Emergency Medicine
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Association Between Emergency Department Undertriage or Overtriage With Timeliness of Care and Patient Outcomes
A large multicenter study found that emergency department triage mismatches were linked to small delays in care and longer stays, especially for overtriaged patients. Better use of patient history may improve triage accuracy.

One in Six Older Emergency Department Patients Has Delirium: New Multisite Data Highlight Missed Risk, Mixed Management, and Higher Hospital Use
A large multisite cohort found delirium in 16% of older adults in the emergency department, including nearly 8% of those discharged, with strong links to dementia, acuity, hospitalization, and 30-day readmission.

One in Six Older Adults Presenting to the Emergency Department Had Delirium, With Higher Admission and 30-Day Readmission Risk
A large multi-site cohort found delirium in 16% of older ED patients, including many discharged home, and linked it to higher admission and 30-day readmission, underscoring the need for standardized screening and supportive care.

Extracorporeal CPR May Improve Survival After Pediatric Out-of-Hospital Cardiac Arrest, but Evidence Remains Early
A Japanese multicenter registry study suggests ECPR may improve 1-month survival and neurologic outcomes in selected children with out-of-hospital cardiac arrest, although estimates were imprecise and residual confounding remains a major li

Extracorporeal Cardiopulmonary Resuscitation for Pediatric Out-of-Hospital Cardiac Arrest
In selected children with out-of-hospital cardiac arrest, extracorporeal CPR was associated with higher one-month survival and better neurologic outcomes than continued conventional CPR, though the study was observational and estimates were

Clinical Care Guideline Implementation of Nebulized Tranexamic Acid in Post-Tonsillectomy Hemorrhage
A clinical care guideline improved emergency use of nebulized tranexamic acid for post-tonsillectomy bleeding and was associated with fewer returns to the operating room.

A Post-Tonsillectomy Hemorrhage Guideline Using Nebulized Tranexamic Acid Was Associated With Fewer Returns to the Operating Room
A quality-improvement clinical care guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage achieved high protocol adherence and was associated with a marked reduction in operative intervention.

Clinical Care Guideline Implementation of Nebulized Tranexamic Acid in Post-Tonsillectomy Hemorrhage
A clinical care guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage was rapidly adopted in the Emergency Department and was associated with fewer returns to the operating room.

A Clinical Care Guideline for Nebulized Tranexamic Acid Was Associated With Fewer Operating Room Returns After Post-Tonsillectomy Hemorrhage
A structured emergency department guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage achieved rapid protocol uptake and was associated with a marked reduction in operative hemorrhage control.

A Standardized Emergency Department Guideline for Nebulized Tranexamic Acid Was Linked to Fewer Operating Room Returns After Post-Tonsillectomy Hemorrhage
A hospital clinical care guideline enabled rapid uptake of nebulized tranexamic acid for eligible post-tonsillectomy hemorrhage and was associated with a marked reduction in operative control of bleeding.

A Post-Tonsillectomy Hemorrhage Guideline With Nebulized Tranexamic Acid Was Linked to Fewer Returns to the Operating Room
A quality-improvement guideline standardizing nebulized tranexamic acid for post-tonsillectomy hemorrhage achieved high protocol adherence and was associated with a marked reduction in operative hemorrhage control.

Digital Shared Decision Support Increased STI Testing for Adolescents and Young Adults in the Emergency Department
In a randomized controlled trial, the STIckER smartphone-based decision aid increased gonorrhea/chlamydia and pharyngeal STI testing in emergency department patients aged 14 to 24 years, while improving decisional clarity, satisfaction, and

An Emergency Department Nudge-Based Strategy to Screen and Treat Patients With Alcohol Misuse
A multicomponent emergency department workflow using screening, electronic prompts, and discharge decision support significantly increased naltrexone prescribing for patients with alcohol-related diagnoses.

Intravenous Magnesium Sulfate for Acute Nontraumatic Headache in the Emergency Department
Intravenous magnesium sulfate added to paracetamol increased early headache-treatment success in the emergency department, but the pain relief was modest and below usual clinical importance thresholds. It also reduced rescue analgesia needs

Unequal Paths to Care: How Region, Rurality, and Deprivation Shape Transport to Verified Trauma Centers Among the Critically Injured
A large U.S. study found major geographic and socioeconomic differences in how critically injured patients are transported to verified trauma centers, with outcomes varying by region, rurality, and neighborhood deprivation.

Associations of the Composite Pulmonary Embolism Shock Score in the Emergency Department With Short-Term Clinical Outcomes
A multicenter emergency department study found that CPES performed similarly to sPESI and ESC for short-term PE outcomes, but it better predicted the need for advanced intervention.

DISTAL at 12 Months: No Functional or Survival Advantage for Endovascular Therapy in Mild-to-Moderate Medium or Distal Vessel Occlusion Stroke
The DISTAL trial found no 12-month disability or survival benefit from adding endovascular treatment to best medical therapy in mild-to-moderate medium or distal vessel occlusion stroke.

Adjunct Intra-arterial Alteplase After Successful Basilar Thrombectomy Was Safe but Did Not Improve 90-Day Outcomes in IAT-TOP
In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between g

A New hs-cTnT Generation 6 Assay Matches Generation 5 for Myocardial Infarction Diagnosis While Labeling Fewer Patients as Myocardially Injured
In suspected myocardial infarction, hs-cTnT-gen6 showed diagnostic accuracy comparable to gen5, produced fewer myocardial injury classifications, and supported highly sensitive ESC 0/1-hour and 0/2-hour rule-out and rule-in pathways using a

TEE-Guided Chest Compression Targeting During ED Resuscitation Did Not Improve Clinical Outcomes in Out-of-Hospital Cardiac Arrest
In EXECT-CPR, transesophageal echocardiography-guided adjustment of compression site during emergency department CPR did not significantly improve ROSC or survival, despite signals of improved hemodynamics and no excess safety concerns.
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