Cardiology
Latest news
1101 articles · 20 / page
Optimizing Post-Operative Outcomes: The Critical Impact of Specialist Cardiology Evaluation in Peri-operative Myocardial Infarction and Injury
This review analyzes evidence demonstrating that cardiologist evaluation for peri-operative myocardial infarction/injury (PMI) significantly reduces 1-year major adverse cardiac events and all-cause mortality through optimized diagnostic an
IVUS Guidance Slashes 1-Year Target Vessel Failure in Complex Bifurcation PCI: Insights from DKCRUSH VIII
The DKCRUSH VIII trial demonstrates that IVUS-guided PCI for complex coronary bifurcation lesions significantly reduces 1-year target vessel failure compared to angiography guidance, primarily by ensuring adherence to specific optimization
Mid-Regional Pro-Adrenomedullin (MR-proADM): A Superior Prognostic Sentinel in Transthyretin Cardiac Amyloidosis
This review synthesizes recent evidence identifying MR-proADM as a premier prognostic biomarker in ATTR-CM, demonstrating its ability to outperform traditional natriuretic peptides and enhance existing clinical staging systems.
Beyond the Backpressure: Targeting the Integrin αV-YAP-CTGF Axis to Halt Fibrosis in Congestive Hepatopathy
This study identifies the integrin αV-YAP-CTGF axis in liver sinusoidal endothelial cells as a primary driver of fibrosis and carcinogenesis in congestive hepatopathy. By targeting this mechanosensitive pathway, researchers demonstrated a s
Advancing Venous Thromboembolism Prediction: Insights from Large-Scale Plasma Proteomics and Mendelian Randomization
This review synthesizes findings from a landmark proteomic study identifying 23 plasma proteins associated with VTE risk, highlighting novel pathways in immunity and vascular senescence while exploring causal links through Mendelian Randomi
Beyond the Clot: Novel Proteomic Markers Reveal New Pathophysiological Pathways for Venous Thromboembolism
A large-scale proteomic meta-analysis across five cohorts identified 15 novel plasma protein markers for venous thromboembolism, highlighting the roles of the extracellular matrix, immunity, and vascular senescence in disease risk and offer
Synergistic Risk Assessment: Coronary Artery Calcium Scoring Remains Vital in Patients with Elevated Lipoprotein(a)
A large-scale multicohort study demonstrates that while elevated Lipoprotein(a) increases cardiovascular risk, Coronary Artery Calcium (CAC) scoring remains a powerful independent predictor of events, even in patients with high Lp(a) levels
Deciphering the Clinician’s Dilemma: Determinants of Antihypertensive Treatment Intensification in Older Adults
This review analyzes the complex factors influencing blood pressure management in older adults, highlighting how age, frailty, and digital health data shape clinician decisions and clinical inertia.
Targeting the Integrin αV-YAP-CTGF Axis: A New Frontier in Treating Congestive Hepatopathy and Liver Carcinogenesis
Researchers have identified a mechanosensitive signaling pathway in liver sinusoidal endothelial cells that drives fibrosis and cancer in response to chronic congestion, offering a new therapeutic target for heart-failure-related liver dise
From Pressure to Cancer: Unveiling the Integrin αV-YAP-CTGF Axis as a Therapeutic Target in Congestive Hepatopathy
Researchers have identified a novel signaling pathway in liver sinusoidal endothelial cells (LSECs) that drives fibrosis and liver cancer in congestive hepatopathy. The study highlights the Integrin αV-YAP-CTGF axis as a critical mechanism
Beyond the Clot: Novel Proteomic Markers Redefine Venous Thromboembolism Risk
This large-scale proteomic analysis identifies 15 novel protein markers for venous thromboembolism, offering new insights into the roles of immunity and extracellular matrix regulation in VTE pathogenesis beyond traditional coagulation path
The Cardiovascular-Kidney-Metabolic (CKM) Syndrome Revolution: Mapping Medication Eligibility and Multi-Systemic Benefits
This review synthesizes recent evidence on the massive scale of CKM medication eligibility in the US, the synergistic effects of pharmacotherapy with lifestyle, and emerging neuropsychiatric benefits of GLP-1 receptor agonists.
TEER vs. Medical Therapy: Redefining the Management of Atrial Functional Mitral Regurgitation
A large-scale registry analysis demonstrates that Transcatheter Edge-to-Edge Repair (TEER) significantly reduces mortality and heart failure hospitalizations in patients with atrial functional mitral regurgitation (AFMR) compared to medical
Decoding the Diabetic Heart: Five Unique Proteomic Markers Unveil Heart Failure Risk in Patients with Diabetes
Researchers from the ARIC study have identified five specific proteomic markers that uniquely predict heart failure risk in individuals with diabetes. These findings, including four novel proteins, suggest distinct pathophysiological pathwa
Sex-Specific Risk Thresholds in Aortic Regurgitation: Challenging the One-Size-Fits-All Approach to LV Remodeling
A multicenter study reveals that women with moderate-severe aortic regurgitation face higher mortality risk at lower ventricular volumes than men. Findings suggest current guidelines may require revision to include sex-specific volumetric t
Navigating the AfMR Maze: Expert Consensus and the Future of Mitral Regurgitation Diagnosis
This article examines the debate between JACC and ESC definitions for Atrial Functional Mitral Regurgitation (AfMR), highlighting why the JACC Expert Consensus offers a more robust framework for clinical prognosis and patient classification
Breaking the Brake: How Annexin A2 Inhibition Restores Mitophagy and Salvages the Infarcted Heart
This study identifies Annexin A2 as a critical negative regulator of PHB2-mediated mitophagy in myocardial infarction. By promoting PHB2 degradation via the TRIM29 ligase, ANXA2 exacerbates cardiac injury. Inhibiting ANXA2 restores mitochon
Redefining Gout Management: Cardiovascular Risk Reduction via Treat-to-Target Urate-Lowering Therapy
Achieving serum urate targets
Decoding the Diabetic Heart: Novel Proteomic Signatures of Heart Failure Risk in the ARIC Study
A comprehensive review of the ARIC study’s identification of five unique proteomic markers—four novel—that specifically predict heart failure risk in patients with diabetes, offering new insights into lipid metabolism and inflammatory pathw
Sex-Specific Risk Stratification in Aortic Regurgitation: Moving Beyond One-Size-Fits-All Thresholds
New evidence suggests that current guidelines for aortic regurgitation may overlook sex-specific risks. A recent study proposes lower surgical thresholds for both sexes and distinct volumetric cutoffs (40 mL/m² for women, 45 mL/m² for men)
Browse by specialty
Open language-specific specialty feeds and department pages.