Family Medicine & Nutrition
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Delphi-2M: The AI That Predicts Your Health 20 Years Ahead
A new AI model, Delphi-2M, predicts the risk of over 1,000 diseases up to 20 years in the future with remarkable accuracy, transforming disease prevention and personalized health management.
Why Losing Weight Can Worsen Fatty Liver Disease: The Crucial Role of Balanced Nutrition
Losing weight doesn’t always mean improving fatty liver disease. Discover why strict diets lacking essential proteins can worsen liver health and learn practical dietary strategies to manage and reverse fatty liver effectively.
Nourishing Your Thyroid: How Common Vegetables Support Thyroid Health Through Selenium and More
Thyroid health depends on balanced nutrition, including selenium from everyday vegetables like tomatoes. Discover six key vegetables that support thyroid function and debunk myths about diet and thyroid disease.
From Plate to Progress: Five Scientifically Proven Diets to Help Manage Obesity Effectively
Explore five scientifically supported dietary patterns that aid effective weight loss for individuals struggling with obesity, emphasizing balanced nutrition and sustainable lifestyle changes.
Navigating the 2025 Best Diets: Tailored Eating Plans for Weight Loss, Hypertension, Menopause, and More
The 2025 Best Diets ranking identifies optimal eating plans tailored to specific health needs, such as weight loss, high blood pressure, menopause, and digestive health, emphasizing scientifically backed, sustainable dietary patterns.
Does Drinking More Than 3.5 Cups of Milk Weekly Raise Liver Cancer Risk? Unpacking the Facts Behind the Rumor
A recent Harvard study linking high milk consumption to increased liver cancer risk has sparked confusion. This article clarifies the scientific evidence, dispels misconceptions, and offers guidance on healthy milk consumption based on curr
Impact of Mediterranean Diet and Physical Activity on Bone Health in Older Adults: Insights from the PREDIMED-Plus Trial
A 3-year randomized trial reveals that a weight-loss Mediterranean diet combined with physical activity helps prevent bone mineral density decline in older women with metabolic syndrome.
Time-Restricted Eating in Overweight Adults: Effects on Sleep, Mood, and Quality of Life Remain Neutral
A randomized clinical trial found that different timing schedules of an 8-hour time-restricted eating window combined with Mediterranean diet education did not significantly affect sleep, mood, or quality of life in adults with overweight o
Mediterranean Diet Outperforms Other Dietary Patterns in Reducing Mortality via Inflammatory Pathways: Insights from a Causal Inference Analysis
A causal analysis of nine dietary patterns reveals the Mediterranean diet as most effective in reducing all-cause and cardiovascular mortality, primarily through modulation of inflammatory biomarkers such as CRP, NPR, and SII.
Optimizing Metabolic and Physical Health in Obese Older Adults: Impact of Exercise Modalities on Insulin Secretion, CNTF, and IGF-1 During Weight Loss
Combining aerobic and resistance exercise with diet-induced weight loss in obese older adults significantly improves insulin secretion, preserves CNTFRα levels, and increases IGF-1, enhancing metabolic and physical function.
Hydroxytyrosol Supplementation Enhances Antioxidant and Anti-Inflammatory Status in Overweight Prediabetic Adults: Insights from a Randomized Controlled Trial
A 16-week randomized trial demonstrates that daily hydroxytyrosol supplementation significantly reduces oxidative stress and inflammatory markers in overweight individuals with prediabetes, highlighting its potential in preventing aging-rel
Tai Chi and Cognitive Enhancement in Older Adults With Type 2 Diabetes Mellitus: Evidence From Randomized Controlled Trials Using Wearable Technology in mHealth Models
Emerging RCT evidence supports Tai Chi’s superior benefits over fitness walking in improving cognitive function and sleep quality among older adults with type 2 diabetes and mild cognitive impairment, facilitated by telemedicine and wearabl
Add-on Probiotics for Inflammatory Depression: Insights from a Double-Blind Randomized Placebo-Controlled Trial
This study evaluated the antidepressant effects of a Lactobacillus probiotic in overweight depressed patients with systemic low-grade inflammation, revealing no overall benefit but highlighting fecal formic acid as a potential biomarker for
Enhancing Vagal Nerve Function with Multi-Species Probiotics: A Promising Therapeutic Avenue for Major Depression
A 3-month RCT demonstrates that multi-species probiotic supplementation improves vagal nerve function, gut microbiome composition, and sleep quality in patients with major depression, suggesting novel gut-brain axis interventions.
Synergistic Effects of Combined Aerobic and Resistance Exercise with Diet on Insulin Secretion and Neurotrophic Factors in Older Adults with Obesity
Combining aerobic and resistance exercise with diet-induced weight loss in older adults with obesity significantly improves insulin secretion, metabolic health, and physical function, likely mediated by ciliary neurotrophic factor receptor
Enhancing Metformin Efficacy and Tolerability in Prediabetes Through a Fermentable Carbohydrate-Rich Diet
A fermentable carbohydrate-enriched diet combined with metformin improves postprandial glycaemia, enhances GLP-1 secretion, and positively alters gut microbiota in prediabetic individuals, offering a personalized nutrition-pharmacology stra
Long-Term Outcomes of the DASH Intervention in Nonobstructive Coronary Artery Disease: Follow-Up of the DISCO-CT Study
A one-year DASH diet intervention led to sustained suppression of proatherogenic chemokine CXCL4 and fewer major cardiovascular events over six years despite reduced adherence and partial loss of initial benefits in nonobstructive CAD patie
Dose-Dependent Enhancement of L-Tryptophan-Induced Gut Hormone Secretion and Appetite Suppression by Intraduodenal Calcium in Obesity
Intraduodenal calcium at doses up to 1000 mg amplifies the anorexigenic effects of L-tryptophan by boosting gut hormones CCK, GLP-1, and PYY, reducing energy intake in obese males, highlighting a novel adjunctive approach for appetite regul
Decoding Metabolic Adaptation: Caloric Restriction’s Impact on Organ Size in the CALERIE 2 Trial
This study explores how caloric restriction influences organ size and metabolic adaptation, using MRI data from the CALERIE 2 trial, revealing nuanced changes in energy expenditure linked to organ-specific tissue loss.
Personalized Anti-Inflammatory Diet Modulates Gut Microbiome and Metabolome to Alleviate Osteoarthritis Pain
A 4-week anti-inflammatory dietary intervention in knee osteoarthritis patients led to targeted shifts in gut microbiota and metabolite profiles associated with significant pain reduction, highlighting the potential of microbiome-informed n
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