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A concise overview of the newly developed Core Outcome Set for healthy aging in primary care—12 prioritized outcomes to standardize evaluation of health-promotion interventions and improve comparability across studies and programs.
A concise guide to the newly published Core Outcome Set for Post COVID-19 Condition (COS‑PCC): the nine prioritized outcomes, recommended measurement instruments, timing considerations, and implications for research and care.
An international Delphi consensus defined a Core Outcome Measurement Set (COMS) for dengue trials to harmonise outcome selection and measurement across settings, improving comparability and evidence synthesis.
This review synthesizes evidence from Rwanda’s 2024 Marburg virus disease outbreak, highlighting epidemiologic characteristics, clinical presentations, investigational therapeutics, and vaccine deployment strategies that contributed t
This review synthesizes 24-month follow-up data on monkeypox virus infection and MVA-BN vaccination, detailing durable immunity post-infection, comparative antibody kinetics, and clinical sequelae, informing future vaccination strategies an
In a randomized, placebo-controlled phase 1 trial in Uganda, a single intramuscular dose of ChAdOx1 RVF (adenovirus-vectored) was well tolerated and induced rapid T-cell responses and neutralising antibodies, supporting further evaluation o
A nationally representative serosurvey and transmission modelling study in Bangladesh estimates low population-level JEV exposure but large numbers of infections annually; spatially targeted vaccination would be most efficient, though not c
A nationwide French multicentre cohort (ORIGAMI) documents a substantial 2023–24 paediatric hospitalisation surge from Mycoplasma pneumoniae, identifies older age, asthma, comorbidity and erythema multiforme as ICU risk factors, and highlig
This comprehensive review synthesizes recent evidence on brand-specific influenza vaccine effectiveness (VE) among adults aged ≥65 in Denmark, Finland, and Sweden during the 2024-2025 season, underscoring heterogeneous VE profiles and the c
A Finnish registry cohort (n=913,149) found that exposure to same-grade schoolmates’ self-harm modestly increased later self-harm risk (HR 1.05), with the largest effect around age 16 (HR ~1.45), suggesting time-limited social transmi
A nationwide ECHO analysis found wildfire-specific PM2.5 exposure was associated with increased odds of preterm birth in the US West, with stronger effects for higher concentration, longer smoke waves, and mid-to-late pregnancy exposures.
The Infectious Diseases Society of America now recommends annual high-dose or adjuvanted influenza vaccine and a single RSV dose for most immunocompromised persons; timing around immunosuppression and household immunization are emphasized.
A multinational time-series analysis of 11.4 million admissions found that higher neighbourhood greenness (NDVI) was linked to lower hospital admissions for mental disorders overall, with heterogeneity across countries and disorder types an
A multinational time-series study across nine countries found increased short-term mortality after tropical cyclones for multiple causes — highest for renal disease and injuries — with larger effects in deprived and cyclone-naïve communitie
A phase 3 trial of Pfizer’s quadrivalent modified mRNA influenza vaccine (n≈18,476) showed 34.5% relative efficacy vs a licensed inactivated vaccine for laboratory-confirmed influenza (A strains) with higher reactogenicity but low rates of
A Los Angeles County quality-improvement study found that regulatory approval allowing an inpatient hemodialysis unit to provide transitional outpatient dialysis to uninsured patients initiating hemodialysis was associated with a substantia
This study explores how changes in residential environments affect childhood BMI, focusing on air pollution, built environment, and socioeconomic factors across cohorts in the Netherlands, Sweden, and Czech Republic.
A Medicare claims study of 19,692 balloon sinus dilations found 15% lacked a CT within one year; 31.8% of otolaryngologists were outliers, with a small group accounting for most missed imaging, highlighting gaps in adherence to preoperative
A cross-sectional analysis (FDA approvals 2015–2018) found that most countries hosting pivotal trials lack timely market authorization for tested medicines, especially lower- and middle-income countries—raising ethical, regulatory, and poli
A 24‑week, community-based multicomponent frailty intervention in rural Korea was associated with 6.5 additional months free from death or long‑term care eligibility and ~$7,700 per-person NHIS savings over 66 months, suggesting durable cli
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