General Surgery
Latest news
208 articles · 20 / page
Expanding Donor Pools: Outcomes of Liver Transplantation Using Grafts from Medical Assistance in Dying Donors in Canada
This Canadian multicenter study evaluates liver transplant outcomes using grafts from donation after medical assistance in dying donors, showing comparable survival and complication rates to standard donors and increasing transplant activit
Breaking New Ground: The First Genetically Engineered Pig-to-Human Liver Xenotransplantation
This landmark study reports the first successful genetically engineered pig auxiliary liver transplanted into a living human, revealing critical insights on immunological compatibility and post-transplant complications, advancing liver xeno
Postoperative Vasopressor Use After Noncardiac Surgery: Patterns, Outcomes, and Clinical Implications from a Global Observational Study
An international study reveals that postoperative vasopressor infusions after noncardiac surgery vary widely across hospitals and are linked to higher mortality and complications, highlighting the need for optimized management strategies.
Simultaneous Liver Transplant and Sleeve Gastrectomy: A Dual Approach to Combat Obesity and MASLD with Durable Outcomes
Combining liver transplant with sleeve gastrectomy yields sustained weight loss, improved metabolic syndrome, and reduced liver allograft steatosis, without increasing mortality or graft loss, offering an effective treatment for obese patie
Bariatric Surgery Significantly Reduces Risk of Developing Major Obesity-Related Comorbidities: Insights from a Large Veterans Cohort
A large retrospective cohort study reveals bariatric surgery markedly lowers the incidence of key metabolic comorbidities compared to weight management alone in obese veterans, supporting its role in durable obesity-related risk reduction.
Harnessing Digital Health: Efficacy of Virtual Reality and Interactive Tools in Reducing Pediatric Perioperative Anxiety and Pain
This network meta-analysis of 49 RCTs demonstrates that digital health interventions, notably virtual reality, 2D videos, and 2D games, significantly reduce perioperative anxiety and pain and improve induction compliance in pediatric surgic
Refining Sentinel Lymph Node Biopsy Decisions in Melanoma: Insights from the MERLIN_001 Gene Expression Profiling Study
The MERLIN_001 study validates a combined clinicopathological and gene expression profile test that accurately predicts sentinel lymph node metastasis risk in patients with cutaneous melanoma, potentially guiding safer, more personalized su
Advancing Sustainability in Gynecologic Surgery: 12 Practical Steps to Reduce Environmental Impact
This article reviews 12 evidence-backed strategies to enhance sustainability in gynecologic surgery by minimizing single-use disposables and reducing carbon emissions in the operating room.
Xenotransplantation: Bridging the Gap in Liver Transplantation with Genetically Modified Pig Organs
Recent advances in genetically modified pig-to-human organ transplantation offer promising solutions for acute liver failure, bridging critical gaps in organ availability and raising important ethical and regulatory considerations.
Evaluating Fentanyl Use in Pediatric Ileocolic Intussusception Reduction: Implications for Pain Management and Success Rates
A large multicenter study finds no association between fentanyl administration and failed reduction of pediatric ileocolic intussusception, supporting its safe use for analgesia during the painful reduction procedure.
Enhancing Surgical Patient Safety: Impact of the SIPS Handover System on Clinical Outcomes
The SIPS surgical handover system significantly improves handover quality, patient vital signs, and staff safety perceptions without prolonging meeting times, enhancing safety in emergency general surgery.
Impact of Early Extracranial Surgery on One-Year Outcomes After Traumatic Brain Injury: Insights from the TRACK-TBI Study
Early extracranial surgery following moderate-severe traumatic brain injury or positive CT findings is linked to worse cognitive, functional, and quality of life outcomes at one year, highlighting the need to refine surgical timing and post
Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?
This retrospective national cohort study reveals that Medicare Advantage (MA) enrollees undergoing major cancer surgery are less likely to receive care at high-quality hospitals compared to traditional Medicare beneficiaries, raising concer
Thoracoscopic versus Open Oesophagectomy for Thoracic Oesophageal Cancer: Insights from the JCOG1409 MONET Trial
The JCOG1409 MONET phase 3 trial establishes that thoracoscopic oesophagectomy is non-inferior to open oesophagectomy in overall survival for resectable thoracic oesophageal cancer, with comparable safety profiles and postoperative outcomes
Long-Term Comparative Outcomes of Gastric Bypass and Sleeve Gastrectomy in Type 2 Diabetes: Evidence from a Swedish Matched Cohort Study
A Swedish nationwide study reveals Roux-en-Y gastric bypass yields superior long-term benefits in type 2 diabetes remission and reduced mortality compared to sleeve gastrectomy, despite higher risks of nutritional deficiencies and psychiatr
Evaluating the Impact of a Perioperative Care Bundle on Surgical Site Infection Prevention After Abdominal Surgery: Insights from the EPO2CH Trial
This comprehensive review explores the EPO2CH trial, which assessed a multi-component care bundle’s effectiveness in reducing surgical site infections after abdominal surgery, highlighting key findings, limitations, and clinical implication
Neoadjuvant FOLFIRINOX versus Gemcitabine-Based Chemoradiotherapy in Resectable and Borderline Resectable Pancreatic Cancer: Insights from the PREOPANC-2 Phase 3 Trial
The PREOPANC-2 trial compared neoadjuvant FOLFIRINOX and gemcitabine-based chemoradiotherapy in resectable and borderline resectable pancreatic cancer, finding no significant overall survival difference between the two regimens.
Optimizing Mesh Weight to Reduce Recurrence Reoperations in Laparoscopic Inguinal Hernia Repair
A Danish cohort study identifies that using mesh weighing 45-65 g/m² in laparoscopic inguinal hernia repair results in the lowest reoperation rate for recurrence, guiding surgical mesh selection for better patient outcomes.
Proactive Versus Reactive Intraoperative Blood Pressure Management: Insights from the PRETREAT Randomized Clinical Trial
The PRETREAT trial found that proactive blood pressure management tailored by risk of intraoperative hypotension does not reduce postoperative functional disability compared to standard care in noncardiac surgery.
Duct-to-Mucosa versus Other Pancreaticojejunostomy Techniques for Preventing Postoperative Pancreatic Fistula: Updated Evidence and Clinical Insights
This Cochrane review update evaluates duct-to-mucosa pancreaticojejunostomy compared to other anastomotic techniques following pancreaticoduodenectomy for preventing postoperative pancreatic fistula, finding very low-certainty evidence and
Browse by specialty
Open language-specific specialty feeds and department pages.