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Maternal and Neonatal Outcomes Associated with Polyendocrine Metabolic Ovarian Syndrome During Pregnancy: Insights from a Nested Prospective Cohort Study
Diabetes & EndocrinologyGestational diabetes mellitus新生児アウトカム

Maternal and Neonatal Outcomes Associated with Polyendocrine Metabolic Ovarian Syndrome During Pregnancy: Insights from a Nested Prospective Cohort Study

By MedXY|Sep 21, 2026

This study reveals that polyendocrine metabolic ovarian syndrome (PMOS) during pregnancy increases risks of early gestational diabetes and adverse neonatal outcomes, underscoring the need for timely identification and management to improve

From Alert to Action: Enhancing Diabetes Self-Management Referrals Through Electronic Health Record Alerts
Diabetes & EndocrinologydiabetesBest Practice Advisory

From Alert to Action: Enhancing Diabetes Self-Management Referrals Through Electronic Health Record Alerts

By MedXY|Sep 21, 2026

A cluster-randomized trial demonstrates that integrating best practice advisories (BPAs) and standing orders into electronic health records significantly improves referral rates to diabetes self-management education and support (DSMES) over

Efficacy and Safety of Semaglutide According to Frailty Status: Insights from the SELECT Randomized Clinical Trial Post Hoc Analysis
Clinical UpdatessemaglutideGLP-1 receptor agonists

Efficacy and Safety of Semaglutide According to Frailty Status: Insights from the SELECT Randomized Clinical Trial Post Hoc Analysis

By MedXY|Sep 21, 2026

Semaglutide demonstrates consistent cardiovascular benefits and safety across frailty levels in overweight adults with cardiovascular disease, enhancing quality of life and frailty status without increased adverse events.

Whole-grain Consumption and Cardiometabolic Risk: A Meta-analysis of Randomized Trials
Cardiologycholesterolwhole grains

Whole-grain Consumption and Cardiometabolic Risk: A Meta-analysis of Randomized Trials

By MedXY|Sep 21, 2026

This meta-analysis of 87 randomized trials finds that increasing whole-grain intake is associated with improved cardiometabolic risk factors including reduced body weight, cholesterol, and blood pressure, particularly at daily intakes of 60

Harmonizing Estradiol Reference Ranges in Postmenopausal Women: A Breakthrough for Accurate Hormone Assessment and Risk Prediction
Diabetes & EndocrinologyBMIreference ranges

Harmonizing Estradiol Reference Ranges in Postmenopausal Women: A Breakthrough for Accurate Hormone Assessment and Risk Prediction

By MedXY|Sep 21, 2026

This article reviews the establishment of international standardized reference ranges for plasma estradiol in postmenopausal women, highlighting the influence of BMI and assay harmonization using CDC standards, with implications for therapy

GLP-1 Receptor Agonists and the Prevention of Obstructive Sleep Apnea in Type 2 Diabetes: Insights from a Large UK Cohort Study
Diabetes & Endocrinologycohort studyDPP‑4 inhibitors

GLP-1 Receptor Agonists and the Prevention of Obstructive Sleep Apnea in Type 2 Diabetes: Insights from a Large UK Cohort Study

By MedXY|Sep 19, 2026

A comprehensive UK cohort study shows that GLP-1 receptor agonists do not reduce the incidence of obstructive sleep apnea compared to DPP-4 inhibitors in obese patients with type 2 diabetes.

New 2026 EASD Guideline: Practical, Evidence-Based Care for Diabetes Distress in Adults with Type 1 and Type 2 Diabetes
Diabetes & Endocrinologypsychosocial care糖尿病ディストレス

New 2026 EASD Guideline: Practical, Evidence-Based Care for Diabetes Distress in Adults with Type 1 and Type 2 Diabetes

By MedXY|Sep 19, 2026

The 2026 EASD guideline provides practical, evidence-based recommendations for routine assessment and management of diabetes distress in adults with type 1 or type 2 diabetes, including validated screening, eight Good Practice Statements, a

Machine Learning-enhanced Steroid Profiling for Rapid Diagnosis of Congenital Adrenal Steroidogenesis Disorders
Diabetes & EndocrinologySteroid ProfilingCongenital Adrenal Disorders

Machine Learning-enhanced Steroid Profiling for Rapid Diagnosis of Congenital Adrenal Steroidogenesis Disorders

By MedXY|Sep 19, 2026

This article reviews a validated machine learning decision-tree model using LC-MS/MS steroid profiles to accurately and rapidly diagnose congenital disorders of adrenal steroidogenesis (CDAS), enhancing clinical decision-making and patient

New Consensus on Testosterone Reference Ranges for Females and Children: Outcomes of the 2024 PCOS Challenge–CDC Stakeholder Meeting
Diabetes & EndocrinologyPCOStestosterone

New Consensus on Testosterone Reference Ranges for Females and Children: Outcomes of the 2024 PCOS Challenge–CDC Stakeholder Meeting

By MedXY|Sep 19, 2026

A stakeholder consensus sets a roadmap to develop standardized, age- and sex-specific testosterone reference intervals for women, adolescent girls, and children to improve diagnosis and care for androgen-related disorders.

SGLT2 Inhibitors Enhance Recovery After Endovascular Thrombectomy in Diabetic Stroke Patients: A Multicenter Retrospective Study
Diabetes & Endocrinologydiabetic strokeSGLT2 inhibitors

SGLT2 Inhibitors Enhance Recovery After Endovascular Thrombectomy in Diabetic Stroke Patients: A Multicenter Retrospective Study

By MedXY|Sep 18, 2026

SGLT2 inhibitors administered after endovascular thrombectomy in diabetic stroke patients significantly improve 3-month functional outcomes, suggesting a promising adjunctive therapy for poststroke diabetes management.

