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Clinical Updates

Immunogenicity and Safety of Pentavalent Meningococcal MenABCWY Vaccine in Adolescents and Young Adults: Integrated Evidence from Late-Phase Clinical Trials

This review synthesizes phase 2 and 3 trial data demonstrating that the pentavalent MenABCWY vaccine is immunologically non-inferior and well tolerated compared with MenB-fHbp and MenACWY-CRM vaccines, offering a simplified, effective vacci

Sep 4, 2026Sign in to read
news

Screen Use and Children’s Language Development From Ages 5 to 7 Years

This study examines the relationship between children’s and parents’ screen use and language development in children aged 5 to 7 years, finding parental smartphone use may slow vocabulary growth, while device ownership correlate

Sep 4, 2026
Clinical Updates

Receipt of Pharmacotherapy and Healthcare Utilization Among US Adults with Alcohol or Opioid Use Disorder: Insights from 2022-2023 National Data

Few US adults with alcohol or opioid use disorder reported addiction pharmacotherapy use in 2022-2023. Pharmacotherapy receipt was linked to increased healthcare utilization, underscoring the need for early outpatient intervention strategie

Sep 3, 2026
news

National Health Systems and Their Crucial Role in Reducing Lung Cancer Mortality: Insights from Global Data

This article explores how health system factors like spending, workforce density, and radiotherapy availability influence lung cancer mortality worldwide, highlighting actionable targets for improving outcomes globally.

Aug 31, 2026
news

Medicaid Expansion and Severe Maternal Morbidity: Evaluating the Impact of the Affordable Care Act on Delivery Outcomes

This study analyzes the ACA Medicaid expansion’s effect on severe maternal morbidity during delivery hospitalizations, finding increased Medicaid coverage but no significant change in severe maternal morbidity rates, underscoring the

Aug 31, 2026
General Surgery

Neighborhood Disadvantage and Mortality Risk After Major Hepatectomy: Insights from the Area Deprivation Index

This study links higher neighborhood deprivation with increased 90-day mortality following major hepatectomy, highlighting social determinants as vital preoperative risk factors.

Aug 31, 2026
Cardiology

Sustained Cardiovascular Benefits of Intensive Blood Pressure Management Led by Nonphysician Providers: 7-Year Follow-Up of the CRHCP Trial

Long-term intensive BP control led by trained nonphysician community providers significantly lowers cardiovascular risk over 7 years, with benefits persisting 3 years post-intervention in rural China.

Aug 30, 2026
Cardiology

Impact of a Community- and Family-Based Intervention on Blood Pressure Reduction in Rural China: Insights from a Cluster-Randomized Trial

This cluster-randomized trial in rural China demonstrates that a coordinated community- and family-based intervention effectively lowers systolic blood pressure at the population level, highlighting the importance of sustained community eng

Aug 27, 2026
Diabetes & Endocrinology

Financial Toxicity and Cost-Related Nonadherence: Challenges in Adult Type 1 Diabetes Management

Adults with type 1 diabetes face substantial financial toxicity and cost-related nonadherence, especially younger adults, underscoring the need for targeted interventions beyond traditional social determinants of health.

Aug 27, 2026
Internal Medicine

Evaluating the Impact of the MISSION Act on VA Specialty Care Referrals and Wait Times: A National Cohort Study

Following the 2018 MISSION Act expansion, VA specialty referrals and community care outsourcing increased substantially without reducing outpatient specialty wait times, signaling the need for alternative access-improvement strategies.

Aug 27, 2026
Clinical Updates

Technology-Guided Diet Counseling Training Enhances Resident Physicians’ Shared Decision-Making Skills in Primary Care

Technology-guided diet counseling training using the Nutri platform improves resident physicians’ attitudes, self-efficacy, and intention to discuss diet, facilitating shared decision making in routine primary care.

Aug 26, 2026Sign in to read
Neurology

Bridging Social Determinants of Health and Multidimensional Frailty Among Older Adults: A Domain-Specific Latent Class and Network Analysis

This study explores how economic, educational, healthcare, neighborhood, and social factors link to multiple frailty dimensions in Chinese older adults, highlighting cognition as a key intermediary.

Aug 25, 2026
Clinical Updates

Informed Consent in International Critical Care Trials: Insights from the REVISE Stress Ulcer Prophylaxis Study

This review examines informed consent patterns and predictors in an international ICU trial on stress ulcer prophylaxis, highlighting the shift to deferred consent, pandemic influences, and implications for critical care research ethics.

Aug 24, 2026
Critical Care

Bridging the Gap: Gender Disparities in Critical Care Authorship Across Economic Contexts

This bibliometric study reveals persistent gender disparities in authorship of critical care publications, with women better represented in low- and middle-income countries and a modest increase in female authorship from 2018 to 2022 global

Aug 24, 2026Sign in to read
Neurology

Lifelong Risk of De Novo Aneurysm Formation in Young Survivors of Aneurysmal Subarachnoid Hemorrhage: A Four-Decade Perspective

Young survivors of aneurysmal subarachnoid hemorrhage face a lifelong risk of developing new aneurysms, with female sex, smoking, and family history as key risk factors. Smoking cessation reduces this risk, supporting need for lifelong surv

Aug 24, 2026Sign in to read
Internal Medicine

Randomized Quality Improvement Trials: Enhancing Healthcare Safety with Ethical Oversight

Randomized Quality Improvement (RQI) trials offer robust evidence for healthcare interventions but raise ethical and regulatory challenges. A proposed framework provides streamlined oversight enabling safer, evidence-based care improvements

Aug 24, 2026Sign in to read
news

Air Pollution and Its Impact on Age at Natural Menopause: Insights from the SWAN Study

High exposure to ambient NO2 and O3 air pollutants is associated with approximately one year earlier natural menopause, highlighting environmental risks to women’s reproductive aging.

Aug 24, 2026Sign in to read
Diabetes & Endocrinology

Racial, Ethnic, and Socioeconomic Disparities in Islet Autoantibody Patterns Among Individuals at Risk for Type 1 Diabetes

Islet autoantibody positivity varies significantly among racial and ethnic groups and is influenced by socioeconomic deprivation, implicating tailored screening and prevention strategies for equitable diabetes care.

Aug 24, 2026
General Surgery

Bridging the Gap: Evaluating Global Surgery Education Among Medical Students in Australia and New Zealand

This study highlights significant gaps in global surgery education among medical students in Australia and New Zealand, revealing limited curricular exposure despite strong student interest and support for inclusion in medical training.

Aug 23, 2026
General Surgery

Impact of Trauma on Social Risk: Insights from Serial Hospital Data Screening

This study reveals that trauma significantly increases social risks such as food insecurity and housing instability, especially in younger adults, highlighting the need for targeted interventions to mitigate socioeconomic consequences post-

Aug 21, 2026
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