Section
This study evaluates the safety of sodium-glucose cotransporter 2 inhibitors (SGLT2is) versus DPP-4 inhibitors in adults aged 75 and older with type 2 diabetes, demonstrating favorable safety outcomes for SGLT2is without increased harm.
Combined measurement of LDL-C, lipoprotein(a), and hsCRP improves long-term prediction of atherosclerotic cardiovascular disease in a multiethnic cohort, highlighting important ethnic differences in absolute ASCVD risk.
This study compares 5-year postoperative outcomes of hip arthroscopy for femoroacetabular impingement in adolescents with borderline developmental dysplasia of the hip (BDDH) versus those without dysplasia, showing safety and efficacy with
This article reviews a study assessing fall risk in older adults through ReacStick-measured reaction time and inhibitory control, highlighting its superior precision over conventional tests and the protective role of knee extensor strength.
A retrospective analysis reveals that suspected cemental tears on periapical radiographs associate with significant localized periodontal bone loss, highlighting the need for combined clinical and radiographic diagnostics.
Tozorakimab, targeting interleukin-33, significantly reduces moderate to severe COPD exacerbations in former and current smokers despite standard inhaled therapy, offering a novel therapeutic approach with a favorable safety profile.
A novel RMR equation specific to elite cyclists improves energy expenditure estimation, supporting personalized nutrition and athletic performance optimization.
This study evaluates the safety and effectiveness of onabotulinumtoxinA doses above 400 units for upper and lower limb spasticity, showing no new safety concerns and suggesting clinical benefits.
This review synthesizes evidence from a large US network study on patient-reported postoperative dental pain, medication use, and functional interference, highlighting procedure-specific pain trajectories and opioid stewardship implications
A 9-year-old girl with atopic dermatitis and relapsing nephrotic syndrome achieved sustained remission of both conditions after dupilumab therapy, enabling withdrawal of steroids and tacrolimus.
New international recommendations position imaging as a context-driven adjunct in polymyalgia rheumatica (PMR): not routine for clear cases, most helpful in intermediate or atypical presentations, and not recommended for routine monitoring.
This multicenter retrospective study shows that GLP-1 receptor agonists improve glycemic control and cardiometabolic parameters with good tolerance in heart transplant recipients with type 2 diabetes, supporting their therapeutic role in th
This review synthesizes evidence on the characteristic clinical and histopathologic features of condyloma lata in secondary syphilis, emphasizing its reliable recognition to prevent misdiagnosis, especially at extragenital sites.
This study demonstrates that patient-specific virtual mirrored-image planning significantly improves symmetry, globe positioning, malar projection, and psychosocial outcomes compared to traditional intraoperative visual estimation in late r
This study examines differences in effect estimates between cluster-randomized and individually randomized clinical trials in prehospital, emergency, and critical care, revealing systematic bias in length-of-stay outcomes but not mortality.
Anticoagulation therapy in adults aged 80 and older with atrial fibrillation is linked to reduced all-cause mortality despite an increased risk of gastrointestinal bleeding, supporting its continued use in selected elderly patients.
Autoimmune neutropenia (AiN) in adults, though rare, is a chronic condition predominantly affecting women with autoimmune comorbidities. Treatment prioritizes observation, with therapies aimed at boosting neutrophil counts or modulating imm
This study reveals heterogeneous clinical phenotypes in mild-to-moderate COPD, demonstrating significant variability in exacerbation risk and lung function decline, emphasizing precision medicine for early intervention.
A randomized trial demonstrates that using an autologous anterior lens capsule as an intrascleral spacer during deep sclerectomy combined with phacoemulsification lowers intraocular pressure and enhances surgical success in glaucoma patient
This review synthesizes evidence establishing Days at Home within 90 days (DAH-90) after gastrointestinal cancer surgery as a valid, meaningful patient-centered outcome, integrating survival, morbidity, and healthcare utilization to optimiz
