Section
This article reviews a study evaluating toothpastes containing bioadhesive polymers for their capacity to prevent enamel erosion and erosion-abrasion, highlighting polyacrylic acid formulations as promising agents.
This review synthesizes evidence from the DAPT-SHOCK-AMI trial and related studies comparing intravenous cangrelor to crushed oral ticagrelor in AMI complicated by cardiogenic shock, highlighting platelet inhibition efficacy, clinical outco
This multicenter retrospective study demonstrates that removing central venous catheters in pediatric cancer patients with Staphylococcus aureus bloodstream infections significantly reduces both short-term and late complications compared to
A 12-week trial demonstrated that memantine significantly improves cognitive function in adults with systemic lupus erythematosus experiencing neuropsychological dysfunction.
A large Danish case-control study finds oral estrogen-containing therapies double the risk of incident porphyria cutanea tarda in women, highlighting the importance of administration route in risk assessment.
A retrospective study demonstrates that a modified individualized tongue reconstruction technique using profunda artery perforator flaps significantly improves speech, swallowing, and aesthetics compared to conventional flap designs.
An international Delphi produced the first core outcome set (13 outcomes across five domains) and a 3‑level hierarchical composite endpoint for mechanical ventilation liberation trials in acute brain injury, enabling standardized reporting
Hospitalizations, cardiac testing, and revascularizations for chest pain patients without AMI have substantially declined from 2007 to 2021, without an increase in 180-day post-visit AMI risk overall, though older adults show modest rises.
This cohort study reveals a significant pandemic-induced decline in lung cancer screening among US Veterans, with delayed recovery and altered diagnosis patterns, highlighting critical implications for early detection and mortality outcomes
Upfront whole genome and transcriptome sequencing (WGTS) improves diagnostic yield in inherited bone marrow failure syndromes (IBMFS) by identifying diverse pathogenic variants and novel mechanisms, guiding personalized patient management a
The EMBARC-BRIDGE study reveals a distinct systemic neutrophil-endothelial inflammatory signature in bronchiectasis, closely linked to disease severity, lung function decline, and exacerbation risk, alongside altered neutrophil function.
This review synthesizes evidence highlighting national disparities in adult strabismus care access in the US, focusing on socioeconomic factors, insurance status, and practice types, and discusses implications for clinical practice and poli
This study analyzes the impact of elective neck dissection (END) on overall survival in patients with cT1-4 N0M0 submandibular gland cancer, revealing that despite a notable rate of occult nodal metastasis, END does not improve survival out
The ACS Emergency General Surgery Verification Program has demonstrated significant improvements in hospital length of stay, acute kidney injury, and 30-day mortality by driving standardized care and process enhancements in emergency surgic
This study evaluates how surgical approach impacts survival and recurrence in low-risk cervical cancer, finding minimally invasive radical hysterectomy safe in low-risk patients but associated with poorer outcomes in high-risk groups.
Myeloid cell CD36 deficiency reduces hepatic fibrosis by preventing macrophage ferroptosis and restoring antigen presentation, thereby enhancing CD8+ T cell-mediated adaptive immunity. This identifies CD36 as a promising therapeutic target
This nationwide Finnish cohort study evaluates the competing risks of stroke, recurrent intracranial bleeding, and mortality with anticoagulation strategies in atrial fibrillation patients who had prior intracranial bleeding. It highlights
In 585 RAS-mutated thyroid nodules, distinct molecular and clinical features predict malignancy risk and guide surgical management, with isolated RAS mutations showing low recurrence and potential for conservative care.
The DAPARHT trial demonstrates that dapagliflozin improves kidney function slope over 12 months in heart transplant recipients, offering a promising renal protective strategy without additional safety risks.
HB0025, a bispecific antibody targeting PD-L1 and VEGF pathways, combined with chemotherapy, demonstrated encouraging efficacy and manageable safety in advanced non-small cell lung cancer patients, supporting further phase 3 evaluation.
