Pathology & Lab Medicine/Bệnh học
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EN
MRD Does Not Consistently Predict PFS Across Modern CLL Trials: Why Surrogacy Depends on Therapy, Duration, and Sample Source
A large meta-analysis shows MRD strongly predicts outcomes for individual patients with CLL, but is an inconsistent trial-level surrogate for progression-free survival, particularly with BTK inhibitor and venetoclax-based regimens.
Pathology & Lab Medicine/Bệnh họcMay 4, 2026

EN
Urinary Free Cortisol Thresholds Sharpen the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome
A Spanish multicenter validation study shows that urinary free cortisol expressed as multiples of the upper limit of normal can meaningfully stratify the likelihood of ectopic ACTH secretion versus Cushing’s disease.
Pathology & Lab Medicine/Bệnh họcMay 4, 2026
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