General Surgery
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Superior Durability of Dedicated Balloon-Expandable Bridging Stents in BEVAR: Insights from the BeGraft Peripheral Plus Study
A large-scale multicenter study confirms that the BeGraft Peripheral Plus (BGP+) bridging stent graft offers exceptional technical success and high two-year patency rates in branched endovascular aortic repair (BEVAR), establishing it as a
Endoscopic Radial Artery Harvesting Superior to Open Technique for Hand Function and Neurologic Protection in CABG
A randomized trial reveals that endoscopic radial artery harvesting for CABG leads to better patient-reported hand function and significantly fewer neurologic deficits compared to the traditional open technique, potentially redefining the s
Predicting Post-Hepatectomy Liver Failure with the PILOT Architecture: Integrating Liver Regeneration Biomarkers and Time-Phased Machine Learning
The novel PILOT machine learning architecture integrates time-phased perioperative data and regeneration-associated biomarkers to predict post-hepatectomy liver failure within six hours of surgery, significantly outperforming traditional cl
Individualized Driving Pressure-Guided PEEP Fails to Reduce Pulmonary Complications in Open Abdominal Surgery: Results from the DESIGNATION Trial
The DESIGNATION trial demonstrates that driving pressure-guided high PEEP with recruitment maneuvers does not reduce postoperative pulmonary complications compared to standard low PEEP in patients undergoing open abdominal surgery, while si
Vaginal Hysterectomy is No Longer the Uncontested Gold Standard: Evidence from a National 10-Year Analysis
A large-scale analysis of over 83,000 cases reveals that laparoscopic hysterectomy may offer lower complication rates and shorter hospital stays than vaginal hysterectomy, prompting a re-evaluation of current surgical guidelines for benign
Rethinking Radical Surgery: Lobectomy Matches Total Thyroidectomy Outcomes in Intermediate-Risk PTC with Unilateral N1b Disease
A comprehensive meta-analysis suggests that for intermediate-risk papillary thyroid carcinoma with unilateral lateral lymph node metastasis, lobectomy provides oncological outcomes comparable to total thyroidectomy, challenging the necessit
Total Thyroidectomy Superior to Lobectomy for N1b Papillary Thyroid Carcinoma: Longitudinal Data Suggests Age-Dependent Survival Benefits
A large-scale SEER database study reveals that total thyroidectomy significantly improves disease-specific survival for patients with cN1b papillary thyroid cancer. However, this survival advantage is attenuated in younger populations, pote
Prophylactic Tranexamic Acid in General Surgery: Significant Reduction in Major Bleeding Without Thromboembolic Risk
A systematic review and meta-analysis of 26 RCTs reveals that prophylactic tranexamic acid (TXA) significantly reduces blood loss and transfusion needs in general surgery. While safety profiles are favorable, procedural nuances—particularly
Intrathecal Morphine Significantly Enhances Postoperative Recovery Quality Following Laparoscopic Colorectal Surgery
A randomized clinical trial demonstrates that adding low-dose intrathecal morphine to transversus abdominis plane block significantly improves 24-hour recovery quality and reduces opioid consumption in laparoscopic colorectal surgery patien
Beyond Nodal Status: A New Risk Score Predicts Recurrence in Lymph Node-Negative Pancreatic Neuroendocrine Tumors
A multi-center study in JAMA Surgery introduces a validated 13-point risk score to identify recurrence risk in LN-negative PanNET patients, revealing that tumor size, grade, and lymphovascular invasion are critical prognostic drivers even w
Preoperative Total Diet Replacement Safely Reduces Morbidity Risk and Preserves Muscle Mass in Colorectal Cancer Surgery
The CARE feasibility trial demonstrates that a preoperative low-energy total diet replacement program is safe and effective for colorectal cancer patients with excess weight. Significant weight loss was achieved without compromising lean mu
Combined Gastric Electrical Stimulation and Pyloroplasty Achieve Superior Symptom Relief in Refractory Gastroparesis
A randomized clinical trial demonstrates that combining gastric electrical stimulation with pyloroplasty significantly outperforms pyloroplasty alone, providing superior symptom relief and reducing hospitalizations for patients with medicat
Breast Surgery in Metastatic Breast Cancer: Local Control Without Survival Benefit
Randomised trials show breast surgery improves local disease control but not overall survival in de novo metastatic breast cancer.
Prothrombin Complex Concentrate versus Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: Evidence Synthesis from the FARES-II Multicenter Randomized Clinical Trial and Related Studies
This review synthesizes evidence demonstrating that 4-factor prothrombin complex concentrate (4F-PCC) offers superior hemostatic efficacy and safety compared to frozen plasma in managing coagulopathic bleeding during cardiac surgery, suppor
Cryopreserved Versus Liquid-Stored Platelets in Surgical Bleeding: Insights from the CLIP-II Randomized Noninferiority Trial
The CLIP-II trial evaluated dimethyl sulfoxide-cryopreserved platelets with extended shelf-life against conventional liquid-stored platelets in cardiac surgery bleeding, finding noninferiority was not established and cryopreserved platelets
Home-Based Prehabilitation Did Not Reduce Disability or Complications in Older Adults with Frailty: Results of a Pragmatic Multicenter RCT
A pragmatic multicenter randomized trial found that coach-supported, home-based multimodal prehabilitation before elective noncardiac surgery did not reduce 30-day postoperative disability or in-hospital complications in older adults with f
Minimally Invasive Pancreatoduodenectomy Is Noninferior to Open Surgery for 90‑Day Complications but Raises Important Safety and Generalizability Questions
An international randomized trial found minimally invasive pancreatoduodenectomy (mostly robotic) noninferior to open surgery for 90‑day overall complications and modestly faster functional recovery, with lower fistula and wound‑infection r
A 30-Day Mortality Risk Score After Proctectomy for Rectal Cancer: What the NCDB Tells Us and How to Use It
A validated NCDB-derived risk score using age, sex, race, comorbidity, stage, neoadjuvant therapy, length of stay and conversion identifies patients at markedly different 30-day mortality risk after proctectomy (0.8%–4.5%).
International Reference Values for Total Pancreatectomy Show Higher Perioperative Risk Than Pancreatoduodenectomy — Practical Benchmarks for Quality Control
This multicenter study defines international perioperative reference values for total pancreatectomy (TP). Even low‑risk TP carries higher morbidity and mortality than pancreatoduodenectomy; outcomes worsen with vascular resection or conver
Preoperative CT Was Missing in 15% of Balloon Sinus Dilations — Medicare Claims Reveal a Clinically Significant Practice Gap
A Medicare claims study of 19,692 balloon sinus dilations found 15% lacked a CT within one year; 31.8% of otolaryngologists were outliers, with a small group accounting for most missed imaging, highlighting gaps in adherence to preoperative
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