Emergency Medicine
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Timely Opioid Administration in Pediatric Emergency Departments Reduces Hospitalizations for Acute Sickle Cell Pain
Prompt opioid delivery in pediatric EDs for sickle cell pain significantly lowers hospitalization rates, with the greatest benefit seen when the first dose is given within 60 minutes and the second dose within 30 minutes.
Reassessing the Safety of Peripheral Vasopressor Use in Early Sepsis: Evidence from a Large Prospective Cohort Study
This study evaluates factors influencing vasopressor route choice in sepsis and demonstrates low complication rates associated with peripheral administration, supporting its safety in early resuscitation.
Optimizing Gonorrhea and Chlamydia Screening for Adolescents in Emergency Departments: Evidence from Targeted and Universal Strategies
Comparative effectiveness evidence from multicenter pediatric emergency departments demonstrates that targeted and universally offered gonorrhea and chlamydia screening increase detection rates versus usual care, highlighting the need for i
Declining Antiviral Prescribing for High-Risk Children with Influenza in US Pediatric Emergency Departments During the COVID-19 Era
Antiviral prescriptions for children at high risk of severe influenza in US pediatric emergency departments decreased by over 50% during the COVID-19 pandemic compared with prepandemic rates, despite unchanged treatment guidelines.
Comprehensive Management of Animal Bites: Integrating Plastic Surgery and Predictive Algorithm Approaches
This article reviews injury profiles from animal bites, emphasizing plastic surgery roles, treatment strategies, and a predictive model for complications, based on a large clinical dataset from Balıkesir University.
Evaluating Fentanyl Use in Pediatric Ileocolic Intussusception Reduction: Implications for Pain Management and Success Rates
A large multicenter study finds no association between fentanyl administration and failed reduction of pediatric ileocolic intussusception, supporting its safe use for analgesia during the painful reduction procedure.
Evaluating Telestroke’s Impact on Acute Ischemic Stroke Treatment Timeliness and Outcomes
Telestroke evaluation increases thrombolysis rates but is associated with longer treatment times and delays in patient transfers in acute ischemic stroke, highlighting the need to address modifiable treatment delays.
Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours
This study developed and validated machine learning models with high accuracy to predict early pediatric sepsis and septic shock within 48 hours using multisite electronic health record data in emergency departments.
Empowering Older Adults in Acute Care: Insights on Shared Decision Making for Treatment Escalation Planning
This qualitative UK study explores older patients’ perspectives on shared decision making for treatment escalation during acute hospital deterioration, highlighting the need for patient autonomy, education, and adaptable clinical approaches
Innovative Respiratory Gas Delivery Device Significantly Extends Survival Time in Simulated Critical Avalanche Burial
A randomized clinical trial demonstrates that a novel avalanche safety device delaying hypoxia and hypercapnia can extend survival time beyond the critical 35-minute asphyxiation window during avalanche burial.
Which Mental-Health Steps Should Trauma Teams Prioritize? A Practical Synthesis of New Guideline Recommendations
A systematic synthesis of clinical practice guideline recommendations for preventing and managing mental disorders after traumatic injury, with prioritized, implementable actions for acute and early recovery care.
Delays in Pediatric Cannabis Toxicology Testing Lead to Increased Neuroimaging in Emergency Departments
Delayed cannabis test results in children under 6 with poisoning symptoms prolong ED visits and influence neuroimaging use. Faster toxicology screening could optimize care and reduce unnecessary scans.
Exertional Heat Stroke: Critical Insights for Emergency Physicians
Exertional heat stroke (EHS) is a life-threatening condition characterized by hyperthermia and CNS dysfunction, necessitating rapid recognition and intervention to prevent multi-organ failure and death. This article reviews its pathophysiol
Enhancing Communication in Trauma ICUs with the Best Case/Worst Case Tool: A Feasible Approach to Improve Prognostic Discussions
The Best Case/Worst Case-ICU communication tool supports trauma ICU teams in effectively discussing prognoses with families, improving decision-making and reducing distress, though implementation faces practical barriers.
Urgent Surgery Versus Fibrinolytic Therapy in Left-Sided Prosthetic Valve Thrombosis: Insights from a Groundbreaking Randomized Trial
This first randomized trial comparing urgent surgery and fibrinolytic therapy (low-dose t-PA) for symptomatic left-sided prosthetic valve thrombosis finds similar efficacy but higher mortality with surgery and higher residual valve dysfunct
Reevaluating Early Blood Pressure Targets in Acute Spinal Cord Injury: Insights from a Multicenter Randomized Trial
A recent randomized clinical trial comparing augmented to conventional blood pressure targets in acute spinal cord injury found no improvement in 6-month neurological outcomes, challenging current practices and highlighting risks of higher
Optimizing Hepatitis C Screening in Emergency Departments: Insights from the DETECT Hep C Randomized Clinical Trial
The DETECT Hep C trial demonstrates nontargeted HCV screening in emergency departments identifies more new infections than risk-based approaches, though linkage to care remains suboptimal, underscoring the need for innovative treatment mode
Parecoxib and Imrecoxib Sequential Therapy: A Breakthrough in Managing Severe Acute Pancreatitis
This multicentre trial shows sequential use of COX-2 inhibitors parecoxib and imrecoxib significantly reduces severe acute pancreatitis (SAP) incidence, shortens organ failure duration, lowers local complications, and decreases 30-day morta
Tick Bites: The Hidden Danger That Sent an Elderly Patient to ICU and How to Protect Yourself
A tick bite led to a severe illness requiring ICU care. Learn about the risks, symptoms, and crucial prevention measures to stay safe from tick-borne diseases.
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