General Surgery
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Renal Denervation Shows Sustained Blood Pressure Reduction and Safety Over 24 Months in SPYRAL HTN-ON MED Trial
The SPYRAL HTN-ON MED trial demonstrates that renal denervation provides significant long-term reductions in both ambulatory and office systolic blood pressure with good safety, supporting its role in managing hypertension.
Five-Year Outcomes of Per-Oral Endoscopic Myotomy vs. Laparoscopic Heller’s Myotomy Plus Dor Fundoplication in Idiopathic Achalasia
A multicenter randomized trial shows POEM is non-inferior to LHM plus Dor fundoplication for achalasia symptom control at 5 years, with differing reflux profiles.
Advancing Organ Preservation in Locally Advanced Rectal Cancer: Insights from the CAO/ARO/AIO-16 Phase 2 Trial
Total neoadjuvant therapy combined with watch-and-wait strategies achieves a 37% clinical complete response rate in locally advanced rectal cancer with manageable toxicity, offering an organ-preserving alternative to surgery.
Endoscopic Ultrasound-Guided Gastroenterostomy Reduces Reintervention in Malignant Gastric Outlet Obstruction: Insights from the Multicentre DRA-GOO Trial
A multicentre RCT demonstrated that endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) significantly lowers 6-month reintervention rates and improves gastric outlet obstruction symptoms compared to duodenal stenting in unresectabl
Intraoperative Indocyanine Green Fluorescence Angiography in Rectal Cancer Surgery: Insights from the IntAct Trial
The IntAct randomized trial investigated whether intraoperative indocyanine green (ICG) fluorescence angiography reduces clinical anastomotic leaks after rectal cancer surgery, showing a trend toward leak reduction but no statistically sign
Appendicectomy Plus Medical Therapy Significantly Reduces Relapse in Ulcerative Colitis: Insights from the ACCURE Trial
The ACCURE trial demonstrates that laparoscopic appendicectomy combined with standard medical therapy significantly lowers 1-year relapse rates compared to medical therapy alone in ulcerative colitis patients in remission.
Revolutionizing Wound Healing Assessment: The Role of LC-OCT and AI
This study explores the integration of line-field confocal optical coherence tomography (LC-OCT) with artificial intelligence (AI) to enhance wound healing evaluations, providing deeper insights into clinical interventions.
Quercetin as an Adjunct for Post-Cesarean Pain: Clinical Promise from a Randomized Controlled Trial
Preoperative Quercetin significantly reduces post-cesarean pain and accelerates patient mobilization, offering a safe adjunct to current pain management protocols.
Understanding Liver Cysts: Are They Dangerous?
Explore liver cysts, their causes, symptoms, risks, treatment, and prevention strategies to demystify this common condition.
The Benefits of Cupping Therapy for Athletes and Its Role in Sports Injury Treatment
Cupping therapy, rooted in traditional Chinese medicine, offers athletes muscle relaxation, enhanced recovery, improved circulation, pain relief, immune support, and mental relaxation, making it a valuable tool for sports performance and in
When Do Thyroid Nodules Require Surgery? Clear Answers Here
Thyroid nodules larger than 4 cm often require surgery due to potential compression of surrounding tissues, but smaller nodules with signs of malignancy or symptoms may also need surgical intervention. This article explains the criteria in
Surgery or Radiofrequency Ablation for Small Hepatocellular Carcinoma: Insights from the SURF Trials
The SURF trials found no significant difference in survival or recurrence-free outcomes between surgery and radiofrequency ablation for small hepatocellular carcinoma, supporting RFA as a less invasive, equally effective option.
Long-Term Outcomes of Transoral Surgery with Risk-Adapted Adjuvant Therapy in HPV-Positive Oropharyngeal Cancer: Results from the E3311 Trial
The E3311 phase II trial shows excellent long-term survival with deintensified postoperative management after transoral surgery in HPV-associated oropharyngeal cancer, with most patients spared from high-dose radiation and chemotherapy.
Surgery versus Radiofrequency Ablation for Small Hepatocellular Carcinoma: Insights from the SURF-RCT and SURF-Cohort Trials
The SURF trials found no significant difference in survival or recurrence between surgery and radiofrequency ablation for small hepatocellular carcinoma, supporting both as valid first-line options.
Online Video Versus Face-to-Face Preoperative Consultation for Major Abdominal Surgery: Insights from the VIDEOGO Non-Inferiority Trial
The VIDEOGO trial shows that online video consultations are non-inferior to face-to-face consultations for preoperative assessment in major abdominal surgery, achieving similar patient satisfaction and information recall.
Early Postoperative PTH as a Reliable Predictor of Hypoparathyroidism After Total Thyroidectomy
A single parathyroid hormone (PTH) measurement 6 hours after total thyroidectomy can accurately predict the risk of transient and permanent hypoparathyroidism, enabling targeted monitoring and potential reduction in hospital stays.
The Hidden Costs of Elective Surgeries for Older Adults with Serious Illnesses
Older adults with serious illnesses face increased hospital stays and costs post-surgery, highlighting the need for integrated palliative care.
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