Psychiatry
Latest news
289 articles · 20 / page
Heart Rate Variability Biofeedback in Substance Use Disorder: Emerging Evidence from a Randomized Clinical Trial and Contextual Review
Second-generation heart rate variability biofeedback (HRVB) shows promise in reducing craving, negative affect, and substance use in adults with substance use disorder (SUD), supporting its potential as an adjunctive treatment in early reco
Unraveling ADHD: Gut Microbial Signatures and the Role of SCFA Deficiency in Symptom Pathogenesis
Recent research reveals distinct gut microbial and metabolic profiles linked to ADHD symptoms, highlighting short-chain fatty acid deficiency as a key mechanism driving hyperactivity and inattention.
Restoring Cognitive Function After Adolescent Alcohol Exposure: The Promise of Synbiotic Therapy Targeting the Microbiota-Gut-Brain Axis
A synbiotic intervention reverses alcohol-induced cognitive deficits in adolescent mice by modulating gut microbiota and brain metabolism, suggesting potential therapeutic avenues for alcohol-related neurobehavioral impairments.
Soft Drink Consumption and Depression: The Gut Microbiome Connection, Especially Eggerthella
This analysis explores how soft drink consumption correlates with major depressive disorder (MDD), revealing gut microbiome alterations—particularly in Eggerthella abundance—that may mediate this association, highlighting potential interven
Cytisinicline Enhances Smoking Cessation in COPD Patients: Post Hoc Insights from the ORCA-2 and ORCA-3 Trials
Cytisinicline significantly improves smoking cessation rates and is well tolerated in smokers with self-reported COPD, supporting its use as an effective treatment option for this high-risk population.
Childhood Loneliness: A Lasting Risk Factor for Cognitive Decline and Dementia in Later Life
Childhood loneliness significantly increases the risk of cognitive decline and dementia in middle-aged and older adults, independent of adult loneliness, highlighting the importance of early psychosocial interventions.
Brain Connectome Modulates the Impact of Adverse Childhood Experiences on Mental Health in Preadolescents
This cohort study reveals that whole-brain functional connectivity alters the link between adverse childhood experiences and psychiatric disorders in children, particularly for threat-related exposures and females, suggesting a neurobiologi
Linking Alcohol Consumption Per Capita to Suicide Mortality: Insights from a Meta-Analysis
A meta-analysis found a population-level association between increased per capita alcohol consumption and higher suicide mortality, without sex differences, suggesting alcohol reduction as a vital component in suicide prevention.
Unveiling the Burden and Trajectories of Perinatal Anxiety and Depression in a Major Urban Medical Center
A retrospective study identifies critical gaps in screening and treatment of perinatal anxiety and depression, revealing prevalence rates, symptom trajectories, and the impact of mental health services in 3051 women.
Ammoxetine Shows Promise as Effective and Well-Tolerated Treatment for Major Depressive Disorder: Insights from a Phase 2 Randomized Trial
A phase 2 trial in adults with major depressive disorder demonstrated that ammoxetine at 40 mg/d and 60 mg/d significantly improved depressive symptoms compared to placebo and was generally well tolerated, offering a novel treatment option
Evaluating the Patient Health Questionnaire-15 and Somatic Symptom Scale-8: Insights from a Systematic Review and Meta-Analysis
This article critically reviews measurement properties of the PHQ-15 and SSS-8, two key instruments assessing somatic symptom burden, highlighting reliability, validity, and clinical applicability based on meta-analyzed evidence from over 3
Theta Burst Stimulation of the Temporo-Parietal Cortex for Persistent Auditory Hallucinations in Schizophrenia: A Comprehensive Review of a Phase 3 Randomised Multicentre Trial and Contextual Evidence
This review synthesizes evidence on bilateral continuous theta burst stimulation (cTBS) of the temporo-parietal cortex for persistent auditory verbal hallucinations (AVH) in schizophrenia, focusing on a landmark German phase 3 trial demonst
Add-on Probiotics for Inflammatory Depression: Insights from a Double-Blind Randomized Placebo-Controlled Trial
This study evaluated the antidepressant effects of a Lactobacillus probiotic in overweight depressed patients with systemic low-grade inflammation, revealing no overall benefit but highlighting fecal formic acid as a potential biomarker for
Enhancing Vagal Nerve Function with Multi-Species Probiotics: A Promising Therapeutic Avenue for Major Depression
A 3-month RCT demonstrates that multi-species probiotic supplementation improves vagal nerve function, gut microbiome composition, and sleep quality in patients with major depression, suggesting novel gut-brain axis interventions.
Harnessing AI for Personalized Depression Treatment: Insights from the AID-ME Cluster Randomized Trial
The AID-ME trial demonstrates that an AI-powered clinical decision support system significantly improves remission rates and accelerates symptom improvement in moderate to severe major depressive disorder.
Accelerating Depression Recovery: The Impact of Measurement-Based Care in Pakistan’s Low-Resource Settings
A randomized clinical trial in Pakistan demonstrates that measurement-based care accelerates antidepressant treatment response and remission in major depressive disorder compared to standard care, underscoring its potential in low-resource
Personalized High-Definition Transcranial Direct Current Stimulation: A Promising Rapid Intervention for Moderate to Severe Depression
A randomized clinical trial demonstrates that personalized high-definition transcranial direct current stimulation (HD-tDCS) significantly improves mood in patients with moderate to severe depression, showing faster and comparable effect si
Smart-T Digital Intervention Enhances Smoking Cessation Among Low-Income Adults: Insights from a Randomized Clinical Trial
The Smart-T smartphone intervention significantly improves 7-day smoking abstinence at 26 weeks in low-income adults, outperforming the standard QuitGuide app when combined with nicotine replacement therapy.
Impact of Graphic Health Warnings on Little Cigar and Cigarillo Use: Evidence from a Randomized Clinical Trial
A randomized trial demonstrates that graphic health warnings on little cigars and cigarillos significantly increase quitting intentions and related behaviors compared to FDA text-only warnings or no warnings, highlighting the need for enhan
Evaluating the Role of Behavioral Therapy in Enhancing Buprenorphine Treatment Outcomes for Opioid Use Disorder: Insights from a Secondary Analysis of Four Randomized Clinical Trials
A secondary analysis of four randomized trials reveals that additional behavioral therapy does not significantly improve opioid abstinence, retention, or functional outcomes when added to buprenorphine and medical management in opioid use d
Browse by specialty
Open language-specific specialty feeds and department pages.