Psychiatry
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Three Minutes of ‘Small Talk’ That Keep Love Alive: How ‘Meaningless’ Chatter Boosts Dopamine and Deepens Bonds
Brief daily low-stakes exchanges—‘the clouds look like cotton candy’—build safety, activate reward circuits and sustain intimacy. Science explains why micro-connections matter and how clinicians and couples can use a 3‑minute practice to st
Simvastatin Added to Escitalopram in Obese Patients With Major Depression: A Rigorous RCT Shows No Antidepressant Benefit Despite Improved Cardiometabolic Markers
A multicenter double-blind RCT (n=160) found that 12 weeks of simvastatin (40 mg) added to escitalopram did not improve depressive symptoms versus placebo, although LDL, total cholesterol, and CRP were reduced.
Therapist-Guided Internet CBT Cuts Bulimia Episodes: A Japanese Randomized Trial with Promising Clinical Implications
A multicenter randomized trial in Japan found that a 12-week therapist-guided internet-based CBT program significantly reduced weekly bingeing and compensatory episodes in women with bulimia nervosa versus usual care (adjusted mean differen
Smartphone CBT for Inpatient Suicide Risk: Promising Signal for Those With Prior Attempts, But Primary Outcome Missed
A multisite RCT of a 12‑module smartphone CBT intervention for psychiatric inpatients did not change time to first suicide attempt overall, but sustained reductions in suicidal ideation and reduced recurrent attempts among patients with pri
Irregular Sleep Patterns: Unveiling Hidden Health Risks Across Metabolic, Cardiovascular, and Mental Domains
Recent studies link irregular sleep to higher risks of type 2 diabetes, cardiometabolic diseases, all-cause mortality, and depression. Consistent sleep timing may offer crucial protection against these adverse outcomes.
The Power of Letting Go: A Psychology-Based Approach to Emotional Healing
Discover how embracing the ‘Let Them’ philosophy can enhance emotional resilience and improve interpersonal relationships.
Stress and Weight: Does Pressure Make You Gain or Lose Pounds?
Explore how stress impacts body weight, causing some to gain while others lose pounds due to hormonal and neural responses.
Shopping Addiction: When Consumerism Takes a Toll on Mental Health
Explore the science behind shopping addiction, its impact on mental health, and practical solutions to manage compulsive buying behaviors.
Do Safety Planning Interventions Reduce Suicide Risk in Adolescents? Insights from a Systematic Review and Meta-Analysis
Recent meta-analysis finds no significant benefit of standalone safety planning interventions in reducing suicidal ideation or behavior among adolescents, highlighting the need for more robust research.
Empowering Parents: Acceptance and Commitment Therapy for Children With Asthma and ADHD
A randomized clinical trial demonstrates that an Acceptance and Commitment Therapy-based parenting program reduces health care use, improves asthma control, and alleviates ADHD symptoms in children with both conditions.
Paternal Perinatal Depression and Child Development: Unveiling an Overlooked Risk for the Next Generation
A systematic review and meta-analysis reveals that paternal perinatal depression, anxiety, and stress are associated with adverse developmental outcomes in children, highlighting the need for targeted interventions for fathers during the pe
Your Gut, Your Mood: How the ‘Second Brain’ Can Beat the Blues
Explore how the gut, often called the ‘second brain,’ influences mood and mental health, and learn ways to nurture this connection for better emotional well-being.
Dissecting Depression in Diabetes: Distinct Links of Somatic and Cognitive Symptoms with Inflammation and Insulin Resistance
New GRADE sub-study reveals that somatic symptoms of depression, not cognitive-affective symptoms, are chiefly associated with inflammation and insulin resistance in type 2 diabetes, highlighting a pathophysiological bridge for targeted int
Long-Acting Oral Weekly Risperidone (LYN-005): Translating Pharmacokinetic Equivalence to Clinical Opportunity in Schizophrenia
Weekly LYN-005 demonstrated pharmacokinetic equivalence to daily risperidone, sustained therapeutic levels, and manageable safety in clinically stable patients, offering a novel option to address non-adherence in schizophrenia.
Semaglutide for Weight Management in Clozapine-Treated Schizophrenia: Results from the COaST Phase 2 RCT in Australia
Semaglutide significantly reduced body weight without impacting psychotic symptoms or clozapine levels in people with schizophrenia and obesity on clozapine therapy.
E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns
Recent trials show no significant difference in smoking cessation rates between e-cigarettes and combination nicotine replacement therapy among patients discharged from inpatient substance use withdrawal services. Longitudinal analyses reve
Comparative Analysis of Virtual Reality Therapies for Psychotic Symptoms: Auditory Hallucinations vs. Persecutory Delusions
Two randomized controlled trials evaluated immersive VR therapies targeting auditory verbal hallucinations and persecutory delusions in schizophrenia and psychosis, revealing modest benefits for hallucinations but no superior effect for cog
Pramipexole Augmentation in Treatment-Resistant Unipolar Depression: A UK Multicentre Randomised Trial
A UK multicentre, double-blind, placebo-controlled trial demonstrates that pramipexole augmentation at 2.5 mg reduces depressive symptoms in treatment-resistant unipolar depression at 12 weeks, with some adverse effects noted, supporting it
Opioid Prescribing Down, Imaging Steady: Patterns in US ED Management of Low Back Pain, 2016–2022
A large national study shows opioid prescribing for ED low back pain fell sharply from 2016 to 2022, while radiograph use remained high and unchanged.
US News & World Report 2025-2026 Rankings: The Top US Psychiatric Hospitals and Their Clinical Impact
Massachusetts General Hospital leads the 2025-2026 US News psychiatric hospital rankings. Rankings highlight excellence in psychiatric care, but methodological nuances and clinical implications warrant closer examination.
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