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A multicenter emergency department study found that CPES performed similarly to sPESI and ESC for short-term PE outcomes, but it better predicted the need for advanced intervention.
The DISTAL trial found no 12-month disability or survival benefit from adding endovascular treatment to best medical therapy in mild-to-moderate medium or distal vessel occlusion stroke.
In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between g
In suspected myocardial infarction, hs-cTnT-gen6 showed diagnostic accuracy comparable to gen5, produced fewer myocardial injury classifications, and supported highly sensitive ESC 0/1-hour and 0/2-hour rule-out and rule-in pathways using a
In EXECT-CPR, transesophageal echocardiography-guided adjustment of compression site during emergency department CPR did not significantly improve ROSC or survival, despite signals of improved hemodynamics and no excess safety concerns.
A large multinational RES-Q registry analysis suggests that the benefit of bridging thrombolysis before thrombectomy is greatest when treatment starts very early, with attenuation after 150 minutes.
In a real-world academic emergency department, ambient AI scribe use was uncommon and concentrated among a small group of physicians, but when used it was associated with shorter documentation and total EHR time.
Secondary analysis of TEMPO-2 trial data reveals intracranial hemorrhage in minor stroke patients increases 90-day mortality risk threefold, with higher hemorrhage rates in tenecteplase-treated patients despite most bleeds being non-symptom
A retrospective cohort study reveals that stroke-related disability or mortality after ED discharge for dizziness is rare (0.04% incidence), with most lesions occurring in the anterior fossa. Findings underscore the need for targeted risk s
A novel sixth-gen hs-cTnT assay with a 13 ng/L threshold safely identified twice as many low-risk MI patients at ED presentation vs fifth-gen assays, achieving >99.5% NPV in multinational validation.
The LEGEND trial demonstrates that a high-sensitivity troponin-based rule-out strategy significantly reduces hospital length of stay and cardiac testing while safely excluding acute myocardial infarction in emergency department patients.
A study finds that increased annual trauma patient volume per EMS clinician is associated with significantly reduced 6-hour and in-hospital mortality rates, highlighting the importance of experience in prehospital trauma care.
A multicenter study shows that observation with deferred CT decision-making significantly reduces CT use in children with blunt abdominal trauma, particularly in cases with intermediate clinician suspicion, without increasing missed injurie
A novel matching approach using 911 call time and patient characteristics can effectively identify duplicate EMS responses, enabling more accurate patient-level inferences from response-based datasets with 100% sensitivity and up to 98.6% s
This review synthesizes evidence on sex differences in syncope management, highlighting that while men face higher admission rates and adverse events, these disparities are largely driven by baseline clinical risk factors rather than gender
This study analyzes emergency department visit patterns among suicide decedents, identifying frequent users and a critical 30-day window for intervention after discharge.
A large-scale retrospective study involving over 170,000 patients demonstrates that prolonged emergency department boarding significantly increases the odds of early clinical deterioration and 28-day mortality, emphasizing the urgent need f
Expert consensus highlights a shift in shock treatment, emphasizing that standardized protocols must give way to personalized, physiology-driven bedside care to prevent iatrogenic injury and improve survival.
This evidence-based review analyzes the adoption and clinical outcomes of telemedicine for post-ED follow-up, highlighting that while utilization is currently low (2.8%), it offers a safe alternative to in-person care without increasing ret
This study examines the timing and frequency of emergency department visits among individuals who died by suicide. Research identifies frequent ED use as a high-risk indicator and suggests that the 30-day window following an emergency visit
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