Otorhinolaryngology
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Diagnostic Performance of Anti-Epstein-Barr Virus BNLF2b in Suspected Nasopharyngeal Carcinoma
P85-Ab, an anti-EBV BNLF2b antibody test, showed excellent accuracy for suspected nasopharyngeal carcinoma and outperformed older EBV markers in most outpatient settings.
Earlier Cricopharyngeal Intervention May Improve Oral Intake in Absent UES Opening After Neurological Injury
A small retrospective series suggests that cricopharyngeus-targeted procedures can improve upper esophageal sphincter opening and oral intake after neurological injury, but aspiration risk often persists and ongoing swallowing therapy remai
Fatigue After Thyroidectomy: What Patients Actually Experience
A qualitative study found that fatigue after thyroidectomy is common, disruptive, and often unexpected. Patients described major impacts on work and daily life, and many wanted surgeons to warn them about it before surgery.
Identifying High-Risk Children Safe for Same-Day Discharge After Tonsillectomy
Children with obesity and severe OSA usually stay overnight after tonsillectomy, but this study found most had no major complications. Oxygen nadir and AHI may help identify very low-risk patients who could be considered for same-day discha
Systematic V2 Vagal Stimulation Improves Detection of Post-Thyroidectomy Vocal Cord Dysfunction and May Better Guide Staged Surgery
A 2026 cross-sectional study suggests that routine postdissection vagal stimulation during thyroidectomy detects recurrent laryngeal nerve dysfunction more sensitively than RLN stimulation alone and may reduce the risk of bilateral vocal co
A CBT-Based Mobile App Significantly Reduced Tinnitus Distress in a Sham-Controlled Randomized Trial
In a 60-patient randomized trial, a digital therapeutic app delivering tinnitus education and CBT elements produced large, durable reductions in tinnitus-related distress over 16 weeks, with no serious safety concerns.
3D-Printed Temporal Bones Provide a Reliable, Objective Way to Assess Mastoidectomy Skill Across Otolaryngology Training
A prospective single-center study found that final product analysis on 3D-printed temporal bones reliably distinguished mastoidectomy performance by residency level and may support competency-based assessment.
Sustained Locoregional Control With Deintensified Chemoradiotherapy for HPV Oropharyngeal Carcinoma
A cohort study demonstrates that reduced-dose 60-Gy chemoradiotherapy effectively maintains locoregional control in HPV-positive oropharyngeal cancer patients while minimizing treatment toxicity, with 5-year survival rates exceeding 92%.
Impact of Immunocompromise on Survival in HPV-Positive Throat Cancer Patients
This study examines how pre-existing immunocompromise affects survival and outcomes in patients with HPV-positive oropharyngeal cancer treated surgically. Immunocompromised patients showed significantly worse overall survival compared to no
Ergonomic Strain Is Common in Otolaryngology Surgery, With Pain Rising as Cases Become More Difficult and Prolonged
A prospective study found frequent medium-to-high ergonomic risk and measurable postoperative pain among otolaryngology surgeons, highlighting modifiable occupational hazards in routine head and neck surgery.
Immunotherapy Prescribing Patterns and Immune-Related Adverse Events in Head and Neck Cancer
A large claims-based study reveals pembrolizumab dominates immunotherapy prescribing for head and neck cancer, with minimal usage growth since FDA approval. Immune-related adverse events occurred in 41.2% of patients, linked to specific com
Radiation-Induced OME: Bacterial Colonization Elevates Early Recurrence Risk Yet Lacks Long-Term Prognostic Value
Radiation-induced otitis media with effusion (RI-OME) shows heightened bacterial colonization with opportunistic pathogens. Although microbial presence predicts early recurrence (≤4 weeks post-tympanocentesis), it does not independently inf
Post-Thyroidectomy Calcium Strategies: Routine vs. PTH-Guided Supplementation Show Similar Efficacy
A randomized trial comparing routine calcium supplementation with PTH-guided selective supplementation found no significant difference in preventing post-thyroidectomy hypocalcemia, offering flexibility in clinical practice.
RAI Outperforms mFI-5 in Predicting Post-UPPP Complications: A Frailty Stratification Breakthrough
The Risk Analysis Index (RAI) significantly outperforms the modified frailty index-5 (mFI-5) in predicting mortality and major complications after uvulopalatopharyngoplasty, supporting its adoption for preoperative risk assessment in sleep
Amivantamab Falls Short of Tumor Shrinkage in Recurrent or Metastatic Adenoid Cystic Carcinoma, but Disease Stabilization Was Common
In a phase 2 trial, amivantamab did not meet its primary response endpoint in recurrent/metastatic adenoid cystic carcinoma, but most patients achieved stable disease and toxicity was generally manageable.
Cartilage Ear Piercings Carry Nearly Double the Complication Risk of Lobule Piercings in a Large Adult Survey
In a large survey of adult ear piercings, auricular cartilage piercings had higher complication and removal rates than lobule piercings, reinforcing the need for careful counseling and informed consent.
Upper Airway Fat Volume Predicts Patient Discomfort During Office-Based Laryngeal Surgery, Study Finds
A retrospective analysis of 40 patients undergoing transnasal office-based laryngeal surgery reveals that increased parapharyngeal fat at the palatal level is significantly associated with reduced procedural tolerance. The findings highligh
More Fat in the Upper Airway Means Less Tolerance for Awake Laryngeal Surgery, Study Finds
Research reveals that increased parapharyngeal fat volume at the palatal level correlates with reduced patient tolerance during transnasal office-based laryngeal surgery, suggesting anatomical factors play a significant role in procedural c
Determinants of Circulating Tumor HPV DNA in Surgically Treated Oropharyngeal Cancer
This study identifies clinicopathologic factors linked to pre- and postoperative levels of circulating tumor HPV DNA (ctHPVDNA) in HPV-mediated oropharyngeal cancer patients treated with upfront surgery, offering insights for disease monito
Beyond Binary: A 4-Stage Risk Stratification Tool Transforms Cochlear Implant Candidacy Assessment
Researchers developed a novel 4-level classification system using routine audiometric data to estimate cochlear implant candidacy likelihood, moving beyond traditional binary screening approaches to support personalized shared decision-maki
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