Section
This article reviews a study on the impact of timing between postmastectomy radiotherapy and autologous breast reconstruction, highlighting no significant differences in complication rates across various intervals.
This review synthesizes evidence from the HPTN 094 trial assessing mobile integrated PrEP and MOUD services versus peer navigation for people who inject drugs, highlighting key outcomes, limitations, and implications for HIV prevention and
A study using causal forest algorithms reveals heterogeneous benefits of high flow nasal oxygen in immunocompromised patients with acute respiratory failure, identifying subgroups who may significantly avoid invasive mechanical ventilation.
This article reviews the development and preliminary evaluation of a novel toolkit designed to facilitate patient-centered decision-making in end-stage kidney disease, improving the implementation of the KDOQI End-Stage Kidney Disease Life
Recent evidence identifies USP22 as a key regulator of MEIS1 protein stability, revealing a promising therapeutic target to disrupt leukemogenic transcription in KMT2Ar acute leukemia.
This article examines how pulse oximetry may under-detect sleep apnea events in Black individuals due to skin pigmentation-related measurement bias, highlighting heart-rate response as a reliable, pigmentation-independent marker predictive
A large nationwide case-case-time-control study revealed intravenous bisphosphonates, especially zoledronic acid, are associated with a short-term increased risk of uveitis, with no clear links to scleritis or cystoid macular edema.
This study reveals that preoperative ultrasound frequently overestimates papillary thyroid carcinoma tumor size and has limited accuracy for detecting multifocality and extrathyroidal extension, suggesting caution in surgical decision-makin
VEGFA and EGF polymorphisms differentially affect cholangiocarcinoma susceptibility and postoperative survival, highlighting their potential as biomarkers for clinical stratification.
A randomized controlled trial shows that lower insufflation pressures during laparoscopic gynecologic surgery do not reduce postoperative pain but maintain adequate visualization, supporting individualized pressure use.
This study reveals how age and sex modulate liver transcriptomic responses to statin therapy in metabolic dysfunction-associated steatotic liver disease (MASLD), highlighting statins’ potential to suppress liver aging by targeting sen
This review synthesizes evidence linking lifetime estrogen exposure—both endogenous and exogenous—with neurovascular integrity and Alzheimer’s disease risk in older women, highlighting the impact of reproductive lifespan and hormone t
From 2016 to 2022, gestational and pregestational diabetes prevalence rose alongside severe maternal morbidity in U.S. deliveries, with type 1 diabetes presenting the highest risk for severe complications.
The SINGLE-CLOSURE trial demonstrated that single-ProGlide closure is noninferior to double-ProGlide closure in reducing vascular complications after transfemoral TAVR, offering a simpler alternative without increased risk.
Pudendal nerve palsy occurs frequently after hip arthroscopy using a perineal post, with symptoms commonly resolving by one year. Increased traction duration and force are significant risk factors, and persistent symptoms impair hip-specifi
A randomized controlled trial demonstrates that functional inspiratory muscle training integrated with resistance exercise improves functional capacity and respiratory muscle performance in individuals with obesity, complementing benefits f
This article explores a novel quantitative framework using nonlinear mixed effects modeling to improve characterization of oral pH dynamics, enhancing caries risk prediction and supporting clinical and translational research.
Plozasiran, targeting APOC3 mRNA, significantly lowers triglyceride levels and reduces acute pancreatitis incidence in severe hypertriglyceridemia patients, according to pooled data from two placebo-controlled trials.
This study assesses the effectiveness of the V-FAST checklist in detecting visual impairments in suspected stroke patients compared to NIH Stroke Scale and orthoptist evaluation in an emergency setting.
This article explores how the autotaxin/lysophosphatidic acid axis regulates macrophage-driven osteoclastogenesis and inflammation in periodontitis, highlighting the therapeutic potential of autotaxin inhibitors to prevent alveolar bone res
