Section
A large multi-site cohort found delirium in 16% of older ED patients, including many discharged home, and linked it to higher admission and 30-day readmission, underscoring the need for standardized screening and supportive care.
A Japanese multicenter registry study suggests ECPR may improve 1-month survival and neurologic outcomes in selected children with out-of-hospital cardiac arrest, although estimates were imprecise and residual confounding remains a major li
In selected children with out-of-hospital cardiac arrest, extracorporeal CPR was associated with higher one-month survival and better neurologic outcomes than continued conventional CPR, though the study was observational and estimates were
A clinical care guideline improved emergency use of nebulized tranexamic acid for post-tonsillectomy bleeding and was associated with fewer returns to the operating room.
A quality-improvement clinical care guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage achieved high protocol adherence and was associated with a marked reduction in operative intervention.
A clinical care guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage was rapidly adopted in the Emergency Department and was associated with fewer returns to the operating room.
A structured emergency department guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage achieved rapid protocol uptake and was associated with a marked reduction in operative hemorrhage control.
A hospital clinical care guideline enabled rapid uptake of nebulized tranexamic acid for eligible post-tonsillectomy hemorrhage and was associated with a marked reduction in operative control of bleeding.
A quality-improvement guideline standardizing nebulized tranexamic acid for post-tonsillectomy hemorrhage achieved high protocol adherence and was associated with a marked reduction in operative hemorrhage control.
In a randomized controlled trial, the STIckER smartphone-based decision aid increased gonorrhea/chlamydia and pharyngeal STI testing in emergency department patients aged 14 to 24 years, while improving decisional clarity, satisfaction, and
A multicomponent emergency department workflow using screening, electronic prompts, and discharge decision support significantly increased naltrexone prescribing for patients with alcohol-related diagnoses.
Intravenous magnesium sulfate added to paracetamol increased early headache-treatment success in the emergency department, but the pain relief was modest and below usual clinical importance thresholds. It also reduced rescue analgesia needs
A large U.S. study found major geographic and socioeconomic differences in how critically injured patients are transported to verified trauma centers, with outcomes varying by region, rurality, and neighborhood deprivation.
A multicenter emergency department study found that CPES performed similarly to sPESI and ESC for short-term PE outcomes, but it better predicted the need for advanced intervention.
The DISTAL trial found no 12-month disability or survival benefit from adding endovascular treatment to best medical therapy in mild-to-moderate medium or distal vessel occlusion stroke.
In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between g
In suspected myocardial infarction, hs-cTnT-gen6 showed diagnostic accuracy comparable to gen5, produced fewer myocardial injury classifications, and supported highly sensitive ESC 0/1-hour and 0/2-hour rule-out and rule-in pathways using a
In EXECT-CPR, transesophageal echocardiography-guided adjustment of compression site during emergency department CPR did not significantly improve ROSC or survival, despite signals of improved hemodynamics and no excess safety concerns.
A large multinational RES-Q registry analysis suggests that the benefit of bridging thrombolysis before thrombectomy is greatest when treatment starts very early, with attenuation after 150 minutes.
In a real-world academic emergency department, ambient AI scribe use was uncommon and concentrated among a small group of physicians, but when used it was associated with shorter documentation and total EHR time.
