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This WISDOM Study analysis found that most women with breast cancer pathogenic variants would not have been flagged for high-risk screening by clinical or polygenic risk models alone, supporting population-based genetic testing.
A U.S. geospatial analysis found major state-level disparities in access to registered hand trauma centers, with 13.3% of the population outside a 6-hour catchment and 7.6% still uncovered at 12 hours.
A 2026 Annals commentary argues that boarding and crowding are enduring emergency department realities and that residency education should shift from avoidance to deliberate preparation for safe, effective practice in constrained systems.
An observational study in a Massachusetts FQHC network found that a telehealth navigator program with remote monitoring was associated with a substantial improvement in blood pressure control among Black adults with hypertension.
A historically grounded review of how physicians, librarians, publishers, and now algorithms have filtered the expanding medical literature, shaping what counts as visible, credible, and clinically actionable knowledge.
A multicenter German study shows pulmonary endoscopy produces substantial waste, much of it in procedure rooms, and suggests reusable gowns, procedural bundling, and recycling as practical ways to lower environmental impact.
A transportability analysis suggests the benefits seen in COAPT would likely persist in real-world U.S. patients with secondary mitral regurgitation if COAPT-style care, including optimized medical therapy, were delivered.
A large US claims-based cohort suggests that most open-angle glaucoma suspects have modest annual conversion risk after the first year, and that age- and treatment-informed surveillance intervals may help tailor follow-up intensity.
A multicenter prospective cohort study suggests that substantial surgeon social jet lag, but not midsleep variability alone, is associated with higher 30-day major adverse event risk after surgery and correlates with surgeon burnout.
In a large prospective U.S. cohort, severe maternal morbidity did not reduce breastfeeding initiation, but it was associated with lower odds of breastfeeding beyond 6 months and of exclusive breastfeeding.
A national U.S. study found that patients with epilepsy from rural counties had worse hospital outcomes, including higher mortality, more status epilepticus, longer stays, and less EEG use, highlighting access-related disparities.
A large French cohort study found that higher exposure to several food coloring additives was associated with increased incidence of type 2 diabetes, highlighting the need for further research and possible reevaluation of some additives.
In a nationwide Medicare cohort, chronic wildfire smoke PM2.5 exposure was associated with a modest but significant increase in incident stroke, with stronger effects over longer exposure windows.
A large multicenter study found that emergency department triage mismatches were linked to small delays in care and longer stays, especially for overtriaged patients. Better use of patient history may improve triage accuracy.
Mailed outreach improved colorectal cancer screening in community health centers, with FIT-DNA outperforming FIT. However, colonoscopy follow-up after abnormal stool tests remained low despite navigation support.
This review synthesizes the American Thoracic Society’s 2026 research statement on the US Air Quality Index, identifying critical knowledge gaps and prioritizing five research domains to enhance its effectiveness for patients with res
A large U.S. study found that a contrast sensitivity score of 1.60 logCS marks the point where older adults are more likely to experience everyday vision disability, even when standard visual acuity may seem acceptable.
In the HUNT Study, higher midlife waist-to-height ratio and BMI predicted higher late-life plasma p-tau217 and biomarker-verified Alzheimer dementia, whereas higher adiposity in late life was associated with lower biomarker levels and lower
A small randomized trial found that blocking IL-6 with tocilizumab showed promising, clinically meaningful trends for inflammation-related, hard-to-treat depression, especially for somatic symptoms, fatigue, anxiety, and quality of life, th
A survey study found three distinct patient preference patterns for anticoagulation after hip or knee replacement: clot-prevention focused, balanced, and cost-focused. These differences may help personalize postoperative blood thinner choic
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