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Prominent V Waves in Heart Failure with Preserved Ejection Fraction: Unveiling Their Impact on Right Ventricular Afterload and Pulmonary Vascular Assessment
Cardiologyright ventricular afterloadheart failure

Prominent V Waves in Heart Failure with Preserved Ejection Fraction: Unveiling Their Impact on Right Ventricular Afterload and Pulmonary Vascular Assessment

By MedXY|Oct 17, 2026

Prominent left atrial V waves in heart failure with preserved ejection fraction significantly increase right ventricular afterload independent of pulmonary vascular disease, challenging current hemodynamic assessments and impacting patient

Sotatercept as Add-On Therapy in Pediatric Pulmonary Hypertension: Promising Outcomes from the Pediatric Pulmonary Hypertension Network
Cardiology
Huyết Áp Phổi
pediatric cardiology

Sotatercept as Add-On Therapy in Pediatric Pulmonary Hypertension: Promising Outcomes from the Pediatric Pulmonary Hypertension Network

By MedXY|Oct 11, 2026

Retrospective multi-center data demonstrate that sotatercept improves functional status, exercise capacity, and hemodynamics in children with pulmonary hypertension, with a manageable safety profile.

Pulmonary Artery Dilation as a Mark of Pulmonary Hypertension in Chronic Lung Disease: Insights from the PVDOMICS Cohort
CardiologyChest CTHuyết Áp Phổi

Pulmonary Artery Dilation as a Mark of Pulmonary Hypertension in Chronic Lung Disease: Insights from the PVDOMICS Cohort

By MedXY|Sep 29, 2026

Pulmonary artery dilation on chest CT correlates with pulmonary hypertension across chronic lung diseases, with diagnostic accuracy varying by disease subtype.

Refining Right Ventricular Assessment in Pulmonary Hypertension: Impact of Postprocessing Techniques on Cardiac MRI Metrics
CardiologyCardiac Magnetic ResonanceHuyết Áp Phổi

Refining Right Ventricular Assessment in Pulmonary Hypertension: Impact of Postprocessing Techniques on Cardiac MRI Metrics

By MedXY|Sep 17, 2026

This study examines how cardiac MRI postprocessing methods, including trabeculation exclusion and pulmonary artery flow measurement sites, significantly influence right ventricular volume and function assessment in pulmonary hypertension pa

Distinct Lipid Metabolic Profiles Unveil Pathophysiological Differences Between Postcapillary and Combined Pre- and Postcapillary Pulmonary Hypertension
CardiologyHuyết Áp Phổioxylipins

Distinct Lipid Metabolic Profiles Unveil Pathophysiological Differences Between Postcapillary and Combined Pre- and Postcapillary Pulmonary Hypertension

By MedXY|Sep 14, 2026

This study reveals unique fatty acid and oxylipin metabolic signatures that differentiate isolated postcapillary pulmonary hypertension from combined pre- and postcapillary PH, highlighting potential biomarkers and therapeutic targets.

Unveiling PUS7’s Role in Pulmonary Hypertension: A Novel Epigenetic Driver of Vascular Remodeling
CardiologyHuyết Áp PhổiPseudouridylation

Unveiling PUS7’s Role in Pulmonary Hypertension: A Novel Epigenetic Driver of Vascular Remodeling

By MedXY|Sep 4, 2026

This article explores how PUS7-induced pseudouridylation of TGFBI mRNA promotes pulmonary hypertension via epigenetic regulation, revealing promising new therapeutic targets.

Validating the Venous Excess Ultrasound Score (VExUS) for Right Atrial Pressure Assessment in Pulmonary Hypertension: A Multicenter Study
CardiologyHuyết Áp PhổiRight Heart Catheterization

Validating the Venous Excess Ultrasound Score (VExUS) for Right Atrial Pressure Assessment in Pulmonary Hypertension: A Multicenter Study

By MedXY|Sep 2, 2026

This multicenter study validates the Venous Excess Ultrasound Score (VExUS) as a highly accurate, noninvasive tool to predict right atrial pressure in patients evaluated for pulmonary hypertension, outperforming isolated echocardiographic m

