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Evaluating Dual Use: How E-Cigarettes Influence Real-Time Smoking Reduction in Combustible Cigarette Users
Dual use of e-cigarettes and combustible cigarettes reduces smoking frequency and increases smoke-free days, as shown in a large U.S. randomized trial with adults who smoke.
Does Increasing Cigarette Use Stabilize Mood? Insights from a 6-Year Real-Time Adolescent Study
Longitudinal observational data reveal that as adolescents increase cigarette use, their immediate post-smoking mood stabilizes, with boys showing stabilization in background mood as well.
Decoding 10-Year Cardiovascular Risk in Ethiopia: The Impact of Individual and Community Factors
A population-based study in Ethiopia reveals 7.3% of adults aged 40-69 face a 10-year cardiovascular disease risk ≥10%, influenced by urban residence, education, physical activity, employment status, and climate factors.
Global Shifts in Pulmonary Embolism Mortality: A 2001-2023 WHO Database Analysis
Analysis of WHO data reveals declining global pulmonary embolism mortality overall, with marked differences by region and income, highlighting urgent needs in lower-middle-income countries.
International Trends in Biliary Tract Cancer Mortality from 2000 to 2022: A Comprehensive WHO Database Analysis
This observational study reveals stable global biliary tract cancer mortality rates over two decades, with a striking rise in intrahepatic cholangiocarcinoma mortality, underscoring the need for targeted screening and management strategies.
Michigan’s MI-SIGHT Telemedicine Program: Enhancing Glaucoma Screening, Vision Outcomes, and Cost-Effectiveness in Underserved Communities
The MI-SIGHT telemedicine program significantly improves vision and eye health outcomes by providing glaucoma and eye disease screening with care navigation in community health centers, demonstrating high satisfaction and cost-effectiveness
Maternal Bivalent Prefusion F RSV Vaccine Significantly Reduces Infant Hospitalisation in UK: Real-World Evidence from a Multicentre Study
A UK-wide multicentre study shows maternal bivalent RSV prefusion F vaccination reduces infant hospitalisation for RSV-associated ALRI by up to 72%, confirming real-world effectiveness matching clinical trials.
Socioeconomic Disparities in Intrahepatic Cholangiocarcinoma in Sweden: Incidence, Treatment, and Survival in a Universal Healthcare Context
A nationwide Swedish study reveals significant socioeconomic disparities in intrahepatic cholangiocarcinoma incidence, treatment access, and survival despite universal healthcare coverage, underscoring persistent health inequities linked to
The younger you smoke, the earlier you age
Early-life tobacco exposure, including in utero and childhood smoking initiation, significantly accelerates biological aging and is partially mediated by inflammation markers, highlighting critical windows for prevention.
Depression and Anxiety Rates Increased Among Racial Groups During the Pandemic
A survey reveals significant increases in depression and anxiety rates among various racial groups during the COVID-19 pandemic, highlighting ongoing racial health disparities.
Global Patterns and Challenges of Antibiotic Prescribing in Primary Care: A Comprehensive Systematic Review and Meta-Analysis
A global meta-analysis reveals that over 40% of primary care prescriptions contain antibiotics, with more than half being inappropriate, highlighting urgent needs for improved antimicrobial stewardship worldwide.
Symptomatic Respiratory Disease and COVID-19 Testing Among Healthcare Workers: Insights from the Post-Pandemic Era in Ireland
A recent Irish study reveals that 6 in 10 healthcare workers with respiratory symptoms test for COVID-19, while vaccination coverage remains low, highlighting ongoing risks and the need for enhanced infection control and vaccination strateg
Diverging Pediatric Recommendations on COVID-19 Vaccination: The AAP Advocates Routine Immunization for Young Children Amid Federal Policy Shift
The American Academy of Pediatrics recommends COVID-19 vaccination for all young children aged 6-23 months, diverging from current CDC policies that advise shared decision-making for healthy children. This review analyzes epidemiologic data
Digital Therapeutics in Suicide Prevention: Evidence and Clinical Implications of a Smartphone-Based CBT Intervention
Smartphone-delivered cognitive-behavioral therapy (CBT) via a digital therapeutic app significantly reduces recurrent suicide attempts and sustains reduction in suicidal ideation among adults with prior suicide attempts.
Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis
This review integrates data from over two million individuals globally, showing that absence of five key cardiovascular risk factors at age 50 confers a life expectancy advantage exceeding a decade, with midlife modification of hypertension
Drivers of Human Papillomavirus Vaccine Uptake in Migrant Populations and Interventions to Improve Coverage
This systematic review reveals multifaceted barriers to HPV vaccine uptake among migrants globally, with overall low coverage. It highlights individual, social, and systemic factors influencing uptake and delineates effective culturally tai
Australia Report: Seven Major Challenges of Safe and Reliable Medical Artificial Intelligence in Legislation and Regulation
This report outlines the challenges and recommendations for implementing AI in healthcare while ensuring safety and responsibility in Australia.
Evaluating Salt Warning Labels to Reduce High Salt Consumption in UK Out-of-Home Food Sector: Evidence from Online and Real-world Randomised Controlled Trials
UK trials show salt warning labels on packaged foods and menus effectively increase awareness and discourage high salt intake, offering a promising policy to combat cardiovascular risk associated with excessive salt consumption.
Long-term Safety and Efficacy of Rabies Monoclonal Antibody and Vaccine for Post-Exposure Prophylaxis: Insights from a Phase 4 Trial in India
A phase 4 randomized trial demonstrates that combining rabies monoclonal antibody with vaccine in category 3 exposures is safe, immunogenic, and effective in preventing rabies up to one year post-exposure.
Workplace Violence in Urban and Rural Hospitals: A Growing Threat with High Costs
Workplace violence in American hospitals causes significant trauma, financial costs, and operational challenges, affecting both urban and rural hospitals equally, despite differences in available resources. Prevention and trauma-informed re
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