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This large cohort study demonstrates that biologic therapy in pregnant women with psoriasis is not associated with increased adverse pregnancy outcomes and may reduce risks of spontaneous abortion and gestational diabetes.
A composite internal stabilization strategy using an internal hemostatic network significantly reduced postoperative hematoma incidence to zero in 356 facelift procedures, compared to 5.9% with conventional methods, enabling safer recovery
An analysis of 27,773 pediatric tracheal intubations reveals 1.2% associated cardiac arrest, highlighting preventable factors such as multiple intubation attempts and benefits linked to video laryngoscopy and specific medications.
Despite substantial potential revenue, only 15% of US primary care clinicians adopted Medicare’s Advanced Primary Care Management codes in 2025, with administrative challenges as key barriers.
A long-term follow-up of the SPRINT trial shows no significant difference in recurrent stroke or mortality rates between initial low and moderate fixed doses of hydroxyurea in sickle cell disease, emphasizing event clustering within the fir
New research proposes clear, patient-anchored criteria for defining chronic cough control, highlighting that fewer patients achieve true cough relief than previously thought, underscoring the need for improved therapies.
Morgagnian cataracts present with severe visual impairment, elevated intraocular pressure, and zonular instability. Surgical management is challenging but can significantly improve vision and reduce pressure with individualized approaches.
A 10-year retrospective study of pediatric parotidectomy reveals primary parotid tumors, predominantly malignant acinic cell carcinoma, as the leading indication, with a low rate of permanent complications but a notable risk of temporary fa
This article reviews the incidence, timing, and risk factors of portomesenteric venous thrombosis (PVT) following pancreatic cancer surgery involving venous resection, highlighting the impact of surgical standardization and neoadjuvant radi
This study evaluates the societal cost-effectiveness of oral antihyperglycemic agents compared to insulin for gestational diabetes treatment, showing oral agents offer comparable benefits at potentially lower costs with small quality-adjust
US emergency departments increasingly discharge transient ischemic attack patients with extensive imaging, reflecting a shift from inpatient to expedited outpatient evaluation, raising questions about cost, feasibility, and rural healthcare
A 12-week metyrapone regimen lowers blood pressure and reduces epicardial fat in patients with mild autonomous cortisol secretion, suggesting cardiovascular improvements without altering cardiac morphology or function.
This review elucidates the contrasting roles of ACADM-mediated fatty acid β-oxidation in atherosclerosis and abdominal aortic aneurysm, highlighting differential lipid metabolism and translational implications for diagnosis and therapy.
This study reveals sustained elevations in inflammatory and cartilage metabolism serum biomarkers during the first year after ACL reconstruction, indicating ongoing joint biological responses beyond surgery and rehabilitation.
The RCBI trial demonstrates that targeted interventions beginning prior to release and continuing postrelease significantly reduce recidivism and improve coping and executive function in incarcerated men with traumatic brain injury.
The phase 3 SAFFRON trial demonstrated that osimertinib combined with savolitinib significantly improves progression-free and overall survival versus platinum-pemetrexed chemotherapy in advanced EGFR-mutated NSCLC harboring MET overexpressi
Saroglitazar, a dual PPAR α/γ agonist, demonstrated significant biochemical improvement and ALP normalization in primary biliary cholangitis patients refractory or intolerant to UDCA, with favorable safety over 52 weeks in a phase 2b/3 tria
Arthroscopic Bankart repair in young patients with minimal glenoid bone loss shows high clinical improvement and return to sport but a considerable recurrence rate, especially among contact sport athletes, highlighting the need for careful
The LAST-long trial investigated a community-based, individualized stroke intervention and found that age—but not frailty—significantly modifies its effectiveness, with older stroke survivors (≥80 years) experiencing less favorable outcomes
A large Swedish cohort study reveals that dental diseases and tooth loss are associated with increased risk of primary liver cancer, highlighting the importance of oral health in systemic disease prevention.
