500 articles · 20 / page
This article reviews a prospective study comparing Laser Speckle Contrast Imaging (LSCI) and Indocyanine Green (ICG) fluorescence for predicting necrosis in immediate breast reconstruction, highlighting LSCI’s repeatability and sensitivity
This review synthesizes evidence on individual and institutional factors linked to suspected suicide among higher-education students in England, highlighting risk profiles, service contact patterns, and shortcomings in investigation practic
Elevated plasma levels of H3.1 nucleosomes at ICU admission correlate with increased mortality and acute kidney injury requiring renal replacement therapy in sepsis, highlighting their potential as prognostic biomarkers.
This review synthesizes recent evidence on the effectiveness of 2024-2025 COVID-19 vaccines in adults, highlighting moderate protection against symptomatic illness, hospitalization, and critical outcomes, with emphasis on waning immunity an
The American College of Physicians’ 2026 position paper calls for comprehensive payer coverage, healthy food access, bias reduction, and research to tackle adult obesity through multisector public policy.
This study evaluates non-invasive biomarkers to differentiate essential thrombocythemia, premyelofibrosis, and overt myelofibrosis, revealing distinct inflammatory and immune profiles and supporting a disease continuum model.
The SwissLEGIO score refines Legionella prediction in community-acquired pneumonia, enhancing specificity while maintaining high sensitivity, thereby optimizing microbiological testing and improving clinical management.
This prospective study from India evaluates the diagnostic accuracy of RIPASA versus Modified Alvarado Score in acute appendicitis, highlighting RIPASA’s superior sensitivity and discrimination in an Asian surgical cohort.
A race-free adaptation of the MESA risk score estimates 10-year coronary heart disease risk with comparable accuracy to the original, challenging the necessity of including race/ethnicity in cardiovascular risk prediction.
A large retrospective study from Pakistan shows that LACE and HOSPITAL scores have fair accuracy in predicting 30-day readmissions among internal medicine patients, supporting their use in LMIC hospitals to target interventions and improve
Biallelic loss-of-function mutations in BPNT1 are identified as a new genetic cause of vitamin B12-dependent megaloblastic anemia, linked to disrupted ribosome biogenesis and impaired ileal vitamin B12 absorption in mouse models.
That night, my best friend cried on the phone for a long time. She said they had been married for five years, and their sex life went from five or six
Every man wants to know the answer to the same question: What kind of sex life do women actually want? This seemingly simple question has left countle
This article examines interleukin-6 (IL-6) as a key mediator of therapeutic efficacy in acute lung injury and COVID-19, highlighting its role in modulating inflammation and survival outcomes across multiple clinical interventions.
This nationwide UK study identifies key factors contributing to delayed diagnosis in childhood non-infectious uveitis, underscoring the need for improved primary care awareness and streamlined referral pathways to prevent vision-threatening
New region- and sex-specific axial length centile charts provide vital reference values for myopia monitoring and management in children, highlighting regional differences and supporting targeted interventions against rising myopia rates.
Systemic IL-6 inhibitors are linked to significantly reduced risks of diabetic retinopathy development, progression, and vision-threatening complications, suggesting therapeutic potential for diabetic eye disease.
This retrospective study identifies key patient factors that guide treatment decisions in bilateral vocal fold atrophy, highlighting the roles of symptom severity, professional voice use, and comorbidities in selecting observation, voice th
This study reveals significant sex-based disparities in access to robot-assisted surgery operative experience, showing female surgeons perform fewer robot-assisted procedures than males, potentially impacting career progression.
This study elucidates the prognostic importance of bile duct resection margin status in distal cholangiocarcinoma, revealing that margin involvement significantly affects recurrence risk in node-negative patients and identifies potential ca
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