Section
A novel noninvasive imaging technique using [18F]GP1 PET/CT enables direct identification of thrombi in acute ischemic stroke, improving etiologic classification and predicting recurrence risk, heralding mechanism-based stroke management.
This large prospective cohort study found no significant association between prenatal organophosphate pesticide exposure and autism-related traits in children, after comprehensive adjustments including maternal diet and sociodemographic fac
Cherry angiomas are significantly more prevalent and occur at younger ages in individuals with Neurofibromatosis Type 1 (NF1), linked to biallelic NF1 inactivation in vascular cells. This discovery expands the vascular phenotype of NF1 and
Liver transplantation facilitates early neurocognitive recovery in end-stage liver disease patients by restoring cortical network activities, with S-methyl-5′-thioadenosine playing a pivotal neuroprotective role through modulating neu
This case series examines eight patients experiencing dysphonia after vagus nerve stimulator placement, highlighting variable and transient vocal fold motion changes during device cycling.
This multicenter study reveals that recent mechanical venous thrombosis risk factors markedly increase the risk of cryptogenic ischemic stroke in young adults, especially in those under 40 and with patent foramen ovale, independent of throm
The elderly mobility scale calculator (EMS calculator) is a validated clinical assessment tool designed specifically to evaluate functional mobility i
This multicenter study reveals that recent mechanical venous thrombosis risk factors within 14 days significantly increase the risk of cryptogenic ischemic stroke in young adults, notably in those under 40 and with patent foramen ovale, ind
The RNF213 p.R4810K variant independently increases risk and severity of extracranial carotid artery disease, distinct from its known association with intracranial atherosclerosis, highlighting new insights into vascular disease genetics an
Advanced MRI analyses identify three biologically distinct subtypes of white matter hyperintensities (WMHs), linking specific lesion evolution patterns with neurodegeneration and vascular/metabolic risks, offering refined insights into cere
This study compares motor-unit reinnervation and functional recovery in severe Parsonage-Turner syndrome and surgically managed traumatic brachial plexopathy, highlighting spontaneous recovery in PTS and benefits of early reconstruction in
This prospective registry reveals a significantly increased risk of stroke or transient ischemic attack within 30 days after pulsed field ablation compared to radiofrequency ablation for atrial fibrillation, highlighting important safety co
A comprehensive multicenter study reveals frequent neuroimaging abnormalities in children with Noonan syndrome and elucidates their associations with genetic variants and neurological symptoms, enhancing understanding of brain involvement i
This study evaluates the eligibility of children with acute ischemic stroke (AIS) for thrombolysis with tPA, revealing only 19% potential eligibility under current guidelines, and highlights opportunities to reconsider treatment in small-ve
Baseline cortical atrophy within an EOAD-specific brain signature predicts progression from mild cognitive impairment to dementia, providing a valuable MRI biomarker for individualized prognosis in early-onset Alzheimer disease.
The ENCHANTED trial post hoc analysis reveals body weight does not alter alteplase dose effectiveness in acute ischemic stroke, but low body weight independently predicts poorer outcomes without increased hemorrhagic risk.
This exploratory longitudinal study reveals that alongside decreased glucose metabolism, elevated brainstem methionine uptake correlates with consciousness improvement in brain-injured patients, highlighting novel metabolic biomarkers for p
The Vibrance-1 phase 2 trial demonstrates that once-daily oral alixorexton significantly improves wakefulness and reduces cataplexy in narcolepsy type 1, with a favorable safety profile supporting phase 3 evaluation.
This study identifies key nongenetic factors impacting disease onset and severity in hereditary ataxias SCA6 and SCA27B, highlighting environmental exposures and demographics as important modifiers beyond genetic mutations.
Cascade genetic screening in hereditary transthyretin amyloidosis (ATTRv) enables earlier diagnosis and intervention, improving survival and highlighting the need for variant-specific surveillance strategies.
