Family Medicine & Nutrition
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Planetary Health Diet and Cardiometabolic Risk Reduction in Women with Gestational Diabetes: An Evidence-Based Review
This review synthesizes evidence linking adherence to the Planetary Health Diet with reduced risks of myocardial infarction, type 2 diabetes, and improved weight management in women post-gestational diabetes, highlighting BMI’s mediating ro
Offering Multiple Appropriate Alternatives Increases Primary Care Physicians’ Adoption of Recommended Care: A Randomized Trial
A randomized trial of 402 US primary care physicians found that presenting two or more appropriate treatment alternatives (vs one) increased clinicians’ likelihood of changing from a status quo plan to an evidence‑based alternative, especia
EAT‑Lancet Diet and Recurrent Cardiovascular Events: Lower Stroke Risk and a Signal for Myocardial Infarction in Patients with Established CVD
Two cohort analyses suggest greater adherence to the EAT‑Lancet diet is linked with lower recurrent non‑fatal vascular events—notably stroke—and that education and sex modify long‑term cardioprotective benefits of this sustainable, plant‑fo
Higher-Quality Carbohydrates and Fibre-Rich Foods Associate with Better Left Ventricular Structure and Function: Insights from CARDIA
In the CARDIA cohort, higher carbohydrate quality (lower carbohydrate:fibre ratio) and greater intake of fibre-rich foods were associated with more favorable left ventricular structure and function measured 25–30 years after baseline diet a
Combining Food Biodiversity, Less Processing, and the EAT‑Lancet Diet Improves Nutrient Adequacy and Lowers Environmental Impact: Insights from 368,733 EPIC Participants
Multi-objective optimization in the EPIC cohort shows that modest gains in adherence to the EAT‑Lancet diet, increased plant species richness, and substitution of ultra‑processed foods with minimally processed foods can raise nutrient adequ
A Standard Set for Healthy Aging in Primary Care: Key Recommendations from the New Core Outcome Set (COS) Consensus
A concise overview of the newly developed Core Outcome Set for healthy aging in primary care—12 prioritized outcomes to standardize evaluation of health-promotion interventions and improve comparability across studies and programs.
Collaborative Care for OUD in Primary Care Reduces Opioid Use: Cluster RCT Shows Added Benefit from an OUD-Focused Model
A pragmatic cluster randomized trial found that adding OUD-specific components to collaborative care in primary care clinics reduced days of opioid use more than collaborative care for mental health alone, without clear additional mental he
How Milk Sugar Fuels Immune Cells to Fight Cancer: The Surprising Role of Galactose
New research reveals that galactose from dietary sources like milk reprograms liver metabolism, boosting immune T cell activity to combat tumors by preventing their exhaustion.
Evaluating the Impact and Economics of Home Automated External Defibrillators: Insights from the CARES Registry
AEDs improve survival in in-home cardiac arrests with shockable rhythms but are not cost-effective for widespread private home use at current prices and incidence rates, per a large US cohort study using CARES data.
Online Unsupervised Tai Chi Intervention for Knee Osteoarthritis: Insights from the RETREAT Randomized Clinical Trial and Systematic Reviews
This review synthesizes evidence from the RETREAT RCT and past systematic reviews, highlighting that an unsupervised online Tai Chi program significantly improves knee pain and function in knee osteoarthritis, providing a scalable, accessib
Long-Term Outcomes of Oral Implant Rehabilitation in Patients with Disabilities Under General Anesthesia: A 14-Year Cohort Study
This study evaluates the safety, effectiveness, and longevity of implant-supported prostheses in disabled patients treated under general anesthesia over 14 years.
Basophil Activation Test: A Superior Predictor for Allergic Reactions to Baked and Fresh Cow’s Milk in Children
The Basophil Activation Test offers the highest accuracy in predicting allergic reactions to baked and fresh cow’s milk during oral food challenges, reducing the need for riskier diagnostic tests in children with milk allergy.
Optimizing Food Insecurity Interventions to Lower Blood Pressure: Insights from the Healthy Food First Trial
A factorial RCT in food-insecure adults with hypertension found that healthy food subsidies modestly reduced blood pressure compared with delivered food boxes, while lifestyle counseling and longer duration showed no added benefit.
Dietary Patterns and Intracranial Atherosclerosis Risk in Elderly Patients With Hypertension or Myocardial Infarction: An Evidence-Based Review
Healthy dietary patterns may reduce intracranial atherosclerosis severity in older adults with hypertension or prior myocardial infarction, suggesting diet’s conditional protective role in vascular brain disease.
APOE ε4 Allele: A Key Driver of Cognitive Decline and Neurodegeneration in Older Adults from the Democratic Republic of the Congo
This study reveals that the APOE ε4 allele is linked to increased dementia prevalence, cognitive deficits, brain atrophy, and plasma biomarkers of neurodegeneration in older adults in the DRC, emphasizing its critical role in African popula
Lifetime Walking Intensity and Duration Reduce Amyloid-β Accumulation in Alzheimer’s Disease: Insights from a Korean Longitudinal Cohort
A 4-year longitudinal study reveals that long-duration, high-intensity lifetime walking is associated with reduced amyloid-β accumulation in older adults, suggesting a neuroprotective effect when initiated early in life.
Evaluating Combined Mind-Body Exercise, Cognitive Training, and Nurse-Led Risk Factor Modification in Mild Cognitive Impairment: Insights from a Three-Arm Randomized Controlled Trial
A large RCT in primary care showed no significant cognitive benefits of a combined intervention integrating mind-body physical exercise, cognitive training, and nurse-led risk factor modification over nurse-led risk factor modification alon
Dietary Patterns and Dementia Risk: Insights from a Large UK Biobank Cohort Study
Higher adherence to Mediterranean, MIND, and Recommended Food Score diets is linked to reduced risk of all-cause dementia and Alzheimer disease, highlighting diet as a modifiable factor in dementia prevention.
Planetary Health and Plant-Based Diets: Reducing Type 2 Diabetes Risk in UK Adults
Higher adherence to the Planetary Health Diet Index, reflecting environmentally sustainable plant-based eating patterns, is strongly associated with reduced type 2 diabetes risk in UK Biobank participants, comparable or superior to other es
Comparative Effectiveness of PTSD Treatments in Primary Care: Insights from a Pragmatic Randomized Trial
A pragmatic trial comparing SSRIs and written exposure therapy in primary care PTSD treatment found similar effectiveness initially; switching to SNRI was superior to WET augmentation for SSRI nonresponders.
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