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Microplastics detected in thyroid tissues show higher concentrations in autoimmune thyroiditis patients, suggesting a potential environmental link to thyroid autoimmunity.
A cohort study reveals persistent ethnic disparities in type 2 diabetes risk, with migration status and mental health conditions as independent contributors, highlighting unmet needs in addressing structural determinants of health inequalit
Brief, intermittent bouts of moderate- to vigorous-intensity physical activity during daily routines may significantly reduce the risk of type 2 diabetes in adults who do not engage in leisure-time exercise.
The PURE study reveals significant global disparities in heart failure incidence and mortality, with hypertension as the leading modifiable risk factor, highlighting the need for targeted prevention and treatment strategies.
A national study reveals significant state-level and urban-rural variations in opioid prescribing following toothache diagnoses, with 15 states exceeding the national average and rural areas showing slightly lower prescription rates.
A study of 1,454 older adults with metabolic syndrome reveals that long-term exposure to air pollutants like black carbon, PM2.5, and NO2 is associated with increased fat mass and decreased lean mass, persisting over three years, particular
A new hierarchical algorithm identifies hemorrhage, hypertensive disorders, and infection as the most common underlying conditions for severe maternal morbidity, differing significantly from causes of maternal mortality.
A study reveals significant variability in ALSFRS-R analysis methods across 45 ALS trials, impacting treatment effect estimates and increasing false-positive risks, with implications for clinical decision-making and drug development.
A 36-year prospective study demonstrates that cumulative BMI burden from childhood to adulthood significantly elevates risks of metabolic multimorbidity, with distinct life-stage patterns and sex-specific vulnerabilities.
A cohort study of over 1 million cancer patients revealed significant reductions in 1-year survival rates during 2020-2021 compared to pre-pandemic trends, with an estimated 17,390 excess cancer deaths attributable to pandemic-related care
The Systems Analysis and Improvement Approach for Mental Health (SAIA-MH) significantly improved functional outcomes, medication adherence, and appointment attendance in Mozambican outpatient clinics, offering a scalable model for low-resou
A proactive digital mental health platform improved mental health outcomes for health care workers, with notable benefits for Black and female participants in work productivity and sustained depression reduction.
A randomized trial found that a $80 monthly produce prescription did not significantly improve HbA1c levels or reduce healthcare utilization in diabetic patients at risk of food insecurity.
A novel statistical model predicts chronic immune thrombocytopenia (ITP) in children at diagnosis, using age, sex, immunoglobulin levels, and lab values, offering early clinical guidance.
In a large survey of adult ear piercings, auricular cartilage piercings had higher complication and removal rates than lobule piercings, reinforcing the need for careful counseling and informed consent.
In a large Medicare study, hospitals under Maryland’s global budget model showed modest but significant improvements in cancer surgery outcomes, driven by fewer complications and shorter stays, with lower inpatient spending.
In two large U.S. cohorts, greater adherence to healthy dietary patterns—especially DASH—was associated with less subjective cognitive decline and slightly better objective cognition.
A novel matching approach using 911 call time and patient characteristics can effectively identify duplicate EMS responses, enabling more accurate patient-level inferences from response-based datasets with 100% sensitivity and up to 98.6% s
This qualitative study explores systemic barriers faced by underrepresented scholars in biomedical research, revealing challenges in academic culture, external pressures, and strategies for resilience through interviews with 78 early-career
A cross-sectional analysis of health technology assessments across G20 nations reveals significant disparities in access to CAR T-cell therapies, with only 48% of approved indications recommended for reimbursement and a median 1.54-year del
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