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Prioritized lung transplant recipients exhibit higher severe PGD rates and mortality, yet prioritization itself is not an independent PGD predictor; pre-transplant ECMO is the primary risk factor.
New evidence suggests lower urine output thresholds than current standards better predict acute kidney injury, chronic kidney disease, and mortality in critically ill patients, urging redefinition of oliguria parameters in AKI diagnostics.
This review synthesizes current evidence on high-frequency chest wall oscillation (HFCWO) for airway clearance in acute respiratory failure with bronchial hypersecretion, highlighting recent RCT findings, mechanistic insights, and future re
This article explores findings from a multicenter study evaluating the impact of cardiopulmonary resuscitation ventilation rates on survival in pediatric intensive care, identifying age-specific ventilation targets linked to improved outcom
This study confirms the K-Force grip dynamometer as a responsive tool to detect short-term changes in handgrip strength in ICU-acquired weakness patients, supporting its clinical utility in critical care rehabilitation.
Higher cumulative inotropic exposure during VA ECMO support in cardiogenic shock is associated with increased risk of ECMO weaning failure, mortality, arrhythmias, and delayed lactate clearance, highlighting the need for prospective trials
A 34-day-old male infant with serum sodium >200 mmol/L from accidental salt ingestion was successfully treated with peritoneal dialysis, leading to full recovery.
This study reveals how diabetes and ASCVD alter the link between soluble TNF receptor 1 levels and 90-day sepsis mortality, informing biomarker-guided risk assessment and understanding of sepsis pathobiology.
A large randomized trial finds no difference in 90-day days alive and out of hospital between early vasopressors with restricted fluids versus higher fluids with delayed vasopressors in septic shock, though pulmonary edema was less frequent
This study validates the Patient Dignity Inventory (PDI) as a reliable tool to assess dignity-related distress over 12 months in acute respiratory failure survivors, supporting dignity-centered interventions to improve long-term psychosocia
Ondansetron, a 5-HT3 antagonist, reduces respiratory drive in ARDS patients on mechanical ventilation by attenuating pulmonary C-fiber mediated stimulation, potentially lessening lung injury and improving oxygenation.
Standardizing care for neonates with transient tachypnea significantly reduced NICU length of stay and medical interventions without compromising safety or breastfeeding rates.
Non-Hispanic Black and Hispanic ICU survivors exhibit higher rates of physical impairment at discharge and increased healthcare utilization within one year, highlighting critical racial and ethnic disparities in post-ICU recovery.
This review synthesizes evidence on how individual patient characteristics modify the comparative effects of cefepime versus piperacillin-tazobactam on acute kidney injury and neurologic outcomes in adults hospitalized with acute infection.
This study identifies higher pharmacist-to-patient ratios and interruptions in comprehensive medication management as key contributors to increased mortality among ICU patients, highlighting the need for optimized pharmacist staffing in cri
This multicenter Chinese registry study reveals a high incidence of in-hospital cardiac arrest with low survival rates and highlights critical gaps in postresuscitation care and systemic factors limiting outcomes.
White blood cell count modifies mortality outcomes in sepsis patients treated with cefepime versus piperacillin-tazobactam, suggesting its potential role in guiding antibiotic selection.
A phase 2 randomized trial shows that TISA-818, an anti-inflammatory montelukast-decapeptide conjugate, is safe and may improve respiratory outcomes in ARDS patients, especially non-intubated individuals, supporting larger trials.
A decade-long analysis reveals a modest decline and delayed timing in withdrawal of life-sustaining treatment among patients with traumatic brain injury, highlighting evolving prognostic attitudes and clinical decision-making.
This review synthesizes national data from Spain (2015-2024) revealing a decline in brain death donation (DBD) offset by growth in controlled donation after circulatory death (cDCD), alongside evolving neurocritical care practices influenci
