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MedXY News/Ophthalmology

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Ophthalmology

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Ophthalmology

Clinical Impact of Contact Lens Use in Fungal Keratitis: Insights from an 8-Year Retrospective Study

This study compares contact lens-associated and non-contact lens-associated fungal keratitis, highlighting earlier presentation and better medical therapy outcomes in contact lens users versus a more complicated course in non-users.

Oct 28, 2026
news

Quantitative Vascular Severity Scoring Enhances Insights into Retinopathy of Prematurity Across Diverse Populations

This study compares retinopathy of prematurity severity in US and Indian infants using an AI-derived vascular severity score, revealing epidemiological and pathophysiological differences that could impact diagnosis and management globally.

Oct 27, 2026
news

Cost Analysis of Outpatient Ophthalmic Procedures

This study evaluates the financial feasibility and efficiency of common outpatient ophthalmic surgeries at ambulatory surgical centers (ASCs) and hospital outpatient departments (HOPDs) relative to Medicare reimbursement in 2025 and beyond.

Oct 27, 2026
news

Uncovering Novel Genetic Contributors to Usher Syndrome: Insights from Comprehensive Mouse Knockout Models

A large-scale phenotypic screen of 9,139 knockout mouse lines identified 18 candidate genes linked to retinal and hearing abnormalities, offering promising new targets for understanding and diagnosing Usher syndrome.

Oct 26, 2026
news

Optimizing Intraocular Lens Power Calculations in Extremely Long Eyes: The Role of Axial Length Adjustment and AL/R Ratio

This study highlights the superiority of the Holladay 1 formula combined with Wang-Koch axial length adjustment in predicting refractive outcomes in eyes with axial length ≥30 mm, introducing the AL-to-corneal radius ratio as a novel strati

Oct 25, 2026
news

Charlson Comorbidity Index as a Predictor of Visual Outcomes in Retinal Vein Occlusion-Related Macular Edema: Insights from a Decade-Long Cohort Study

Higher Charlson Comorbidity Index scores correlate with worse 1-year visual acuity outcomes in macular edema secondary to retinal vein occlusion, highlighting the impact of systemic health on ocular prognosis.

Oct 24, 2026
Ophthalmology

Impact of 24-Hour Blood Pressure Variability on Retinal Nerve Fiber Layer Progression in Primary Open-Angle Glaucoma

Lower systemic blood pressure, especially minimum values measured over 24 hours, is associated with accelerated retinal nerve fiber layer loss in primary open-angle glaucoma, highlighting the prognostic value of ambulatory BP monitoring.

Oct 23, 2026
Diabetes & Endocrinology

Evaluating Anti-VEGF Retreatment Outcomes in Diabetic Macular Edema Patients Returning After Lost to Follow-Up with Stabilized Vision

This nationwide study examines visual and anatomical responses to anti-VEGF retreatment in diabetic macular edema patients who returned with stabilized vision after being lost to follow-up, highlighting suboptimal gains and implications for

Oct 23, 2026
news

Optimizing Peri-Implant Tissue Dimensions: Timing and Materials in Crestal Soft-Tissue Augmentation

This study demonstrates that prior soft-tissue augmentation using autogenous grafts before flapless implant placement significantly enhances peri-implant tissue dimensions compared to simultaneous augmentation or collagen substitutes, under

Oct 21, 2026
Superintelligence

Predicting Central Serous Chorioretinopathy Outcomes Using Interpretable AI-Driven OCT Biomarkers: Insights from a Multicenter Cohort Study

A multicenter study demonstrates that interpretable machine learning applied to baseline OCT biomarkers accurately predicts chronicity in central serous chorioretinopathy, facilitating early risk stratification and personalized management.

Oct 21, 2026
news

Ocular Metastasis Over Four Decades: Clinical Patterns, Survival, and Therapeutic Outcomes in 569 Patients

A 40-year retrospective study of 569 patients with ocular metastases reveals persistently poor survival, dominated by breast and lung primaries, with vision often preserved through treatment despite no significant survival improvements over

Oct 20, 2026
news

Prognostic Value of 15-GEP/PRAME Assay With or Without Confirmatory Cytopathology in Uveal Melanoma: Insights From the Collaborative Ocular Oncology Group Study 2

This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is

Oct 20, 2026
Clinical Updates

Trends in Spending on Corrective Lenses: An Evidence-Based Review on Expenditures, Barriers, and Policy Implications

Corrective lens spending affects nearly 20% of the US population, with half paying fully out-of-pocket, highlighting substantial financial burdens and access barriers. Evidence from clinical trials and epidemiologic studies underscores cost

Oct 19, 2026
Oncology

Long-Term Outcomes of 103Pd Plaque Brachytherapy for Choroidal Melanoma: Insights into Visual Preservation and Ocular Health in the Second and Third Decades

This study reports durable tumor control and meaningful visual preservation up to 20 years after 103Pd plaque brachytherapy for choroidal melanoma, providing valuable long-term data for clinical decision-making.

Oct 18, 2026
news

When Is High-Level Disinfection Needed for Reusable Ophthalmic Devices? A Multisociety Position Paper Explained

A multisociety task force finds routine high-level disinfection (HLD) of reusable ophthalmic devices unnecessary in most clinics, recommends targeted HLD only for higher-risk encounters, and urges alignment of regulations with evidence.

Oct 17, 2026
news

Evaluating the Impact of a Digital Companion App in Periodontal Therapy: Insights from a Multi-Center Randomised Controlled Trial

A multi-center RCT assessing the adjunctive use of the Paro-ComPas app in periodontal care found no significant overall benefit, though moderate app engagement showed potential for improved plaque control.

Oct 16, 2026
Clinical Updates

Prevalence of Diabetic Retinopathy and Cardiovascular Risk Factors Among Diverse Hispanic/Latino Adults: Insights from the HCHS/SOL and SOL Ojos Studies

More than one-third of Hispanic/Latino adults with diabetes exhibit diabetic retinopathy (DR), with significant variability across backgrounds. Hypertension notably associates with DR and vision-threatening DR, highlighting the need for tar

Oct 16, 2026
Diabetes & Endocrinology

Impact of Donor Diabetes Severity on 1-Year Outcomes After Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study

A thorough secondary analysis of a randomized clinical trial reveals no significant association between cornea donor diabetes severity and graft success, endothelial cell loss, or morphometric parameters at 1 year post-DMEK, supporting the

Oct 15, 2026
news

Corneal Epithelial Changes Induced by CDK4/6 Inhibitors in HR+ Breast Cancer: Clinical Insights and Implications

CDK4/6 inhibitor therapy in hormone receptor-positive breast cancer is linked to increased corneal epithelial alterations, including punctate epitheliopathy and vortex keratopathy, independent of aromatase inhibitor effects or tear film dys

Oct 14, 2026Sign in to read
news

Evaluating Mitomycin C Delivery Methods in Trabeculectomy: Injection Versus Sponge Application

Mitomycin C applied via injection or sponge during trabeculectomy offers comparable intraocular pressure control and safety, with injection potentially yielding more favorable bleb morphology and fewer postoperative interventions.

Oct 13, 2026
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