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This study investigates how the timing of primary palate repair before 15 months influences early speech outcomes, finding that even slight delays increase the risk of passive cleft speech characteristics by age 36 months.
A phase 2 trial shows pembrolizumab combined with low-dose quad-shot radiotherapy yields encouraging response rates and survival outcomes in recurrent, unresectable head and neck squamous cell carcinoma.
This randomized trial demonstrates that adding virtual reality-based vestibular rehabilitation to home exercises significantly improves symptom severity and dynamic postural control in vestibular migraine patients.
A multicenter study demonstrates the safety and effectiveness of MED-EL cochlear implants in children under 12 months and in 12-71 month-olds with residual hearing, supporting expanded pediatric CI candidacy.
Endoscopic sinus surgery significantly improves quality of life in adults with recurrent acute rhinosinusitis compared to medical treatment alone, demonstrating its safety and efficacy in managing this burdensome condition.
This article reviews the global clinical variation in surgical management of idiopathic subglottic stenosis, highlighting heterogeneity in techniques, treatment algorithms, and satisfaction levels among clinicians across 42 countries.
Machine learning models can effectively predict major 30-day complications following glossectomy for tongue cancer, improving individualized risk assessment over traditional methods.
Pediatric button battery ingestions increased over 15 years, with larger batteries and more esophageal impactions. Delays in caregiver recognition drive prolonged exposure, contributing to serious complications. Public awareness is crucial
Cryotherapy in benign subglottic and tracheal stenosis shows comparable outcomes to standard endoscopic treatments, with subgroup evidence suggesting benefits of non-thermal cryotherapy. Prospective studies are warranted.
This study reveals a significant association between GLP-1 receptor agonist therapy and increased risk of smell and taste disturbances in type 2 diabetes patients, highlighting the need for awareness and monitoring.
This phase II trial demonstrates significant antitumor activity of trastuzumab rezetecan in both HER2-high and HER2-low advanced salivary gland carcinoma with a manageable safety profile, offering new hope for this challenging malignancy.
This study details the early-onset vocal symptoms and cutaneous features of lipoid proteinosis, highlighting significant, sustained voice improvements after microlaryngosurgery and supporting early surgical intervention for optimizing patie
Tensioning glottoplasty, a novel combined endolaryngeal and external surgical technique, significantly elevates fundamental voice frequency in transgender women by integrating anterior vocal fold shortening and enhanced longitudinal tension
This study introduces a novel columella flap based on lip lifting markings for nasal columella reconstruction, demonstrating significant improvements in aesthetic and functional outcomes with minimal complications in a 20-patient cohort.
The addition of perioperative pembrolizumab to standard care improves event-free survival in locally advanced head and neck squamous cell carcinoma, with cost-effectiveness dependent on PD-L1 combined positive score.
This article reviews the utility of pitch strength and percent vocal creak as automated acoustic biomarkers to assess treatment response in adductor laryngeal dystonia, highlighting their correlations with traditional measures yet limited g
A multimodal human factors program enhances team communication, nontechnical skills, and workflow during pediatric airway endoscopy, supporting OR culture change despite unchanged immediate clinical outcomes.
This study prospectively characterizes voice changes over 12 months in transmasculine adolescents and young adults receiving testosterone therapy, demonstrating significant lowering of pitch, improved voice congruence, and reduced anxiety,
This review analyzes the increased incidence of migraine and sinus headaches in primary rhinoplasty patients, emphasizing the clinical significance of screening rhinogenic headache triggers during septorhinoplasty to enhance both symptomati
This retrospective study identifies key patient factors that guide treatment decisions in bilateral vocal fold atrophy, highlighting the roles of symptom severity, professional voice use, and comorbidities in selecting observation, voice th
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