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A large Dutch cohort study reveals fatigue and cognitive impairment as predominant symptoms in females with prolactinoma, with active disease linked to higher psychological burden despite dopamine agonist treatment.
This review synthesizes a meta-analysis of relapse trajectories following paliperidone discontinuation with evidence on antipsychotic maintenance and discontinuation strategies, highlighting individualized risk stratification and clinical i
This qualitative study reveals how spiritual distress shapes patients’ fears and hopes before elective surgery, emphasizing the need for routine spiritual well-being assessment to support resilience and improve perioperative care.
This study explores how self-reported mood-related symptoms influence early discontinuation of hormonal and nonhormonal contraceptives, revealing complex interactions between baseline mood, contraceptive type, and discontinuation behavior.
This review synthesizes evidence from a pivotal randomized clinical trial and complementary literature on psychotherapeutic interventions addressing the psychological impact of killing in war, emphasizing improvements in PTSD, moral injury,
This qualitative study explores how couples jointly cope with endometriosis, revealing shared challenges and adaptive strategies that bolster relational resilience and psychological wellbeing.
This study reveals that psychological stress, anxiety, PTSD, and military sexual trauma are linked to increased urinary incontinence severity and affect response to behavioral treatments among women veterans, underscoring the importance of
This article reviews the complex interplay between major depressive disorder during pregnancy and selective serotonin reuptake inhibitor treatment, highlighting the importance of prioritizing maternal mental health to optimize outcomes for
This study investigates how real-life versus social-media-based emotional support relates to loneliness among US adults, revealing stronger links between real-life support and reduced loneliness.
This review synthesizes evidence linking smartphone acquisition and use at age 13 to depression, obesity, and sleep insufficiency at age 14, highlighting that use intensity rather than mere acquisition mediates health risks, with behavioral
This review synthesizes evidence highlighting the high prevalence and interrelation of sleep disturbances, mood symptoms, and cognitive impairments in chronic mild traumatic brain injury (mTBI), emphasizing the need for integrated assessmen
This study investigates the genetic risk structure of 18 psychiatric and substance use disorders using high-quality Swedish registries, identifying six distinct genetic factors and highlighting shared and unique genetic influences among dis
Nearly half of psychoactive medications newly prescribed after ICU stays in American adults lack documented diagnostic justification, persisting for up to two years post-hospitalization.
An international study reveals that childhood trauma’s association with bipolar disorder is partially mediated by brain morphology changes, particularly in hippocampal volume and frontal cortical thickness.
A large-scale study identifies key active components of psychosocial interventions delivered by non-specialists, revealing social support, behavioral activation, and problem management as most effective for treating common mental disorders,
This article critically examines the FDA’s approval of gepirone ER for major depressive disorder despite multiple negative trials, highlighting regulatory flexibility, statistical and clinical considerations, and implications for tran
This Swedish register-based study reveals that GLP-1 receptor agonists are associated with significantly reduced hospitalisations for alcohol and substance use disorders during treatment, with some lasting benefits after discontinuation of
This randomized trial compared connectivity-based versus scalp-based targeting of accelerated TMS in treatment-resistant depression, showing greater antidepressant effects with individualized connectivity-guided targeting.
In Eileen Chang's classic novel Red Rose, White Rose , she mocked men who are fickle in love: "Maybe every man has had two such women—at least two. Ma
A reader, Mark, asked: "Hey Nineteen, my wife and I have been married for two years. We have a great relationship, but we keep running into one issue:
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