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This review synthesizes recent randomized clinical trials and real-world studies confirming the safety and efficacy of highly aspherical lenslets (HAL) spectacle lenses in slowing myopia progression among children, emphasizing comparative e
Histidine-rich glycoprotein (HRG) directly modulates platelet adhesion and aggregation by binding platelet receptors GPIbα and GPIIb/IIIa, competing with key ligands VWF and fibrinogen, thus attenuating thrombus formation; reduced HRG in se
This review contrasts early- and late-phase gynecologic oncology trials, underscoring disparities in trial completion, publication, and racial/ethnic minority enrollment, highlighting the need to improve inclusivity and reporting.
Emerging evidence identifies KIF13B facilitating KPNA2-mediated nuclear import of PPARα as a critical mechanism to mitigate alcohol-associated liver steatosis, highlighting novel therapeutic strategies for ALD.
This review synthesizes evidence on colchicine’s efficacy in secondary stroke prevention, emphasizing the impact of concomitant atherosclerosis on outcomes from the CONVINCE trial and meta-analyses.
Serum neurofilament light chain (sNfL) z-score dynamics enhance monitoring of treatment response in relapsing multiple sclerosis (RMS), providing complementary predictive value for disease activity beyond conventional clinical and MRI asses
MedXY editors Abstract Video gaming should not be treated as a single health exposure. Conventional sedentary video games, cognitively oriented games,
Emerging evidence from prospective birth cohorts reveals a dose-dependent association between early respiratory infections and the risk of childhood atopic dermatitis, independent of genetic predisposition and antibiotic exposure.
This review synthesizes evidence from a pivotal randomized clinical trial and complementary literature on psychotherapeutic interventions addressing the psychological impact of killing in war, emphasizing improvements in PTSD, moral injury,
This review explores the Global Lymphoma Registry Alliance’s roadmap for leveraging multinational real-world data collaborations to address lymphoma’s heterogeneity, optimize treatment strategies, and improve patient outcomes worldwide thro
Autoimmune conditions in acute interstitial pneumonia (AIP) are associated with reduced 90-day mortality and better discharge outcomes, indicating distinct clinical trajectories and opportunities for tailored care.
Social vulnerability significantly elevates mortality and complications after major cardiac surgery, and treatment at high-volume centers does not mitigate these disparities, highlighting the need for systemic interventions beyond hospital
This review synthesizes recent evidence linking menopausal hormone therapy (MHT), particularly estrogen-only regimens, with decreased Alzheimer disease neuropathology and clinical dementia risk, highlighting biomarker correlations, clinical
This review synthesizes evidence on daily and weekly patterns of glycemic control in real-world CGM data, highlighting small but consistent temporal variations that inform personalized diabetes care.
Emerging evidence identifies circulating imidazole propionate, a gut microbiota-derived metabolite, as an independent predictor of major adverse cardiovascular events in patients with coronary artery disease, offering novel insights into pe
This review synthesizes nationwide epidemiological trends of sepsis in South Korea from 2011 to 2022, elucidating incidence increases, declining in-hospital mortality, and key clinical and socioeconomic mortality determinants alongside rele
The NEAT phase 3 trial evaluated erythrocyte-encapsulated dexamethasone sodium phosphate in children with ataxia telangiectasia aged 6–9 years, confirming safety but failing to demonstrate statistically significant neurological improvement
This review synthesizes evidence on the incidence and risk factors for progression within pachychoroid subtypes, highlighting diagnostic stability, factors predictive of neovascularization, and implications for clinical management.
Two large phase 3 trials demonstrated that upadacitinib significantly improves hair regrowth and quality of life in severe alopecia areata among adolescents and adults, with a consistent and manageable safety profile.
This review synthesizes evidence showing that Medicaid expansion under the Affordable Care Act significantly reduced 1-year mortality among young adults starting dialysis by improving insurance coverage and access to nephrology care.
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