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A multi-center study demonstrates that preoperative ctDNA detection significantly outperforms traditional clinical criteria in predicting nodal upstaging and survival outcomes for patients with clinical stage I/II ESCC, potentially redefini
The 5-year follow-up of the LASSO randomized clinical trial demonstrates that while laparoscopic adhesiolysis offers short-term recovery benefits, it provides no significant long-term advantage over open surgery regarding SBO recurrence, in
A multicenter randomized clinical trial demonstrates that selective calcium supplementation based on early postoperative PTH levels is as effective as routine prophylaxis in preventing hypocalcemia after total thyroidectomy, offering a stra
A population-based study in England reveals that correcting socioeconomic and clinical inequalities in the use of minimally invasive surgery for colon cancer significantly reduces hospital stays and 1-year mortality, highlighting a critical
A post-hoc analysis of the nationwide PORSCH trial reveals that algorithm-based care for early recognition and management of postoperative complications significantly improves long-term overall survival in patients undergoing pancreatic res
A JAMA study demonstrates that Rapid Ultraoxygenated Recovery (REUP) enables successful DCD heart transplantation without preimplant reanimation, achieving 96% survival despite extended ischemic times and older donors, potentially offering
A systematic review and meta-analysis of over 400,000 patients reveals that while older adults face higher relative risks for nerve injury and hematoma following thyroidectomy, the absolute risk remains low, confirming the procedure’s
The DALI cohort study reveals that while current DOAC interruption protocols are generally effective, 13.1% of apixaban users maintain levels ≥30 ng/mL before surgery. However, these residual levels did not correlate with increased surgical
A large-scale study of Swiss surgical patients reveals that nearly 20% of those experiencing major complications die in-hospital. Critical variations between institutions suggest that over 1,000 deaths could be avoided through improved orga
A national Swiss study reveals that 1 in 5 surgical patients experiencing major complications die, with nearly 15% of these deaths linked to institutional performance gaps rather than patient risk factors.
This cohort study demonstrates that postoperative sleep architecture is differentially disrupted based on surgical risk. High-risk procedures cause prolonged deficits in REM and deep sleep, which are associated with increased complications,
The LEGenD-1 trial demonstrates that intramuscular HGF gene therapy (AMG0001) significantly reduces healing time for neuroischemic ulcers in patients with moderate chronic limb-threatening ischemia, offering a potential nonsurgical therapeu
A randomized clinical trial demonstrates that wearable transcutaneous electrical acupoint stimulation (TEAS) provides superior symptom relief and significantly lower relapse rates compared to intravenous metoclopramide in managing moderate
An in-depth look at the 2025 WSES Jerusalem Guidelines for acute appendicitis, focusing on new diagnostic scoring, the 24-hour surgical window, and optimized nonoperative management strategies.
A 5-year prospective study from the Teen-LABS cohort reveals that early post-operative complications are a primary driver of long-term healthcare utilization in adolescents following bariatric surgery, emphasizing the need for targeted long
A two-center observational study highlights significant risks, including a 40% 30-day mortality rate, when performing endovascular aortic arch repair in patients with a native ascending aorta diameter exceeding 38 mm.
A population-level study of nearly 500,000 patients reveals that dedicated emergency general surgery (EGS) models significantly improve survival and reduce complications for high-risk patients compared to traditional on-call models, suggest
A cross-sectional study reveals that while 85% of Americans support licensing internationally trained surgeons to address workforce shortages, nearly 80% are reluctant to personally undergo surgery by them, highlighting a significant gap be
The 10-year follow-up of the APPAC trial demonstrates that antibiotic therapy remains a safe and effective alternative to appendectomy for uncomplicated acute appendicitis, with over 60% of patients successfully avoiding surgery for a decad
A decision analytical model based on the SANO trial suggests that while active surveillance offers short-term quality-of-life benefits, standard esophagectomy remains superior for maximizing long-term survival and quality-adjusted life-year
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