408 articles · 20 / page
This randomized clinical trial demonstrates that EHR-based behavioral interventions, such as precommitment and boostering prompts, significantly improve deprescribing rates for potentially inappropriate medications in older adults, providin
Clinical trials reveal that Rifaximin provides faster symptom relief and significantly better adherence than the low FODMAP diet in IBS patients, while also potentially restoring lactase activity in those with small intestinal bacterial ove
A Dutch randomized study reveals that explicitly advising sustainable treatment options can significantly decrease patient trust in high-severity clinical scenarios, highlighting a critical tension between planetary health goals and perceiv
A large-scale analysis of UK dietary data reveals that higher alignment with the EAT-Lancet planetary health diet significantly improves the intake of essential micronutrients like iron, zinc, and calcium, refuting concerns that sustainable
The PACBACK randomized trial reveals that clinician-supported biopsychosocial self-management significantly reduces one-year disability in patients with acute low back pain at high risk of chronicity, whereas spinal manipulation alone offer
A substudy of the global G-CHF registry demonstrates that higher intake of legumes and vegetables significantly reduces the risk of death and hospitalization in heart failure patients, while refined grains increase risk, highlighting the im
A randomized trial demonstrates that a smartphone app-based pulmonary rehabilitation program significantly improves quality of life and physical activity in patients with chronic respiratory diseases, offering a scalable alternative to trad
This review synthesizes recent randomized controlled trials and meta-analyses on calcium supplementation during pregnancy, evaluating its effectiveness in preventing hypertensive disorders such as pre-eclampsia and related maternal and neon
In a world grappling with dual crises—rising chronic disease rates and accelerating climate change—a team…
This review synthesizes data on mifepristone availability at community pharmacies in BC, highlighting geographic coverage, dispensing gaps, and disparities influencing timely access to medication abortion.
This review synthesizes evidence linking adherence to the Planetary Health Diet with reduced risks of myocardial infarction, type 2 diabetes, and improved weight management in women post-gestational diabetes, highlighting BMI’s mediat
A randomized trial of 402 US primary care physicians found that presenting two or more appropriate treatment alternatives (vs one) increased clinicians’ likelihood of changing from a status quo plan to an evidence‑based alternative, especia
Two cohort analyses suggest greater adherence to the EAT‑Lancet diet is linked with lower recurrent non‑fatal vascular events—notably stroke—and that education and sex modify long‑term cardioprotective benefits of this sustainable, plant‑fo
In the CARDIA cohort, higher carbohydrate quality (lower carbohydrate:fibre ratio) and greater intake of fibre-rich foods were associated with more favorable left ventricular structure and function measured 25–30 years after baseline diet a
Multi-objective optimization in the EPIC cohort shows that modest gains in adherence to the EAT‑Lancet diet, increased plant species richness, and substitution of ultra‑processed foods with minimally processed foods can raise nutrient adequ
A concise overview of the newly developed Core Outcome Set for healthy aging in primary care—12 prioritized outcomes to standardize evaluation of health-promotion interventions and improve comparability across studies and programs.
A pragmatic cluster randomized trial found that adding OUD-specific components to collaborative care in primary care clinics reduced days of opioid use more than collaborative care for mental health alone, without clear additional mental he
New research reveals that galactose from dietary sources like milk reprograms liver metabolism, boosting immune T cell activity to combat tumors by preventing their exhaustion.
AEDs improve survival in in-home cardiac arrests with shockable rhythms but are not cost-effective for widespread private home use at current prices and incidence rates, per a large US cohort study using CARES data.
This review synthesizes evidence from the RETREAT RCT and past systematic reviews, highlighting that an unsupervised online Tai Chi program significantly improves knee pain and function in knee osteoarthritis, providing a scalable, accessib
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