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Telemedicine as a Strategic Tool for Post-Emergency Department Care Transitions: Analysis of Utilization and Safety, 2020–2022
This evidence-based review analyzes the adoption and clinical outcomes of telemedicine for post-ED follow-up, highlighting that while utilization is currently low (2.8%), it offers a safe alternative to in-person care without increasing ret
Post-Pandemic Firearm Acquisition and Household Exposure: Insights from the 2024 National Firearms Survey
The 2024 National Firearms Survey reveals that 29.8 million US adults acquired firearms between 2021 and 2024. This trend introduced 11.2 million new owners, significantly increasing household exposure for millions of adults and children, r
The Persistence of Ophthalmic Scarcity: A 23-Year Longitudinal Analysis of Drug Shortages in the United States
This review analyzes ophthalmic drug shortages from 2001 to 2024, revealing that eye medications face longer shortage durations than other drug classes, significantly influenced by patent status and manufacturing transparency.
Strengthening the Patient Voice: New Guidance for Qualitative Research in Internal Medicine
This article outlines new expert consensus on conducting rigorous qualitative research in internal medicine, providing a roadmap for investigators to move beyond numbers and capture the human experience of healthcare through methods like in
Beyond Aging: Traumatic Brain Injury and Depression Emerge as Leading Predictors of Dementia in US Veterans
A large-scale analysis of the VA Million Veteran Program reveals that TBI, depression, and specific military environmental exposures significantly elevate the 10-year risk of Alzheimer’s and related dementias, highlighting critical targets
Severe Obesity Triples Heart Failure Risk: New Insights from the Cross-Cohort Collaboration
A massive study of nearly 290,000 participants reveals that severe obesity (BMI ≥40) triples the risk of heart failure and nearly triples the risk of atrial fibrillation, with significant sex-based differences in stroke and mortality risk.
MUTTON-HF: Can Reclaiming Indigenous Food Systems Reduce Heart Failure Readmissions?
The MUTTON-HF trial evaluates whether culturally and medically tailored meals, incorporating traditional Diné (Navajo) foods, can improve clinical outcomes and quality of life for Indigenous heart failure patients facing nutrition insecurit
High Effectiveness and Rare Safety Risks: Real-World Meta-Analysis Validates RSV Vaccination for Older Adults
A comprehensive meta-analysis of 121.8 million individuals confirms that RSV vaccines are approximately 75% effective against hospitalization and severe disease in older adults, despite low global uptake and a rare risk of Guillain-Barré sy
Cardiovascular Risk Scores Overestimate Mortality in Mexican Adults: The Urgent Need for Population-Specific Recalibration
A prospective study of over 112,000 adults in Mexico City reveals that standard CVD risk scores consistently overestimate 10-year fatal risk. Recalibration of the Globorisk-fatal model significantly improves predictive accuracy, highlightin
Long-term Immunological and Clinical Outcomes of Monkeypox Virus Infection versus MVA-BN Vaccination: A 24-Month Longitudinal Cohort Analysis
This 24-month Belgian cohort study demonstrates that natural MPXV infection induces more durable and robust immunity than MVA-BN vaccination. While clinical symptoms mostly resolve within a year, persistent scarring remains common, and vacc
Scaling Tobacco Cessation in HIV Care: National Quitlines as an Effective Alternative to Resource-Intensive Interventions
A landmark pragmatic randomized controlled trial in Vietnam reveals that proactive Quitline referrals are as effective as nurse-led counseling and nicotine replacement therapy for smoking cessation among people living with HIV, offering a s
Healing the Heart with Tradition: The Promise of the MUTTON-HF Program in the Navajo Nation
A groundbreaking clinical trial demonstrates that medically tailored meals featuring traditional Indigenous foods can significantly improve heart failure outcomes and food security in rural Navajo communities.
Beyond Exercise Alone: The Synergistic Power of Combined High-Intensity Circuit Training and Sleep Health Interventions
This randomized clinical trial demonstrates that combining high-intensity circuit training with targeted sleep health interventions significantly improves objective sleep quality and cardiometabolic markers in young women, outperforming eit
Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes
A randomized clinical trial demonstrates that combining high-intensity circuit training (HICT) with sleep health (SH) counseling significantly outperforms mono-interventions in improving sleep efficiency, reducing wakefulness, and enhancing
China’s Workforce Faces Alarming Cancer Risk Profiles: New Baseline Data from the WECAN Project
A cross-sectional analysis of 841 workers across China reveals a high prevalence of modifiable cancer risk factors, including poor diet, smoking, and low screening rates. The study highlights significant regional disparities, calling for ta
Strategic Release of Wolbachia-Infected Mosquitoes Reduces Dengue Risk by Over 70% in Urban Singapore
A large-scale cluster-randomized trial in Singapore demonstrates that releasing male Aedes aegypti mosquitoes infected with the wAlbB Wolbachia strain significantly suppresses wild-type populations and reduces the incidence of symptomatic d
Spirituality as a Protective Factor Against Substance Use Disorders: Evidence from a 21st-Century Meta-Analysis
A comprehensive meta-analysis of longitudinal studies involving over 540,000 participants reveals that spirituality and religious involvement are associated with a 13-18% reduction in harmful alcohol and drug use, offering significant impli
Is the Planetary Health Diet Nutritious Enough? New Evidence from a Swedish Population Study
A large-scale Swedish study evaluates the nutritional adequacy of the EAT-Lancet diet. Findings suggest it provides sufficient micronutrients for most, though women may face an increased risk of anemia, highlighting the need for careful die
Substantial HIV Burden and Critical Gaps in the Care Cascade Among Men Who Have Sex With Men in Iran
A nationwide biobehavioural survey in Iran reveals a 4.2% HIV prevalence among MSM, highlighting significant disparities in viral suppression despite moderate linkage to care, emphasizing the need for targeted, stigma-free interventions.
Standard Preventive Interventions for Vasovagal Reactions Fail to Show Benefit in Massive 1.4 Million Donor Trial
The STRIDES trial, the largest of its kind, demonstrates that isotonic drinks, extended rest, modified muscle tension, and psychosocial support do not significantly reduce vasovagal reactions in blood donors compared to existing UK standard
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