related risks and anatomical protective factors to guide clinical management.
In a randomized trial, sodium citrate as an anticoagulant in concentrated growth factor therapy for androgenetic alopecia reduced injection pain, improved hair density, and increased patient satisfaction compared with heparin sodium or no a
This large cohort study demonstrates that biologic therapy in pregnant women with psoriasis is not associated with increased adverse pregnancy outcomes and may reduce risks of spontaneous abortion and gestational diabetes.
A retrospective analysis reveals hematoporphyrin monomethyl ether-mediated photodynamic therapy (HMME-PDT) outperforms pulsed dye laser (PDL) in clearing facial and neck port-wine stains but with an increased risk of hyperpigmentation and s
This study quantifies the risk and identifies predictors for systemic lupus erythematosus development in children presenting with skin-limited discoid lupus erythematosus, highlighting the importance of early monitoring especially in patien
This exploratory trial compares cobratide injection and pregabalin for moderate-to-severe acute herpes zoster neuralgia, showing similar pain relief with better tolerability for cobratide and a potential reduction in postherpetic neuralgia
