Nursing & care
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Prompt and Intensive Antiviral Chemoprophylaxis in Nursing Home Influenza Outbreaks: Evidence Synthesis and Clinical Implications
Intensive oseltamivir chemoprophylaxis for ≥70% of nursing home residents within 2 days of influenza outbreak reduces hospitalization risk, underscoring prompt antiviral intervention as a critical outbreak control strategy.

Early, Broad Oseltamivir Prophylaxis May Cut Hospitalizations in Nursing Home Influenza Outbreaks
Prompt oseltamivir prophylaxis covering at least 70% of eligible nursing home residents within 2 days of outbreak detection was associated with fewer hospitalizations, but not lower mortality.

Fast, Broad Oseltamivir Use in Nursing Home Flu Outbreaks May Cut Hospitalizations
In a real-world target trial emulation, starting oseltamivir prophylaxis within 2 days for at least 70% of eligible nursing home residents was linked to fewer hospitalizations, but not lower short-term mortality.

European ECLS End-of-Life Practices Vary Widely, Exposing Gaps in Ethics and Palliative Support
A large European survey found major regional and cultural differences in how clinicians approach ECLS withdrawal, with limited access to ethics and palliative care support in many institutions.

Difficulty Paying for Medical Care: Links to Psychological Distress and Healthcare Perceptions Among ICU Caregivers
More than half of ICU caregivers in a multicenter U.S. study reported difficulty paying for patient care, and financial strain was linked to higher posttraumatic stress, anxiety, depression, decisional regret, and medical mistrust.

Regional School-Based CPR Training With Low-Cost Manikin Delivered by School Nurses: The Home Multiplier Effect
A nurse-led school CPR program in Murcia, Spain, used low-cost manikins to train students and their families, creating a strong home-based multiplier effect and generally adequate basic life support performance.

Beyond Shared Identity: How Physician-Patient Racial Concordance Modulates Inpatient Advance Care Planning
A large-scale study of 390,000 hospitalizations reveals that while racial concordance modestly increases advance care planning (ACP) discussions, physician race and systemic quality initiatives play significant, nuanced roles in end-of-life

Nurse-Led Integrated Care Slashes Recurrence and Boosts Quality of Life After Atrial Fibrillation Ablation
The NURSECAT-AF trial demonstrates that structured nurse-led care significantly improves quality of life and reduces arrhythmia recurrence and emergency visits by 80% in patients undergoing their first catheter ablation for atrial fibrillat

Scaling Tobacco Cessation in HIV Care: National Quitlines as an Effective Alternative to Resource-Intensive Interventions
A landmark pragmatic randomized controlled trial in Vietnam reveals that proactive Quitline referrals are as effective as nurse-led counseling and nicotine replacement therapy for smoking cessation among people living with HIV, offering a s

Digital Imagery-Competing Task Intervention Significantly Reduces Intrusive Memories in Trauma-Exposed Healthcare Staff: Evidence from the GAINS-02 Bayesian Trial
A Bayesian adaptive randomized clinical trial reveals that a digital imagery-competing task intervention (ICTI) significantly reduces the frequency of intrusive memories and PTSD symptoms among healthcare workers exposed to pandemic-related

Giving Kids a Voice: How Patient-Reported Outcome Measures are Transforming Pediatric Specialty Care
Explore how standardized health questionnaires empower children and parents to share their priorities in medical settings, leading to more personalized and effective treatment plans.

Kangaroo Care Attenuates Pain and Systemic Inflammatory Markers During Retinopathy of Prematurity Screening
A randomized clinical trial demonstrates that Kangaroo care significantly reduces pain-related stress and systemic inflammatory responses in preterm infants undergoing retinopathy screening, suggesting a simple, non-pharmacological interven

Cumulative Geriatric Syndrome Burden: A Potent Predictor of 90-Day Mortality in Hospitalized Older Adults
A large multicenter cohort study demonstrates that the number of geriatric syndromes at hospital admission is independently and incrementally associated with 90-day mortality, suggesting that cumulative geriatric burden is a critical progno

Nurse-Led Education Program Effectively Reduces Treatment Delay in Patients with Diabetic High-Risk Foot: A Randomized Controlled Trial
This randomized controlled trial demonstrates that a structured nurse-led education intervention significantly improves foot care knowledge and self-efficacy while reducing both the intention and actual behavior of delaying treatment in pat

High-Dose Walking Booster Program: A Feasible Strategy to Overcome Rehabilitation Plateaus in Chronic Stroke
The Phase II HiWalk trial demonstrates that a 43-hour high-intensity walking booster program is safe and feasible for chronic stroke survivors, yielding significant walking speed improvements for individuals who have already completed their

Low-Intensity Motivational Intervention Shows Durable Benefits 5 Years After Stroke: Insights from the TaCAS Long-Term Follow-Up
The TaCAS long-term follow-up study reveals that a simple, conversation-based intervention can sustain improvements in physical health and independence for up to six years post-stroke, highlighting the lasting impact of patient-centered mot

Proactive ‘Caregiver Pathway’ Mitigates Long-Term PTSD and Anxiety in Families of ICU Survivors
A 12-month randomized controlled trial reveals that a structured nurse-led intervention, The Caregiver Pathway, significantly reduces symptoms of post-traumatic stress and anxiety among family caregivers of critically ill patients, particul

Germicidal UV Light and Respiratory Infections in Elderly Care: Insights from a Clinical Trial
A clinical trial assessing germicidal UV light in long-term care shows modest reduction in acute respiratory infections, suggesting UV technology as a supportive tool in infection control for older adults.

Offering Multiple Appropriate Alternatives Increases Primary Care Physicians’ Adoption of Recommended Care: A Randomized Trial
A randomized trial of 402 US primary care physicians found that presenting two or more appropriate treatment alternatives (vs one) increased clinicians’ likelihood of changing from a status quo plan to an evidence‑based alternative, especia

Intermediate Care Units Associated With Lower ICU Mortality and Better ICU Efficiency in Japan: Nationwide Cohort Analysis
A nationwide Japanese cohort study of 2.28 million ICU admissions finds that hospitals with intermediate care units (IMCUs) had modestly lower ICU and in-hospital mortality, fewer readmissions, shorter ICU stays, and higher ICU throughput w
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