Section
A decade-long multicentre Asian registry analysis revealed no significant difference in all-cause mortality between PCI with drug-eluting stents and CABG for unprotected left main coronary artery disease, highlighting the need for individua
A 9-year-old girl underwent right upper lobectomy for type 1 CPAM; postoperative right middle lobe displacement led to bronchial obstruction and persistent cough, highlighting rare complications after pediatric lobectomy.
This article explores the pivotal role of Nicotinamide N-methyltransferase (NNMT) in fibroblast activation and extracellular matrix deposition driving skin fibrosis in systemic sclerosis, highlighting therapeutic potential of NNMT inhibitio
Serum periostin measured one year after lung transplantation correlates with subsequent chronic lung allograft dysfunction, offering a promising biomarker for early risk stratification.
This study reveals a distinctive dual Th17/Th2 immune endotype and pronounced IL-36 activation in Taiwanese patients with psoriasis, highlighting the need for tailored therapeutic approaches in this ethnic group.
This study evaluates high-frequency ultrasound’s role in visualizing midline crossing-over vessels in DIEP flap breast reconstruction and finds no correlation between ultrasound-detected vessel characteristics and intraoperative flap
Traumatic brain injury (TBI) compromises lung bacterial clearance by disrupting neutrophil function, increasing infection susceptibility as demonstrated in murine and porcine models and supported by human plasma studies.
This study analyzes tracheal intubation success and safety among pediatric emergency trainees, revealing comparable performance between emergency medicine residents and PEM fellows, while highlighting lower success and higher adverse events
Participation in a structured behavioral health training program among primary care providers is linked to significantly lower mental health stigma, suggesting education as a key strategy to improve equitable mental health care.
A first-in-human study demonstrates that BCMA-targeted CAR T-cell therapy induces rapid, sustained platelet recovery and durable drug-free remission in refractory primary immune thrombocytopenia with manageable safety.
Airway occlusion maneuvers during noninvasive ventilation offer reliable, noninvasive measurements of inspiratory effort and lung mechanics, improving clinical monitoring in hypoxemic patients post-extubation.
This study establishes that 7 to 10 consecutive days of remote home tonometry are required to accurately capture intraocular pressure fluctuations, essential for effective glaucoma management.
This randomized controlled trial demonstrates that topical tranexamic acid effectively achieves initial hemostasis in acute spontaneous epistaxis, though it does not significantly reduce early rebleeding rates within 24 hours.
Metabolic bariatric surgery induces significant histologic regression of cirrhosis and fibrosis remodeling in patients with compensated metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis, challenging the notion that cirrhosis
Implementation of the HALT-C antenatal linkage-to-care bundle significantly increased hepatitis C treatment initiation and completion by six months postpartum, with majority of patients preferring antenatal therapy, demonstrating pregnancy
Aripiprazole, an atypical antipsychotic, shows promising chemopreventive effects against hepatocellular carcinoma (HCC) via antifibrotic, anti-inflammatory, and tumor-suppressive mechanisms involving liver fibroblasts, macrophages, and canc
Longitudinal plasma biomarkers p-tau217 and neurofilament light chain highlight α-synuclein pathology’s modulatory role in Alzheimer disease, identifying a distinct subgroup with accelerated neurodegeneration and potential for improved prog
This large international cohort study clarifies the clinical course, management strategies, and outcomes of ectopic Cushing syndrome, highlighting early biochemical remission as crucial for reducing mortality and complications.
The PREVENT-HF equations demonstrate excellent capability in predicting 10-year risk of heart failure, particularly for HFpEF, across diverse community and clinical samples, highlighting opportunities for subtype-specific risk stratificatio
This article examines the deep medial collateral ligament’s structural properties and failure characteristics, revealing its critical biomechanical role in knee stability and implications for surgical repair.
