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Macrophage circHIPK2 Silencing Reduces Post-Infarction Inflammation and Fibrosis and Improves Cardiac Recovery
A 2026 European Heart Journal study identifies macrophage circHIPK2 as a regulator of post-MI inflammation and fibrosis, with macrophage-targeted silencing improving cardiac remodeling in mice and showing translational promise in human myoc
Allergy & ImmunologyJun 10, 2026
EN
Macrophage circHIPK2 After Myocardial Infarction: A New RNA Node Linking Inflammation, Stress Granules, and Fibrotic Remodelling
A 2026 European Heart Journal study identifies macrophage circHIPK2 as a regulator of post-MI inflammation and fibrosis, integrating circular RNA biology with macrophage polarization, stress-granule signaling, and emerging immune-targeted R
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