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Sex-Specific Associations Between Adiposity and Dry Eye Disease: Insights from a Large UK Biobank Study
Diabetes & Endocrinologydry eye diseaseSex Differences

Sex-Specific Associations Between Adiposity and Dry Eye Disease: Insights from a Large UK Biobank Study

By MedXY|Sep 9, 2026

Central obesity in women and high overall body fat in men are linked to increased odds of dry eye disease, with distinct metabolic pathways implicated, based on a retrospective analysis of over 480,000 UK Biobank participants.

Gardnerella Enrichment in the Vaginal Microbiome of Women with Gestational Diabetes Mellitus Is Associated with Lower Fetal Birthweight Percentiles
Diabetes & EndocrinologyGestational diabetes mellitusTăng trưởng thai nhi

Gardnerella Enrichment in the Vaginal Microbiome of Women with Gestational Diabetes Mellitus Is Associated with Lower Fetal Birthweight Percentiles

By MedXY|Sep 8, 2026

This study reveals that gestational diabetes alters vaginal microbiota, increasing Gardnerella abundance, which correlates with maternal glucose levels and lower fetal birthweight percentiles.

Improved Glycaemic Control and Vascular Outcomes After MiniMed 780G Usage in Older Adults with Type 1 Diabetes: A Randomised Controlled Trial
Diabetes & Endocrinologyolder adultstype 1 diabetes

Improved Glycaemic Control and Vascular Outcomes After MiniMed 780G Usage in Older Adults with Type 1 Diabetes: A Randomised Controlled Trial

By MedXY|Sep 8, 2026

This study demonstrates that using the MiniMed 780G hybrid closed-loop system significantly improves glycaemic management and shows a trend toward better microvascular function in adults aged 65 and above with type 1 diabetes, without incre

Cushing’s Syndrome in the Elderly: Diagnostic and Therapeutic Nuances in an Aging Population
Diabetes & EndocrinologyCushing's SyndromeHypercortisolism

Cushing’s Syndrome in the Elderly: Diagnostic and Therapeutic Nuances in an Aging Population

By MedXY|Sep 8, 2026

Cushing’s syndrome in older adults requires a tailored diagnostic approach and individualized management that prioritizes functional status and quality of life over chronological age, accounting for atypical presentations and comorbidities.

Harnessing Multidomain Baseline Metrics to Predict Attrition in Diabetic Foot Ulcer Offloading Trials
Diabetes & Endocrinologyoffloading devicesattrition prediction

Harnessing Multidomain Baseline Metrics to Predict Attrition in Diabetic Foot Ulcer Offloading Trials

By MedXY|Sep 8, 2026

Baseline clinical, functional, and psychosocial metrics predict participant attrition in diabetic foot ulcer offloading device trials; integration via risk visualization enhances retention strategies and highlights technology benefits.

Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes
Diabetes & Endocrinologytype 1 diabetesEndogenous Insulin

Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes

By MedXY|Sep 8, 2026

Detectable C-peptide levels indicating residual insulin production strongly correlate with lower diabetic ketoacidosis risk in type 1 diabetes, highlighting the importance of preserving beta-cell function for improved clinical outcomes.

Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact
Diabetes & Endocrinologytype 1 diabetesanxiety

Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact

By MedXY|Sep 6, 2026

This multicentre Turkish study identifies ZnT8 autoantibodies as predominant in young siblings at risk for type 1 diabetes and highlights gestational age as a protective factor, while revealing significant anxiety changes in children and pa

Linking Female Infertility History to Type 2 Diabetes Risk: Insights from the Nurses’ Health Study II
Diabetes & EndocrinologyHbA1ctype 2 diabetes

Linking Female Infertility History to Type 2 Diabetes Risk: Insights from the Nurses’ Health Study II

By MedXY|Sep 6, 2026

This study explores the increased risk of type 2 diabetes among women with a history of infertility, highlighting specific infertility causes and implications independent of BMI.

Sarcopenic Obesity and Type 2 Diabetes Risk: Insights from the UK Biobank Study
Diabetes & Endocrinologytype 2 diabetessarcopenic obesity

Sarcopenic Obesity and Type 2 Diabetes Risk: Insights from the UK Biobank Study

By MedXY|Sep 6, 2026

This study reveals sarcopenic obesity significantly increases the risk of incident type 2 diabetes, exceeding risks from obesity or sarcopenia alone, highlighting the importance of combined muscle and adiposity assessment in diabetes preven

Menstrual Cycle Influence on Insulin Sensitivity in Type 1 Diabetes: Insights from Automated Insulin Delivery Users
Diabetes & Endocrinologyautomated insulin deliveryinsulin sensitivity

Menstrual Cycle Influence on Insulin Sensitivity in Type 1 Diabetes: Insights from Automated Insulin Delivery Users

By MedXY|Sep 4, 2026

This study elucidates how insulin sensitivity and glucose control in menstruating individuals with type 1 diabetes fluctuate across menstrual cycle phases, emphasizing gaps in current automated insulin delivery systems and guidelines.

Predicting Hypothyroidism After Hemithyroidectomy: Development and Validation of a Clinical Nomogram for Personalized Risk Assessment
Diabetes & EndocrinologyHypothyroidismHemithyroidectomy

Predicting Hypothyroidism After Hemithyroidectomy: Development and Validation of a Clinical Nomogram for Personalized Risk Assessment

By MedXY|Sep 5, 2026

A validated nomogram predicts hypothyroidism risk within 12 months after hemithyroidectomy using clinical and pathological variables, aiding tailored patient counseling and postoperative monitoring.

