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Stepped Care Plus Cash Incentives Cuts 3‑Year Diabetes Incidence in Multiethnic Asian Prediabetes Cohort
AIprediabetes

Stepped Care Plus Cash Incentives Cuts 3‑Year Diabetes Incidence in Multiethnic Asian Prediabetes Cohort

By MedXY|Nov 17, 2025

The Pre-DICTED randomized trial found a stepped-care diabetes prevention program augmented with financial incentives reduced 3‑year diabetes conversion (34.8% vs 47.3%; adjusted RR 0.74), with metformin added for persistent high-risk partic

Does AI Make Endoscopists Lazy? New Multicentre Data Show Reduced Adenoma Detection After AI Exposure
AIAdenoma Detection Rateartificial intelligence

Does AI Make Endoscopists Lazy? New Multicentre Data Show Reduced Adenoma Detection After AI Exposure

By MedXY|Nov 9, 2025

A multicentre observational study reports a 6% absolute fall in adenoma detection rate for non‑AI colonoscopies after clinicians were exposed to AI-assisted polyp detection—raising concerns about endoscopist deskilling and the need for safe

Wearable Monitoring Shows Sustained Increases in Daily Activity After Total Knee Arthroplasty, with a 6‑Month Recovery Window
AIPhysical Activitypostoperative recovery

Wearable Monitoring Shows Sustained Increases in Daily Activity After Total Knee Arthroplasty, with a 6‑Month Recovery Window

By MedXY|Nov 5, 2025

A prospective cohort using Apple Watch data demonstrated meaningful increases in step count, standing time and gait speed after unilateral total knee arthroplasty, peaking at 6 months and persisting at 12 months.

How Eli Lilly and NVIDIA’s AI Supercomputer is Revolutionizing Drug Discovery
AIartificial intelligenceEli Lilly

How Eli Lilly and NVIDIA’s AI Supercomputer is Revolutionizing Drug Discovery

By MedXY|Nov 4, 2025

Eli Lilly and NVIDIA have partnered to launch the largest AI-powered supercomputing platform in pharma, aiming to accelerate drug discovery, personalize medicine, and enhance manufacturing through unprecedented computational power.

AI-RAPNO: Translating Artificial Intelligence into Reliable Response Assessment for Pediatric Neuro-Oncology
AIAIimaging

AI-RAPNO: Translating Artificial Intelligence into Reliable Response Assessment for Pediatric Neuro-Oncology

By MedXY|Nov 4, 2025

AI-RAPNO synthesizes current AI developments for pediatric brain tumour imaging and provides practical recommendations to improve trustworthiness, generalisability, and clinical implementation of AI-driven response assessment using the RAPN

Digital‑Twin Decision Aid for Knee Osteoarthritis Improves Decision Quality and 6‑Month Function: Randomized Trial Results
AIAIorthopedics

Digital‑Twin Decision Aid for Knee Osteoarthritis Improves Decision Quality and 6‑Month Function: Randomized Trial Results

By MedXY|Nov 1, 2025

An AI-enabled decision aid that generated patient-specific digital twins improved decision quality, reduced decisional conflict and regret, and produced better 6–9 month knee function versus education alone in patients considering total kne

Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program
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Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program

By MedXY|Oct 29, 2025

This review examines the first phase 3 randomized trial demonstrating that an AI-powered Diabetes Prevention Program lifestyle intervention is noninferior to human coaching in improving weight loss, HbA1c, and physical activity among adults

Harnessing Cancer-Testis Antigens for Precision Immunotherapy in Head and Neck Cancer
AIHead and Neck Squamous Cell Carcinomaimmunotherapy

Harnessing Cancer-Testis Antigens for Precision Immunotherapy in Head and Neck Cancer

By MedXY|Oct 24, 2025

This study identifies specific cancer-testis antigens (CTAs) as promising targets for personalized immunotherapy in head and neck squamous cell carcinoma (HNSCC), validated across multiomic datasets to enhance therapeutic precision.

Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial
AIadherenceCoronary heart disease

Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial

By MedXY|Oct 23, 2025

This study evaluates how smartwatch-assisted home-based cardiac rehab improves exercise adherence and health outcomes in coronary heart disease patients.

Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching
AIcoronary artery diseaseremote monitoring

Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching

By MedXY|Oct 23, 2025

This review discusses a landmark study demonstrating how wearable devices and online coaching improve exercise capacity in coronary artery disease patients, highlighting advancements in remote cardiac rehabilitation.

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer
AIartificial intelligenceExtranodal Extension

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer

By MedXY|Oct 22, 2025

An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore

Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours
AIemergency medicinemachine learning

Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours

By MedXY|Oct 21, 2025

This study developed and validated machine learning models with high accuracy to predict early pediatric sepsis and septic shock within 48 hours using multisite electronic health record data in emergency departments.

Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?
AIhealth disparitiesMedicare Advantage

Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?

By MedXY|Oct 21, 2025

This retrospective national cohort study reveals that Medicare Advantage (MA) enrollees undergoing major cancer surgery are less likely to receive care at high-quality hospitals compared to traditional Medicare beneficiaries, raising concer

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology
AIartificial intelligencemelanoma

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology

By MedXY|Oct 21, 2025

This study demonstrates that an AI algorithm provides more reproducible and prognostically relevant assessment of tumor-infiltrating lymphocytes in melanoma compared to traditional pathologist methods, offering a promising tool to improve c

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives
AIartificial intelligenceimmune checkpoint inhibitors

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives

By MedXY|Oct 21, 2025

AI-detected tumor-infiltrating lymphocytes on routine histology independently predict response and survival in advanced melanoma treated with anti-PD-1 therapies, outperforming manual scoring and offering an accessible biomarker for immune

患者向けデジタルヘルス介入による肺がんスクリーニング受診率の向上:ランダム化比較試験からの洞察
AI

患者向けデジタルヘルス介入による肺がんスクリーニング受診率の向上:ランダム化比較試験からの洞察

By MedXY|Oct 21, 2025

デジタルヘルスプログラムは、高リスク個体の肺がんスクリーニング率を大幅に向上させ、予防医療の改善にデジタルツールの潜在力を示しています。

Enhancing Lung Cancer Screening Uptake Through a Direct-to-Patient Digital Health Intervention: Insights from a Randomized Clinical Trial
AIrandomized clinical trial

Enhancing Lung Cancer Screening Uptake Through a Direct-to-Patient Digital Health Intervention: Insights from a Randomized Clinical Trial

By MedXY|Oct 21, 2025

A digital health program significantly increased lung cancer screening rates among high-risk individuals, underscoring digital tools’ potential to improve preventive care.

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit
AIartificial intelligenceEquity

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit

By MedXY|Oct 14, 2025

Artificial intelligence is reshaping health care, offering vast potential benefits alongside significant challenges. The JAMA Summit emphasizes the need for robust evaluation, equitable deployment, and multi-stakeholder collaboration to ens

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis
AIartificial intelligenceSexually Transmitted Infections

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis

By MedXY|Oct 6, 2025

AI demonstrates high accuracy in identifying mpox and other anogenital conditions from clinical images, yet significant research gaps and validation needs remain before clinical adoption.

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications
AI

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications

By MedXY|Oct 6, 2025

A cross-sectional study identifies four distinct profiles of nonverbal learning disability (NVLD) in children, revealing significant heterogeneity in visual-spatial deficits, academic skills, and psychiatric diagnoses, highlighting implicat

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