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A thorough secondary analysis of a randomized clinical trial reveals no significant association between cornea donor diabetes severity and graft success, endothelial cell loss, or morphometric parameters at 1 year post-DMEK, supporting the
CDK4/6 inhibitor therapy in hormone receptor-positive breast cancer is linked to increased corneal epithelial alterations, including punctate epitheliopathy and vortex keratopathy, independent of aromatase inhibitor effects or tear film dys
Mitomycin C applied via injection or sponge during trabeculectomy offers comparable intraocular pressure control and safety, with injection potentially yielding more favorable bleb morphology and fewer postoperative interventions.
An open-label trial demonstrates the safety and potential efficacy of ChrimsonR-based optogenetic therapy combined with specialized goggles to enhance light sensitivity in patients with advanced retinitis pigmentosa, offering promising aven
PCSK9 inhibitors significantly reduce the risk of retinal vascular occlusions compared to other lipid-lowering therapies in patients with hyperlipidemia, highlighting their potential as a neuroprotective cardiovascular intervention.
This study reveals a significant increase in female representation among American Board of Ophthalmology oral board examiners following the transition to virtual exams, while the proportion of female examinees remained stable from 2011 to 2
The ELZA-sub400 protocol demonstrates safe and effective high-fluence corneal cross-linking tailored for ultrathin keratoconus corneas, halting ectasia progression in most treated eyes at 12 months with no endothelial damage.
This study compares retreatment rates and timing in retinopathy of prematurity among infants treated with intravitreal bevacizumab versus laser therapy, highlighting lower early retreatment rates and delayed intervention in the bevacizumab
This study elucidates the intricate three-dimensional morphology and cellular organization of outer retinal tubulation (ORT) in Bietti crystalline dystrophy, revealing structural reorganization of residual outer retina with potential implic
This randomized trial compares aflibercept monotherapy versus combined with reduced-fluence photodynamic therapy for PCV, highlighting OCTA metrics that predict polypoidal lesion closure and treatment response over 52 weeks.
Ultra-widefield swept-source OCT excels in assessing small-to-medium choroidal tumors, outperforming SD-OCT and providing detailed structural insights with noninvasive precision, though larger or complex tumors benefit from multimodal imagi
Ocular proton therapy in uveal melanoma induces significant reductions in corneal nerve parameters with partial recovery by 12 months, while corneal sensitivity remains stable and patient-reported symptoms show limited correlation with stru
This retrospective cohort study indicates that menopausal hormone therapy (MHT) is associated with increased risks of strabismus diagnosis and surgery but not reoperation in menopausal women, revealing significant ocular alignment considera
This study elucidates the dynamic nature and structural correlates of mid-phase hyperfluorescent plaques on ICGA in CSCR, highlighting their progression stages and OCT features that signal disease activity.
Ocular proton therapy causes significant decreases in corneal nerve fiber parameters in uveal melanoma patients, with partial recovery by 12 months and minimal changes in corneal sensitivity and patient-reported outcomes.
Early rapid optic nerve head swelling in NAION correlates with worse visual outcomes, with OCT measures of pONHV and mGCIPL thinning providing prognostic insights within days of symptom onset.
This review synthesizes longitudinal OCT findings and clinical outcomes in NAION, highlighting the prognostic value of early optic nerve head swelling rates for visual impairment progression, and discusses mechanistic and translational impl
Genetic analyses reveal that cholesteryl ester transfer protein (CETP) inhibition, while beneficial for cardiovascular disease, is associated with an increased risk of age-related macular degeneration (AMD) across European and East Asian po
Novel IOP metrics from remote home tonometry reflecting exceeding patient-specific IOP targets are significantly associated with visual field progression in treated open-angle glaucoma, outperforming conventional in-office measures.
This multicenter study of 305 eyes over 12 years reveals pathogen-specific clinical features and outcomes in culture-positive endogenous endophthalmitis, highlighting unique presentations, prognosis, and risks especially for gram-negative a
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