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Public health officials in Medina County have detected an uptick in measles infections, confirming 18 total cases linked to a small cluster of familie
Russian public health authorities have launched an extensive epidemiological investigation and rolled out containment protocols following a suspected
A fresh outbreak of mpox has surfaced in Guinea-Bissau—the country's first recorded cases—bringing the viral infection back into the global spotlight.
Health authorities worldwide are monitoring the death of a 28-year-old laboratory worker in Siberia, Russia, following reports of an undetermined case
A large-scale UK cohort study found no strong associations between antibodies against multiple common infections and key Alzheimer’s disease neuropathologies, though possible interactions with APOE ε4 genotype and education warrant further
The RESOLVE trial demonstrates that 8 weeks of sofosbuvir-velpatasvir treatment is non-inferior to the standard 12-week regimen in treatment-naive, non-cirrhotic chronic hepatitis C patients, supporting shorter treatment duration without co
This study demonstrates that nucleos(t)ide analogue therapy significantly reduces cirrhosis and hepatocellular carcinoma risk in specific HBeAg-positive chronic HBV infection phases beyond current EASL 2025 treatment indications.
Pegylated interferon-alpha after nucleos(t)ide analog withdrawal induces coordinated expansion of regulatory B cells and contraction of HBV-specific T cells, impacting viral control and hepatic inflammation in HBeAg-negative chronic hepatit
A Phase 3b trial in eastern and southern Africa showed that long-acting injectable cabotegravir plus rilpivirine is noninferior to oral dolutegravir-based therapy for maintaining viral suppression in HIV patients facing adherence challenges
The LATA trial demonstrates that long-acting injectable cabotegravir-rilpivirine given every 8 weeks is superior to daily oral ART for maintaining virological suppression in adolescents with HIV in sub-Saharan Africa, with a favorable safet
The ENCORE trial demonstrates that amikacin liposome inhalation suspension combined with multidrug therapy improves respiratory symptoms and culture conversion in newly diagnosed Mycobacterium avium complex lung disease patients.
A multicenter study shows similar 14-day treatment failure rates among first-, second-, and third-generation oral cephalosporins for outpatient pyelonephritis, supporting flexibility in antibiotic choice post-ED discharge.
This review synthesizes evidence on how individual patient characteristics modify the comparative effects of cefepime versus piperacillin-tazobactam on acute kidney injury and neurologic outcomes in adults hospitalized with acute infection.
A large retrospective study shows no benefit of routine postoperative antibiotics after appendectomy for acute appendicitis, even with intra-abdominal fluid; highlights risk factors driving infections instead.
White blood cell count modifies mortality outcomes in sepsis patients treated with cefepime versus piperacillin-tazobactam, suggesting its potential role in guiding antibiotic selection.
An 8-week course of bemnifosbuvir and ruzasvir showed high sustained virologic response rates with excellent safety in treatment-naïve chronic hepatitis C patients across genotypes, including those with baseline resistance mutations.
This multicentre Italian study comparing clarithromycin and azithromycin for hospitalized infants with pertussis shows clarithromycin is linked to better clinical outcomes, including lower severity and fewer ICU admissions.
This phase 3 trial demonstrates that clesrovimab, a long-acting monoclonal antibody, is safe and well-tolerated in infants at risk for severe RSV disease across two consecutive RSV seasons, supporting its role in extended RSV prophylaxis.
This study elucidates the distinct clinical, pathological, and prognostic differences between native and allograft BK polyomavirus nephropathy, highlighting the severity and poorer outcomes associated with native-kidney BKPyVN and stressing
This study validates temperature-trajectory sepsis subphenotypes in a large Chinese ICU cohort, linking immune and coagulation dysfunction with mortality and highlighting differential responses to immunoglobulin therapy, particularly benefi
