Diabetes & Endocrinology
Latest news
609 articles · 20 / page
Impact of Multifactorial Interventions on Retinopathy in Type 2 Diabetes: Insights from the J-DOIT3 Trial
This analysis highlights how intensive multifactorial management and glycemic control influence diabetic retinopathy onset, emphasizing the risks associated with hypoglycemia despite good glycemic control.
Closed-Loop Insulin Delivery in Type 1 Diabetes During Pregnancy: Insights from the CIRCUIT Randomized Clinical Trial and Contemporary Evidence
The CIRCUIT trial demonstrates that closed-loop insulin delivery significantly improves glycemic control during pregnancy in type 1 diabetes, increasing time in pregnancy-specific glucose range and reducing hypoglycemia risks relative to st
Navigating the Frontiers of Premature Ovarian Insufficiency Research: Insights from the Top 100 Influential Articles
A comprehensive bibliometric analysis of the 100 most-cited articles in premature ovarian insufficiency reveals key research trends, leading contributors, and emerging scientific directions in genetics, cardiovascular disease, and immunolog
Nucleoside Reverse Transcriptase Inhibitors: A Novel Therapeutic Avenue Against Inflammaging and Age-Related Diseases
NRTIs, traditionally used in HIV and HBV treatment, demonstrate promising anti-inflammatory effects that may reduce the incidence of age-related diseases by inhibiting inflammaging processes associated with endogenous retroelements.
Semaglutide for Metabolic Health in Schizophrenia: Insights from the HISTORI RCT
The HISTORI trial demonstrates that semaglutide significantly improves glycemic control, reduces weight, and enhances physical quality of life in schizophrenia patients treated with second-generation antipsychotics, without worsening psychi
Leveraging the Planetary Health Diet to Reduce Type 2 Diabetes Risk and Environmental Impact: Insights from the EPIC-Norfolk Study
Higher adherence to the planetary health diet is linked with a 32% reduced risk of type 2 diabetes and significantly lower greenhouse gas emissions, supporting its role in preventing diabetes and promoting sustainability.
Planetary Health and Plant-Based Diets: Reducing Type 2 Diabetes Risk in UK Adults
Higher adherence to the Planetary Health Diet Index, reflecting environmentally sustainable plant-based eating patterns, is strongly associated with reduced type 2 diabetes risk in UK Biobank participants, comparable or superior to other es
Impact of Diabetes on the Triglyceride-Glucose Index and Cardiovascular Outcomes in Coronary Heart Disease: A Comprehensive Meta-Analysis
This meta-analysis of 36 cohort studies shows that higher triglyceride-glucose index levels predict increased risk of major adverse cardiovascular events in coronary heart disease patients, with differential effects observed by diabetes sta
Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study
This study demonstrates that the triglyceride glucose-waist height ratio (TyG-WHtR) index independently predicts cardiometabolic multimorbidity risk in Chinese adults aged ≥45, showing a linear dose-response relationship and improved predic
Joint Impact of TyG-Related Indices and eGDR on Cardiometabolic Multimorbidity Risk in Chinese Adults: Insights from a Nationwide Cohort
This study elucidates that high triglyceride glucose (TyG) related indices combined with low estimated glucose disposal rate (eGDR) synergistically elevate cardiometabolic multimorbidity (CMM) risk in middle-aged and older Chinese adults, e
Insulin Resistance Indices as Predictors of Cardio-Renal-Metabolic Multimorbidity: Insights from the UK Biobank
This study demonstrates that insulin resistance indices, particularly TyG-WC, TyG-WHtR, and METS-IR, robustly predict the risk and progression of cardio-renal-metabolic multimorbidity, with inflammation and kidney function mediating these a
Impact of Dietary Patterns on the Progression of Chronic Kidney Disease in Cardio-Metabolic Disorders: Insights from Multi-State Models in a Large UK Cohort
This study reveals that adherence to the American Heart Association diet significantly reduces CKD progression risk from cardio-metabolic disorders, underscoring its role in early intervention strategies.
Revisiting Obesity Classification: Insights from a Population-Based Survey in Peru Using New Clinical Frameworks
This review examines a landmark Peruvian study applying new obesity definitions that incorporate clinical dysfunction and adiposity measures beyond BMI, revealing substantial underdiagnosis with traditional approaches and ethnic variation i
Long-Term Comparative Outcomes of Gastric Bypass and Sleeve Gastrectomy in Type 2 Diabetes: Evidence from a Swedish Matched Cohort Study
A Swedish nationwide study reveals Roux-en-Y gastric bypass yields superior long-term benefits in type 2 diabetes remission and reduced mortality compared to sleeve gastrectomy, despite higher risks of nutritional deficiencies and psychiatr
Bridging the Gaps in Global Diabetes Care: Insights from Two Decades of the Global Burden of Disease Study
A comprehensive analysis reveals ongoing challenges in diabetes diagnosis, treatment, and glycaemic control worldwide, highlighting the urgent need for enhanced care strategies, especially in low- and middle-income regions.
Enhanced Weight Reduction with Once-Weekly Semaglutide 7.2 mg in Obesity Management: Insights from the STEP UP Phase 3b Trial
The STEP UP trial demonstrates that once-weekly semaglutide 7.2 mg significantly improves weight loss outcomes versus 2.4 mg and placebo in adults with obesity, with a manageable safety profile.
Monlunabant Shows Promise for Weight Loss in Obesity and Metabolic Syndrome: A Phase 2A Trial Review
This phase 2a trial demonstrates that monlunabant induces significant weight loss across various doses in obese adults with metabolic syndrome, with dose-dependent adverse events highlighting the need for further safety evaluation.
Enhancing Prognostication in Papillary Thyroid Cancer: Integrating BRAF and TERT Mutations into the AJCC Staging System
Incorporating BRAF and TERT promoter mutations into the AJCC classification for papillary thyroid cancer significantly improves mortality risk prediction, refining patient stratification beyond traditional clinical staging.
IBI311, an IGF-1R Inhibitor, Shows Promising Results for Active Thyroid Eye Disease in Chinese Patients: Insights from the RESTORE-1 Trial
The RESTORE-1 phase 3 trial demonstrates that IBI311 significantly improves proptosis and inflammation in Chinese patients with active thyroid eye disease, with a favorable safety profile.
Obesity Interventions and Male Fertility: Unraveling the Effects of Weight Loss on Reproductive Health
This systematic review and meta-analysis evaluates the effects of obesity interventions—lifestyle modification, pharmacotherapy, and bariatric surgery—on male fertility, highlighting improvements with lifestyle changes and limited benefits
Browse by specialty
Open language-specific specialty feeds and department pages.