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Neurology

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Neurology

Bridging Social Determinants of Health and Multidimensional Frailty Among Older Adults: A Domain-Specific Latent Class and Network Analysis

This study explores how economic, educational, healthcare, neighborhood, and social factors link to multiple frailty dimensions in Chinese older adults, highlighting cognition as a key intermediary.

Aug 25, 2026
Critical Care

How Respiratory Mechanics Shapes Ventilator Settings and Outcomes in Acute Brain Injury Patients

This study reveals how respiratory system elastance influences the effects of tidal volume and respiratory rate on outcomes in mechanically ventilated acute brain injury patients, suggesting personalized ventilation strategies based on resp

Aug 24, 2026Sign in to read
Neurology

Smartphone-Based 3D Facial Geometry: A Novel Tool for Objective Assessment and Monitoring of Facial Nerve Palsy

This study demonstrates that high-resolution 3D facial geometry captured via smartphone accurately and objectively quantifies facial nerve palsy severity, enabling continuous grading, early detection, and improved patient monitoring.

Aug 24, 2026
Neurology

Early Escalation of Acute Treatment Reduces Relapse Risk in Pediatric MOG Antibody-Associated Disease

In pediatric myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), escalation of acute immunotherapy beyond steroids at first attack is linked to significantly fewer relapses within one year and mid-term follow-up, highli

Aug 24, 2026
Neurology

Lifelong Risk of De Novo Aneurysm Formation in Young Survivors of Aneurysmal Subarachnoid Hemorrhage: A Four-Decade Perspective

Young survivors of aneurysmal subarachnoid hemorrhage face a lifelong risk of developing new aneurysms, with female sex, smoking, and family history as key risk factors. Smoking cessation reduces this risk, supporting need for lifelong surv

Aug 24, 2026Sign in to read
General Surgery

Mapping Cognitive Load in Novice Surgeons: Insights Into Brain Activation and Performance Under Stress

This study elucidates how escalating cognitive workload affects brain activation in novice surgical residents, revealing distinct neural patterns linked to performance resilience or decline during simulated suturing tasks.

Aug 24, 2026
Clinical Updates

Feasibility and Patient-Centered Insights from a Pilot Trial of Home-Based Cognitive Training for Cognitive Impairment in Gynecologic Cancer Survivors

This review synthesizes evidence on home-based cognitive training feasibility, adherence, and patient experiences in gynecologic cancer survivors with CRCI, highlighting clinical implications and directions for optimized intervention design

Aug 24, 2026
Critical Care

Individualized vs Standard Blood Pressure Control During Mechanical Thrombectomy for Acute Ischemic Stroke: Insights from the DETERMINE Randomized Clinical Trial

A randomized clinical trial comparing individualized versus standard blood pressure control during mechanical thrombectomy for ischemic stroke showed no significant difference in 90-day functional outcomes or safety.

Aug 24, 2026Sign in to read
Clinical Updates

Paternal Valproate Exposure and Offspring Neurodevelopmental Outcomes: A Comprehensive Review of Current Evidence

This review synthesizes evidence on paternal valproate exposure and offspring neurodevelopmental risks, highlighting recent large cohort data that challenge prior concerns of increased neurodevelopmental disorders or congenital malformation

Aug 24, 2026Sign in to read
Diabetes & Endocrinology

Distinct Complication Patterns in Lean Versus Overweight African Adults with Type 2 Diabetes: Implications for Targeted Management

African adults with type 2 diabetes who are lean exhibit distinct complication profiles characterized by higher retinopathy and stroke risk but lower hypertension and cardiovascular disease risk compared to their overweight/obese counterpar

Aug 24, 2026Sign in to read
Cardiology

Association of Clonal Hematopoiesis With Silent Brain Lesions and Cognitive Decline in Patients With Atrial Fibrillation: An Integrative Review

Clonal hematopoiesis (CHIP) significantly associates with increased silent brain lesions and progressive cognitive decline in atrial fibrillation patients, highlighting a novel neurovascular risk factor with implications for patient managem

Aug 24, 2026Sign in to read
General Surgery

Navigating Surgical Decisions in Dementia: Challenges and Clinical Insights

Clinicians face multifaceted challenges during surgical decision-making for patients with dementia, including difficulties in dementia recognition, reliance on caregivers, and lack of evidence-based guidelines, underscoring the need for imp

Aug 23, 2026
General Surgery

Navigating Surgical Decisions in Patients with Dementia: Clinician Challenges and Insights

This article explores the complex challenges clinicians face in surgical decision-making for patients with dementia, highlighting issues with dementia identification, caregiver roles, and the influence of dementia on surgical outcomes.

Aug 22, 2026Sign in to read
Cardiology

Beyond Stenosis: How Carotid Plaque Calcification Patterns on CTA Predict Stroke Risk

This study reveals that the characteristics of carotid plaque calcifications on CTA scans correlate with stroke symptoms beyond traditional stenosis severity, offering improved risk stratification for carotid artery disease.

Aug 22, 2026
Neurology

Baseline Ischemic Burden Influences Tenecteplase Benefit Before Thrombectomy in Acute Stroke: Insights from the BRIDGE-TNK Trial

A post hoc analysis of the BRIDGE-TNK trial reveals that intravenous tenecteplase before endovascular thrombectomy significantly improves functional independence in acute large-vessel occlusion stroke patients with extensive baseline ischem

Aug 22, 2026
Neurology

Paramagnetic Rim Lesions as Predictors of Progression in Multiple Sclerosis: Insights from a 5-Year Longitudinal Study

Paramagnetic rim lesions detected via MRI are associated with increased risk of disability progression independent of relapse activity and accelerated brain atrophy in multiple sclerosis, highlighting their role as prognostic biomarkers for

Aug 22, 2026
Neurology

Enhancing Vestibular Migraine Rehabilitation with Virtual Reality: A Randomized Controlled Trial

This randomized trial demonstrates that adding virtual reality-based vestibular rehabilitation to home exercises significantly improves symptom severity and dynamic postural control in vestibular migraine patients.

Aug 21, 2026
Neurology

Rethinking Meningioma Management: Incidence Surge Amid Stable Treatment and Extensive Imaging Surveillance

Between 2010 and 2023 in Denmark, meningioma incidence doubled while treatment rates remained steady. Extensive follow-up imaging was common but rarely altered management, highlighting opportunities for risk-adapted surveillance protocols.

Aug 21, 2026
Cardiology

Colchicine for Secondary Prevention After Stroke According to the Presence of Atherosclerosis: Clinical Evidence and Implications

This review synthesizes evidence on colchicine’s efficacy in secondary stroke prevention, emphasizing the impact of concomitant atherosclerosis on outcomes from the CONVINCE trial and meta-analyses.

Aug 21, 2026
Cardiology

Optimizing LDL-C Reduction Strategies in Ischemic Stroke: Impact of Achieving ≥50% LDL-C Reduction from Baseline

Achieving a ≥50% reduction in LDL-C from baseline independently reduces recurrent cardiovascular events post-ischemic stroke, suggesting that combining relative and absolute LDL-C targets improves long-term outcomes.

Aug 21, 2026
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