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A large US claims-based cohort suggests that most open-angle glaucoma suspects have modest annual conversion risk after the first year, and that age- and treatment-informed surveillance intervals may help tailor follow-up intensity.
A multicenter prospective cohort study suggests that substantial surgeon social jet lag, but not midsleep variability alone, is associated with higher 30-day major adverse event risk after surgery and correlates with surgeon burnout.
In a large prospective U.S. cohort, severe maternal morbidity did not reduce breastfeeding initiation, but it was associated with lower odds of breastfeeding beyond 6 months and of exclusive breastfeeding.
A national U.S. study found that patients with epilepsy from rural counties had worse hospital outcomes, including higher mortality, more status epilepticus, longer stays, and less EEG use, highlighting access-related disparities.
A large French cohort study found that higher exposure to several food coloring additives was associated with increased incidence of type 2 diabetes, highlighting the need for further research and possible reevaluation of some additives.
In a nationwide Medicare cohort, chronic wildfire smoke PM2.5 exposure was associated with a modest but significant increase in incident stroke, with stronger effects over longer exposure windows.
A large multicenter study found that emergency department triage mismatches were linked to small delays in care and longer stays, especially for overtriaged patients. Better use of patient history may improve triage accuracy.
Mailed outreach improved colorectal cancer screening in community health centers, with FIT-DNA outperforming FIT. However, colonoscopy follow-up after abnormal stool tests remained low despite navigation support.
This review synthesizes the American Thoracic Society’s 2026 research statement on the US Air Quality Index, identifying critical knowledge gaps and prioritizing five research domains to enhance its effectiveness for patients with res
A large U.S. study found that a contrast sensitivity score of 1.60 logCS marks the point where older adults are more likely to experience everyday vision disability, even when standard visual acuity may seem acceptable.
In the HUNT Study, higher midlife waist-to-height ratio and BMI predicted higher late-life plasma p-tau217 and biomarker-verified Alzheimer dementia, whereas higher adiposity in late life was associated with lower biomarker levels and lower
A small randomized trial found that blocking IL-6 with tocilizumab showed promising, clinically meaningful trends for inflammation-related, hard-to-treat depression, especially for somatic symptoms, fatigue, anxiety, and quality of life, th
A survey study found three distinct patient preference patterns for anticoagulation after hip or knee replacement: clot-prevention focused, balanced, and cost-focused. These differences may help personalize postoperative blood thinner choic
A survey study found three distinct patient preference patterns for anticoagulation after hip or knee replacement, highlighting the importance of shared decision-making based on clot risk, bleeding risk, and cost.
ACP warns that private equity in health care can raise costs, weaken clinical autonomy, and affect access and quality, calling for stronger transparency, oversight, and protections for physicians and patients.
A new multimodal study links regular physical activity to lower chronic pancreatitis risk and identifies muscle-derived extracellular vesicles as a plausible mechanism limiting pancreatic inflammation, fibrosis, and ferroptosis.
A large multi-cohort genome-first study found similar prevalence of pathogenic FH variants across ancestries, but more VUSs and greater LDL-C and myocardial infarction risk among African ancestry individuals, highlighting likely underclassi
A large Danish genetic study suggests recurrent CNVs and polygenic scores provide complementary psychiatric risk information, with polygenic scores often identifying more at-risk individuals and potentially modifying CNV-associated risk.
A qualitative VA study found that COVID-19 reduced trainee learning opportunities and heightened safety concerns, yet trainees contributed substantially to care delivery, telehealth expansion, patient support, and local pandemic planning.
A 2010-2023 analysis found that CMS enforcement against Medicare Advantage plans was highly variable, usually limited to modest monetary penalties, and more common among lower-rated contracts serving more socially vulnerable beneficiaries.