Fenofibrate Use and Reduced Risk of Sight-Threatening Diabetic Retinopathy in Type 2 Diabetes: Insights from UK Real-World Data
Diabetes & Endocrinologyretinopathy đái tháo đườngtype 2 diabetes

Fenofibrate Use and Reduced Risk of Sight-Threatening Diabetic Retinopathy in Type 2 Diabetes: Insights from UK Real-World Data

By MedXY|Sep 18, 2026

Fenofibrate use in type 2 diabetes patients is associated with a significant reduction in the risk of sight-threatening diabetic retinopathy compared to statins, based on UK primary care data over 12 years.

Reevaluating Radioactive Iodine Therapy in T3b Differentiated Thyroid Cancer: Insights from a SEER-Based Cohort Study
Diabetes & Endocrinology放射性碘治疗differentiated thyroid cancer

Reevaluating Radioactive Iodine Therapy in T3b Differentiated Thyroid Cancer: Insights from a SEER-Based Cohort Study

By MedXY|Sep 17, 2026

This cohort study of 6,638 T3b differentiated thyroid cancer patients found no survival benefit from adjuvant radioactive iodine therapy, suggesting the need for individualized treatment strategies and prospective studies focusing on recurr

Mortality and Morbidity After Below-Knee Amputation in Diabetes: Insights from a 25-Year English Cohort Study
Diabetes & Endocrinologydiabetesbelow-knee amputation

Mortality and Morbidity After Below-Knee Amputation in Diabetes: Insights from a 25-Year English Cohort Study

By MedXY|Sep 17, 2026

This large-scale England study reveals persistently high mortality after below-knee amputation in diabetes, with one-year mortality exceeding 23%, emphasizing the need for targeted interventions focused on older, female, and comorbid patien

Comparing Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Serum Urate Control in Men with Hyperuricemia
Diabetes & EndocrinologyDietary patternsgout flare

Comparing Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Serum Urate Control in Men with Hyperuricemia

By MedXY|Sep 16, 2026

A 12-week randomized trial compared the effects of calorie-restricted DASH, carbohydrate-restricted, and low-purine diets on weight loss and serum urate levels in men with overweight or obesity and hyperuricemia, highlighting adherence and

Differential Physical Activity Responses to Diabetes Risk Reduction Interventions According to Prediabetes Phenotype: Insights from Pooled Randomized Controlled Trials
Clinical Updatesdiabetes preventionlifestyle intervention

Differential Physical Activity Responses to Diabetes Risk Reduction Interventions According to Prediabetes Phenotype: Insights from Pooled Randomized Controlled Trials

By MedXY|Sep 17, 2026

The effectiveness of lifestyle interventions promoting physical activity for diabetes risk reduction varies by prediabetes phenotype, with individuals having impaired fasting glucose showing the least response. Tailored approaches may enhan

Social Inequalities in Gestational Diabetes: Insights from a Nationwide Swedish Cohort Study
Diabetes & Endocrinologyhealth disparitiespregnancy complications

Social Inequalities in Gestational Diabetes: Insights from a Nationwide Swedish Cohort Study

By MedXY|Sep 17, 2026

This Swedish cohort study reveals growing gestational diabetes prevalence with marked disparities by social determinants such as education, income, and nativity, underscoring the need for targeted prevention and equitable care.

Oxytocin’s Role in Modulating Thyroid Function and Mental Health in Obesity: Insights from an 8-Week Clinical Trial
Diabetes & Endocrinologyobesitythyroid function

Oxytocin’s Role in Modulating Thyroid Function and Mental Health in Obesity: Insights from an 8-Week Clinical Trial

By MedXY|Sep 17, 2026

An 8-week trial reveals that intranasal oxytocin increases the free T3/free T4 ratio and correlates with improved mental health-related quality of life in adults with obesity, suggesting thyroid axis modulation as a potential mechanism for

Preserved Thalamic Bioenergetics and Neuronal Function in Painful Diabetic Peripheral Neuropathy: Insights from Dual Magnetic Resonance Spectroscopy
Diabetes & Endocrinologyneuropathic painDiabetic peripheral neuropathy

Preserved Thalamic Bioenergetics and Neuronal Function in Painful Diabetic Peripheral Neuropathy: Insights from Dual Magnetic Resonance Spectroscopy

By MedXY|Sep 15, 2026

A study using dual magnetic resonance spectroscopy reveals contrasting thalamic neuronal and bioenergetic profiles in painful versus painless diabetic peripheral neuropathy, highlighting potential biomarkers and mechanisms underlying neurop

Impact of Hypercortisolism Severity on Outcomes in Adrenocortical Carcinoma with Cushing’s Syndrome
Diabetes & EndocrinologyCushing's Syndromesurvival outcomes

Impact of Hypercortisolism Severity on Outcomes in Adrenocortical Carcinoma with Cushing’s Syndrome

By MedXY|Sep 15, 2026

This study reveals that the severity of hypercortisolism in adrenocortical carcinoma patients with Cushing’s syndrome correlates with higher metastatic risk and worse survival outcomes, highlighting its role as a marker of tumor aggressiven

Balancing Accuracy and Practicality: Should RAAS-Modifying Drugs Be Withdrawn in Primary Aldosteronism Diagnosis?
Diabetes & Endocrinologyaldosterone-renin ratiohypertension diagnosis

Balancing Accuracy and Practicality: Should RAAS-Modifying Drugs Be Withdrawn in Primary Aldosteronism Diagnosis?

By MedXY|Sep 15, 2026

This article examines the debate on whether RAAS-modifying antihypertensives should be stopped before testing for primary aldosteronism, weighing diagnostic accuracy against patient safety and feasibility.

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