Levothyroxine-Induced Mild TSH Suppression Elevates Reverse T3 without Altering fT3 in Euthyroid Papillary Thyroid Microcarcinoma Patients on Active Surveillance
Diabetes & Endocrinologythyroid hormone metabolismLevothyroxine

Levothyroxine-Induced Mild TSH Suppression Elevates Reverse T3 without Altering fT3 in Euthyroid Papillary Thyroid Microcarcinoma Patients on Active Surveillance

By MedXY|Sep 6, 2026

Levothyroxine therapy lowering TSH in euthyroid PTMC patients during active surveillance raises reverse T3 levels while maintaining stable free T3, suggesting altered thyroid hormone metabolism and a compensatory adaptive response.

Unraveling Genetic Pathways in Type 1 Diabetes: Distinct HLA-DR3 and DR4 Effects on Disease Progression
Allergy & Immunologytype 1 diabetesautoimmunity

Unraveling Genetic Pathways in Type 1 Diabetes: Distinct HLA-DR3 and DR4 Effects on Disease Progression

By MedXY|Sep 5, 2026

This study reveals that genetic risk factors and immune pathways differ significantly between type 1 diabetes patients stratified by HLA-DR3 and HLA-DR4 status, providing insights into disease heterogeneity and personalized risk mechanisms.

Decoding Pancreatic Islet Single-Cell Transcriptomic Diversity Across Type 2 Diabetes Subtypes
Diabetes & Endocrinologysingle-cell RNA sequencingtype 2 diabetes

Decoding Pancreatic Islet Single-Cell Transcriptomic Diversity Across Type 2 Diabetes Subtypes

By MedXY|Sep 5, 2026

Single-cell RNA sequencing of pancreatic islets reveals distinct molecular signatures linked to specific clinical subtypes of type 2 diabetes, highlighting the heterogeneous pathophysiology and providing potential subtype-specific therapeut

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Glucose Metabolism in Youths with Cystic Fibrosis: Insights from Continuous Glucose Monitoring
Diabetes & Endocrinologycystic fibrosiscontinuous glucose monitoring

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Glucose Metabolism in Youths with Cystic Fibrosis: Insights from Continuous Glucose Monitoring

By MedXY|Sep 5, 2026

This study demonstrates that initiation of elexacaftor/tezacaftor/ivacaftor (ETI) therapy in children and adolescents with cystic fibrosis improves continuous glucose monitoring (CGM) metrics, correlating with better clinical outcomes.

Approach to the Patient: Theranostics as Precision Medicine for Neuroendocrine Tumors
Diabetes & Endocrinologyneuroendocrine tumorstheranostics

Approach to the Patient: Theranostics as Precision Medicine for Neuroendocrine Tumors

By MedXY|Sep 5, 2026

Presentation of three neuroendocrine tumor cases illustrating theranostics integration in diagnosis, treatment, and management, highlighting receptor-based imaging and personalized radionuclide therapy.

Charcot Neuro-Osteoarthropathy in Diabetes: High Risk of Hospitalization, Amputation, and Mortality Revealed by Regional Cohort Study
Diabetes & Endocrinologysurvivaldiabetes

Charcot Neuro-Osteoarthropathy in Diabetes: High Risk of Hospitalization, Amputation, and Mortality Revealed by Regional Cohort Study

By MedXY|Sep 5, 2026

Charcot neuro-osteoarthropathy (CNO) in people with diabetes is linked to frequent emergency hospitalizations, substantial risk of limb amputation, and reduced survival, highlighting urgent need for intensified multidisciplinary care.

Gestational Diabetes Mellitus: Insights from 25 Years of Research on Early Risk, Prevention, and Long-Term Outcomes
Diabetes & EndocrinologypreventionEarly Risk Factors

Gestational Diabetes Mellitus: Insights from 25 Years of Research on Early Risk, Prevention, and Long-Term Outcomes

By MedXY|Sep 5, 2026

A 25-year synthesis of research on gestational diabetes mellitus revealing early metabolic alterations, prevention strategies, optimized treatments, and lifelong consequences for mothers and offspring.

Ketoacidosis Risk with SGLT2 Inhibitors in Type 2 Diabetes: Insights from a Scandinavian Cohort Study
Diabetes & Endocrinologytype 2 diabetesketoacidosis

Ketoacidosis Risk with SGLT2 Inhibitors in Type 2 Diabetes: Insights from a Scandinavian Cohort Study

By MedXY|Sep 5, 2026

A large Scandinavian study reveals that ketoacidosis risk during SGLT2 inhibitor therapy in type 2 diabetes varies by patient factors and persists beyond early treatment, highlighting the need for ongoing risk assessment and management stra

Unraveling the Role of 11-Oxygenated Androgens in PCOS: Phenotype-Specific Profiles and Treatment Responses
Diabetes & EndocrinologyPCOSmetformin

Unraveling the Role of 11-Oxygenated Androgens in PCOS: Phenotype-Specific Profiles and Treatment Responses

By MedXY|Sep 3, 2026

This article explores how 11-oxygenated androgens differ by PCOS phenotypes and respond to first-line therapies, emphasizing their role in phenotyping and guiding treatment in polycystic ovary syndrome.

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