Psychiatry
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Impact of Screening and Care for Emotional and Cognitive Problems on Post-Ischemic Stroke Outcomes: Insights from a Dutch Multicenter Cluster-Randomized Trial
A multicenter trial assessing emotional and cognitive screening post-ischemic stroke found no improvement in societal participation at 1 year, though modest early benefits in anxiety and quality of life were noted.
Risk of New-Onset and Recurrent Depression and Anxiety Among Patients With Hidradenitis Suppurativa
Patients with hidradenitis suppurativa face a higher risk of first-time depression and anxiety, regardless of disease severity, highlighting the need for comprehensive psychiatric care.
Elevated Risk of Depression and Anxiety in Hidradenitis Suppurativa: Implications Beyond Disease Severity
Patients with hidradenitis suppurativa face a significantly increased risk of new-onset depression and anxiety, independent of disease severity, highlighting the need for universal psychiatric assessment in this population.
Reducing TV Time and Boosting Physical Activity: A Key Strategy to Prevent Depression in Middle-Aged Adults
A large Dutch cohort study reveals that substituting TV-watching time with physical activities or sleep significantly lowers major depression risk, especially in middle-aged adults, highlighting the mental health benefits of an active lifes
Novel Benzodiazepines Intensify Opioid Overdose Severity: A Multicenter ED Study
Novel benzodiazepine coexposure in opioid overdoses significantly increases the risk of mechanical ventilation and naloxone nonresponse, highlighting a critical challenge in emergency care management.
ADHD Drugmakers Double Marketing Spending to Clinicians: Implications for Prescribing and Patient Care
Pharmaceutical companies have significantly increased marketing payments to clinicians for ADHD medications, particularly targeting advanced practice clinicians. The impact of this trend on prescribing patterns and clinical benefits remains
Eat Your Way to a Better Mood and Cancer Prevention: 9 Foods That Boost Mental and Physical Health
Discover nine brain- and body-friendly foods that improve mood, reduce inflammation, stabilize blood sugar, and offer potential cancer-protective benefits, supporting both emotional well-being and long-term health.
Preoperative Anxiety as a Key Predictor of Postoperative Delirium: Insights from a Year-Long Cohort Study
A prospective study reveals that nearly 20% of surgical patients experience postoperative delirium in the PACU, with elevated preoperative anxiety significantly increasing this risk. Implementation of a brain health care bundle improves man
Unraveling the Link Between Gastrointestinal Disorders and Sleep Problems: The Role of Depression
This article explores how gastrointestinal diseases are linked to sleep disturbances, highlighting depression as a partial mediator and emphasizing the importance of addressing both gut and psychological health to improve sleep quality.
Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment
Mental disorders currently diagnosed symptomatically can be redefined using biology-informed frameworks integrating biological, behavioral, and environmental data. The Precision Psychiatry Roadmap aims to harmonize global research and clini
Unraveling Chronic Stress: The Role of Gut Dysbiosis and Vitamin B6 Metabolism in Stress-Related Brain Disorders Independent of Cortisol
Recent evidence reveals gut dysbiosis-induced vitamin B6 metabolic disturbances as a novel, cortisol-independent mechanism driving chronic stress-related abnormal behaviors and inflammation, highlighting probiotic and vitamin B6 supplementa
Optimizing Smoking Cessation in Major Depressive Disorder: Varenicline Outperforms Bupropion and Nicotine Patch with Comparable Safety
This analysis reveals that varenicline is the most effective and safe pharmacotherapy for smoking cessation in individuals with current or past major depressive disorder, outperforming bupropion and nicotine patches with no increased neurop
Evaluating the Role of AI Tools in Pharmacy Students’ OSCE Performance and Anxiety: Insights from a Randomized Controlled Trial
A randomized trial assessing AI-generated study materials revealed no significant impact on pharmacy students’ objective structured clinical examination scores or test anxiety levels, highlighting the need for further research on long-term
Enhancing Depression Care in College Students: AI Chatbots with Social Cues Show Superior Effectiveness
A 16-week randomized trial demonstrates that AI chatbots with high-social-cue design significantly reduce depression and anxiety symptoms in college students compared to text-only chatbots, improving adherence, satisfaction, and therapeutic
Harnessing Slow-Wave Sleep for Internet Gaming Disorder: Efficacy of Closed-Loop Auditory Exposure
Closed-loop auditory exposure during slow-wave sleep significantly reduces craving and playtime in Internet Gaming Disorder by modulating sleep spindle power, offering a novel, non-invasive therapeutic strategy.
Reducing Carcinogen Exposure in Smokers with Serious Mental Illness: Insights from a Randomized Controlled Trial of E-Cigarette Provision
This RCT demonstrates that disposable e-cigarettes significantly reduce carcinogen levels short-term among smokers with serious mental illness, underscoring the need for behavioral support to sustain harm reduction.
Esketamine in Lung Cancer Patients with Major Depression: Efficacy for Smoking Cessation and Treatment-Resistant Depression
This review synthesizes evidence from a randomized trial and real-world studies showing esketamine’s efficacy and safety in smoking cessation among lung cancer patients with MDD, as well as in treatment-resistant depression, highlighting co
Does Increasing Cigarette Use Stabilize Mood? Insights from a 6-Year Real-Time Adolescent Study
Longitudinal observational data reveal that as adolescents increase cigarette use, their immediate post-smoking mood stabilizes, with boys showing stabilization in background mood as well.
Evaluating a Proactive E-Health Intervention for Co-occurring At-Risk Alcohol Use and Depressive Symptoms: Adherence, Reach, and Two-Year Outcomes
This RCT assessed a proactive e-health intervention for patients with at-risk alcohol use and depressive symptoms, showing high adherence but only small, non-significant improvements at 12 months and no lasting effects at 24 months.
Clozapine and Infection Risk in Schizophrenia: Insights from a Hong Kong Population Study
This study reveals an increased risk of infections among schizophrenia patients treated with clozapine compared to olanzapine, highlighting the need for vigilant infection monitoring and preventive care.
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