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Dermatology

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Dermatology

High-Dose Oral Vitamin D for Management of Chemotherapy- and Radiation-Induced Skin Toxicity: A Multicenter Case Series

A retrospective series evaluating high-dose oral vitamin D demonstrated rapid improvement and symptom relief in patients with chemotherapy- and radiation-induced skin toxicity without adverse effects, supporting its potential role in oncode

Oct 2, 2026
Allergy & Immunology

Predicting Short-Term Outcomes in Pemphigus Patients Treated with Rituximab and Glucocorticoids: Insights from a Multicenter Chinese Cohort

This multicenter retrospective study identifies key baseline predictors influencing short-term remission and relapse in pemphigus patients treated with rituximab plus glucocorticoids, guiding personalized treatment strategies.

Oct 2, 2026
Dermatology

Systemic Therapies for Pediatric Moderate-to-Severe Atopic Dermatitis: Comparative Outcomes Across Skin Colors from the PEDISTAD Registry

This analysis of the 4-year PEDISTAD registry reveals dupilumab’s superior effectiveness and comparable safety in treating moderate-to-severe atopic dermatitis in children across diverse racial groups.

Oct 2, 2026
Dermatology

Distinct Pustular Psoriasis Flares After Biologic Withdrawal in Plaque Psoriasis: Clinical Features and Risk Factors

This multicenter study identifies a unique pustular psoriasis flare phenotype occurring after biologic therapy withdrawal in plaque psoriasis, detailing clinical characteristics and independent risk factors to guide vigilant monitoring and

Oct 2, 2026
Clinical Updates

Efficacy and Safety of Ruxolitinib Cream in Patients With Cutaneous Lichen Planus: A Randomized Clinical Trial Review

This review synthesizes current evidence on ruxolitinib 1.5% cream efficacy and safety in cutaneous lichen planus, highlighting significant lesion and pruritus reduction in a pivotal phase 2 RCT, supporting its potential as a novel topical

Oct 2, 2026
Dermatology

Unveiling Dupilumab-Associated Ocular Surface Disease in Atopic Dermatitis: Insights from a Large Prospective BioDay Cohort

This study reveals that 30.7% of atopic dermatitis patients treated with dupilumab develop ocular surface disease, despite prevalent ocular symptoms at baseline and increased ophthalmic treatment during therapy, linked to reduced conjunctiv

Sep 12, 2026Sign in to read
Dermatology

Cherry Angiomas as a Novel Vascular Manifestation in Neurofibromatosis Type 1: Epidemiology and Mechanistic Insights

Cherry angiomas are significantly more prevalent and occur at younger ages in individuals with Neurofibromatosis Type 1 (NF1), linked to biallelic NF1 inactivation in vascular cells. This discovery expands the vascular phenotype of NF1 and

Sep 3, 2026
Clinical Updates

Skin-Specific Outcomes of Brepocitinib in Dermatomyositis: Evidence from a Phase 3 Randomized Clinical Trial and Secondary Analysis

Brepocitinib, a selective TYK2-JAK1 inhibitor, showed rapid, sustained skin disease control, itch relief, and improved quality of life in dermatomyositis patients over 52 weeks with an acceptable safety profile in a global phase 3 trial.

Sep 3, 2026
Dermatology

A patient with CHILD syndrome mimicking Hailey-Hailey disease: A diagnostic challenge

We present a molecularly confirmed case of CHILD syndrome mimicking Hailey-Hailey disease without classical features, highlighting diagnostic pitfalls and benefits of targeted therapy.

Sep 3, 2026Sign in to read
Dermatology

Serum Amyloid A as a Prognostic Biomarker in Dermatomyositis-Associated Rapidly Progressive Interstitial Lung Disease

Elevated serum amyloid A correlates with rapidly progressive interstitial lung disease and mortality in dermatomyositis, with combined assessment alongside anti-MDA5 antibody improving risk stratification.

Sep 3, 2026
Dermatology

Rapid Isolation of Epidermal Stem Cells Enhances Single-Stage Composite Skin Graft Outcomes for Full-Thickness Wounds

Intraoperative isolation of autologous epidermal stem cells using Myseed technology improves vascularization, survival, and contraction rates of single-stage composite skin grafts in full-thickness wounds, offering a promising approach for

Sep 3, 2026Sign in to read
Dermatology

Equivalence of Online and In-Person Care in Managing Atopic Dermatitis: Insights from a Large Randomized Trial

A randomized clinical trial shows online team-based care is as effective as conventional in-person treatment for atopic dermatitis, offering an accessible alternative for chronic disease management.

Aug 26, 2026
Dermatology

Integrated 40-Gene Expression Profile Enhances Prognostic Precision and Guides Adjuvant Radiation in High-Risk Cutaneous Squamous Cell Carcinoma

The integrated 40-gene expression profile (i40-GEP) improves risk stratification in high-risk cutaneous squamous cell carcinoma, accurately predicting metastasis and local recurrence, and identifying patients who benefit most from adjuvant

Aug 26, 2026Sign in to read
Dermatology

Reversing Epigenetic Aging in Psoriasis: The Impact of Tildrakizumab over 52 Weeks

This study demonstrates that tildrakizumab, an IL-23 inhibitor, partially reverses accelerated epigenetic aging in psoriasis patients, highlighting a novel aspect of biologic therapy beyond skin inflammation control.

Aug 26, 2026
Clinical Updates

AI-Assisted Line-Field Confocal Optical Coherence Tomography for Early Detection of Subclinical Basal Cell Carcinoma: Current Evidence and Clinical Prospects

This review examines emerging evidence on AI-assisted LC-OCT as a noninvasive, accurate tool for detecting subclinical basal cell carcinoma in high-risk patients, highlighting diagnostic performance, subtype classification, and translationa

Aug 25, 2026Sign in to read
Clinical Updates

Early Respiratory Infection Burden and Atopic Dermatitis in Childhood: Insights from Prospective Birth Cohorts

Emerging evidence from prospective birth cohorts reveals a dose-dependent association between early respiratory infections and the risk of childhood atopic dermatitis, independent of genetic predisposition and antibiotic exposure.

Aug 20, 2026Sign in to read
Dermatology

Oral Dapsone in Refractory Rosacea: Defining a High Inflammatory Burden Subtype to Guide Precision Treatment

This exploratory study suggests oral dapsone benefits refractory rosacea patients, highlighting a ‘high inflammatory burden’ subtype that may predict treatment response, offering a framework for precision dermatologic care.

Aug 20, 2026
Allergy & Immunology

Upadacitinib for Severe Alopecia Areata in Adults and Adolescents: Evidence from Two Phase 3 UP-AA Randomized Clinical Trials

Two large phase 3 trials demonstrated that upadacitinib significantly improves hair regrowth and quality of life in severe alopecia areata among adolescents and adults, with a consistent and manageable safety profile.

Aug 17, 2026
Dermatology

Risk Stratification Models in Blood or Marrow Transplant Recipients for Predicting Cutaneous Malignant Neoplasms

Blood or marrow transplant recipients face an increased risk of skin cancers. This study develops validated risk models to identify high-risk patients for basal cell carcinoma, squamous cell carcinoma, and melanoma to optimize surveillance

Aug 16, 2026Sign in to read
Clinical Updates

Long-term Efficacy and Safety of Upadacitinib in Alopecia Areata: A Comprehensive Review of Real-World Evidence and Translational Insights

This review synthesizes current evidence on upadacitinib for alopecia areata, focusing on long-term efficacy, safety, and predictors of treatment response, highlighting the real-world retrospective study by Wang et al. alongside emerging cl

Aug 16, 2026
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