Pulmonary Artery Stiffness and Right Ventricular Function: A Superior Predictor of Mortality in Mild Pulmonary Hypertension
CardiologyHuyết Áp Phổimortality prediction

Pulmonary Artery Stiffness and Right Ventricular Function: A Superior Predictor of Mortality in Mild Pulmonary Hypertension

By MedXY|Aug 27, 2026

This study reveals that pulmonary artery stiffness and right ventricular function parameters independently predict mortality better than pulmonary vascular resistance in mild pulmonary hypertension, supporting their role in early disease ri

Unraveling Right Ventricular Failure in PH-HFpEF: Integrative Insights from Vascular Mechanics and Transcriptomics
CardiologyHuyết Áp PhổiRight Ventricular Failure

Unraveling Right Ventricular Failure in PH-HFpEF: Integrative Insights from Vascular Mechanics and Transcriptomics

By MedXY|Aug 24, 2026

This study integrates vascular mechanics, advanced imaging, and myocardial transcriptomics to elucidate the mechanisms of right ventricular failure in pulmonary hypertension secondary to heart failure with preserved ejection fraction, uncov

Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling
CardiologyBACH1Huyết Áp Phổi

Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling

By MedXY|Jul 15, 2026

BACH1 stabilization under hypoxia promotes pulmonary hypertension by enhancing TGFBR2/SMAD pathway activity in pulmonary artery smooth muscle cells, suggesting BACH1 as a promising therapeutic target for PH.

Impact of Short-Term High-Altitude Exposure on Right Ventricular Load and Oxygen Delivery in Pulmonary Vascular Disease Patients
Cardiologyhigh altitudeHuyết Áp Phổi

Impact of Short-Term High-Altitude Exposure on Right Ventricular Load and Oxygen Delivery in Pulmonary Vascular Disease Patients

By MedXY|Jul 5, 2026

A two-day stay at 2500 m altitude increases right ventricular afterload and impairs ventricular-arterial coupling but maintains oxygen delivery in stable pulmonary vascular disease patients.

Unveiling the Phenotype of Unclassified Pulmonary Hypertension: A Hidden Spectrum of Early Heart Failure with Preserved Ejection Fraction
CardiologyHFpEFHuyết Áp Phổi

Unveiling the Phenotype of Unclassified Pulmonary Hypertension: A Hidden Spectrum of Early Heart Failure with Preserved Ejection Fraction

By MedXY|Jun 20, 2026

Unclassified pulmonary hypertension often reflects early-stage HFpEF linked to left heart and metabolic dysfunction, identifiable via dynamic right heart catheterization and metabolomics.

CT Small-Artery Loss Tracks Severe Pulmonary Hypertension in COPD and Fibrosing ILD More Closely Than Parenchymal Damage
newsComputed tomographyCOPD

CT Small-Artery Loss Tracks Severe Pulmonary Hypertension in COPD and Fibrosing ILD More Closely Than Parenchymal Damage

By MedXY|Jun 2, 2026

CT-derived pulmonary vascular metrics, especially the small-artery to total arterial volume ratio, identify severe pulmonary hypertension in chronic lung disease, with distinct vascular remodeling patterns in COPD and fibrosing ILD.

Dual versus monotherapy pretreatment before balloon pulmonary angioplasty in CTEPH: effects on complications and outcomes
CardiologyBalloon pulmonary angioplastyCTEPH

Dual versus monotherapy pretreatment before balloon pulmonary angioplasty in CTEPH: effects on complications and outcomes

By MedXY|May 18, 2026

In CTEPH patients undergoing balloon pulmonary angioplasty, dual pulmonary hypertension-targeted pretreatment was linked to fewer thoracic complications and better 6-month clinical improvement than monotherapy.

The BMPR2 Nexus: How Breast Cancer Acts as a Second Hit for Pulmonary Hypertension
CardiologyBMPR2breast cancer

The BMPR2 Nexus: How Breast Cancer Acts as a Second Hit for Pulmonary Hypertension

By MedXY|Mar 1, 2026

Emerging evidence identifies a bidirectional link between breast cancer and pulmonary arterial hypertension (PAH) driven by BMPR2 signaling and IL-1β-mediated inflammation. This study suggests breast cancer may serve as a critical second hi

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