Section
This cohort study reveals a significant pandemic-induced decline in lung cancer screening among US Veterans, with delayed recovery and altered diagnosis patterns, highlighting critical implications for early detection and mortality outcomes
The EMBARC-BRIDGE study reveals a distinct systemic neutrophil-endothelial inflammatory signature in bronchiectasis, closely linked to disease severity, lung function decline, and exacerbation risk, alongside altered neutrophil function.
HB0025, a bispecific antibody targeting PD-L1 and VEGF pathways, combined with chemotherapy, demonstrated encouraging efficacy and manageable safety in advanced non-small cell lung cancer patients, supporting further phase 3 evaluation.
Significant variability exists among US lung transplant centers in updating clinical data for candidates, potentially impacting allocation priority and transplant equity. Most variation remains unexplained by candidate or center characteris
A novel Pre-COPD score, integrating smoking history, symptoms, asthma, and spirometry, robustly predicts incident COPD across three multinational cohorts, enabling early risk stratification and preventive strategies in clinical practice.
A study using causal forest algorithms reveals heterogeneous benefits of high flow nasal oxygen in immunocompromised patients with acute respiratory failure, identifying subgroups who may significantly avoid invasive mechanical ventilation.
This article examines how pulse oximetry may under-detect sleep apnea events in Black individuals due to skin pigmentation-related measurement bias, highlighting heart-rate response as a reliable, pigmentation-independent marker predictive
A randomized controlled trial demonstrates that functional inspiratory muscle training integrated with resistance exercise improves functional capacity and respiratory muscle performance in individuals with obesity, complementing benefits f
A 9-year-old girl underwent right upper lobectomy for type 1 CPAM; postoperative right middle lobe displacement led to bronchial obstruction and persistent cough, highlighting rare complications after pediatric lobectomy.
Serum periostin measured one year after lung transplantation correlates with subsequent chronic lung allograft dysfunction, offering a promising biomarker for early risk stratification.
Airway occlusion maneuvers during noninvasive ventilation offer reliable, noninvasive measurements of inspiratory effort and lung mechanics, improving clinical monitoring in hypoxemic patients post-extubation.
The 2026 ATS guideline endorses as-needed inhaled corticosteroid (ICS)-containing reliever strategies across asthma severity to reduce severe exacerbations and harms from SABA-only treatment.
This study evaluates the shift from restrictive cardiopulmonary bypass (CPB) to criteria-based extracorporeal membrane oxygenation (ECMO) in lung transplantation, revealing a reduction in early major neurologic complications and ischemic st
Spatial proteomics reveals how EGFR and KRAS mutations distinctly remodel the immune microenvironment in non-small cell lung cancer, identifying immune niches and prognostic markers that may guide immunotherapy strategies.
This RCT explored music therapy’s role during invasive mechanical ventilation weaning in ICU patients, showing benefits in agitation reduction, sedation needs, and tracheostomy rates, though weaning duration was unaffected.
In patients with suspected obstructive sleep apnea, increased respiratory effort measured by negative esophageal pressure during sleep independently predicts long-term mortality beyond traditional markers, underscoring its clinical importan
Different cardiopulmonary exercise testing prediction equations yield widely variable percent-predicted values for peak oxygen uptake, leading to frequent reclassification of exercise performance influenced mainly by body mass index, age, a
The POWER trial assessed a self-directed lifestyle program for patients with OSA and obesity, finding modest improvements in sleep-related quality of life but limited clinically meaningful weight loss over 12 months.
The R-ALPS randomized trial confirms that benmelstobart improves progression-free survival in unresectable stage III NSCLC patients post-chemoradiotherapy, while adding anlotinib does not significantly enhance efficacy and raises severe tox
Tozorakimab, targeting interleukin-33, significantly reduces moderate to severe COPD exacerbations in former and current smokers despite standard inhaled therapy, offering a novel therapeutic approach with a favorable safety profile.
