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Postoperative Atrial Fibrillation After Cardiac Surgery: Common, Variably Treated, and Linked to Worse 1-Year Outcomes

Postoperative Atrial Fibrillation After Cardiac Surgery: Common, Variably Treated, and Linked to Worse 1-Year Outcomes

The VISION Cardiac Surgery cohort found POAF in about one-third of patients, with wide variation in discharge treatment. POAF strongly predicted later atrial fibrillation and was associated with higher 1-year mortality.

Section: CardiologyJun 20, 2026

Exploring the Impact of Body Mass Index on Heart Failure Outcomes: Insights from Mendelian Randomization

Exploring the Impact of Body Mass Index on Heart Failure Outcomes: Insights from Mendelian Randomization

This study leverages Mendelian randomization to demonstrate that genetically elevated BMI is associated with increased mortality and adverse cardiovascular outcomes in heart failure, irrespective of ejection fraction status, underscoring po

Section: CardiologyJun 10, 2026

Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study

Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study

This study uses Mendelian randomization to show that higher genetically predicted BMI is associated with increased all-cause mortality and cardiovascular events in heart failure patients, regardless of ejection fraction status.

Section: CardiologyJun 10, 2026

Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts

Higher Interleukin-6 Levels Predict Broad Cardiovascular Risk and Mortality Across Diverse Cohorts

A pooled analysis of 59,396 participants found that higher serum IL-6 concentrations independently predicted nine cardiovascular and mortality outcomes, with consistent associations across key clinical subgroups.

Section: CardiologyMay 31, 2026

Health Plan Disenrollment and Mortality After Starting Medications for Opioid Use Disorder

Health Plan Disenrollment and Mortality After Starting Medications for Opioid Use Disorder

A large cohort study found that health plan disenrollment after starting buprenorphine or naltrexone for opioid use disorder was linked to higher all-cause and overdose mortality, highlighting the importance of continuous coverage and treat

Section: newsMay 23, 2026

Outcomes of Heart Failure With Reduced, Mildly Reduced, or Preserved Ejection Fraction: ESC HF III Registry

Outcomes of Heart Failure With Reduced, Mildly Reduced, or Preserved Ejection Fraction: ESC HF III Registry

The ESC HF III Registry found substantial mortality and rehospitalization across heart failure phenotypes. Risk was highest after acute hospitalization and generally worse with reduced ejection fraction, but HFmrEF and HFpEF also carried si

Section: CardiologyMay 19, 2026

Long-Term SAFE-PAD Data Reassure on Mortality After Paclitaxel-Coated Femoropopliteal Interventions

Long-Term SAFE-PAD Data Reassure on Mortality After Paclitaxel-Coated Femoropopliteal Interventions

In Medicare patients undergoing femoropopliteal revascularization, drug-coated devices were not associated with higher long-term mortality, supporting the safety of paclitaxel-coated technology after years of regulatory concern.

Section: CardiologyMay 6, 2026

Antifungal Therapy Slashes Mortality in COVID-19-Associated Pulmonary Aspergillosis: European Data Confirms

Antifungal Therapy Slashes Mortality in COVID-19-Associated Pulmonary Aspergillosis: European Data Confirms

A multicenter European cohort study demonstrates that antifungal treatment significantly reduces 60-day mortality in COVID-19-associated pulmonary aspergillosis (CAPA), particularly in immunocompromised patients. Key findings underscore the

Section: Critical CareApr 24, 2026

Higher EMS Clinician Trauma Volume Linked to Lower Early Mortality in Trauma Patients

Higher EMS Clinician Trauma Volume Linked to Lower Early Mortality in Trauma Patients

A study finds that increased annual trauma patient volume per EMS clinician is associated with significantly reduced 6-hour and in-hospital mortality rates, highlighting the importance of experience in prehospital trauma care.

Section: Critical CareApr 23, 2026

Delayed Surgery in Bowel Obstruction: A Hidden Driver of Mortality and Recurrence in France

Delayed Surgery in Bowel Obstruction: A Hidden Driver of Mortality and Recurrence in France

A nationwide French study reveals that surgical delay beyond 9 days triples early mortality risk compared to immediate surgery. While non-operative management carries higher long-term recurrence, timely laparoscopic intervention offers the

Section: GastroenterologyApr 14, 2026

SGLT2 Inhibitors Do Not Increase Amputation Risk in Diabetic Foot Ulcer: Study Reveals Significant Mortality Benefit

SGLT2 Inhibitors Do Not Increase Amputation Risk in Diabetic Foot Ulcer: Study Reveals Significant Mortality Benefit

A retrospective study of 452 diabetic foot ulcer patients found that SGLT2 inhibitor use was not associated with increased amputation risk at 1 year and was linked to significantly lower mortality (1.1% vs 9.2%) and faster wound healing (44

Section: Diabetes & EndocrinologyApr 7, 2026

High-Volume EMS Clinicians Save More Lives: The Critical Link Between Experience and Trauma Survival

High-Volume EMS Clinicians Save More Lives: The Critical Link Between Experience and Trauma Survival

A study of over 6,000 patient interactions reveals that higher annual trauma volumes per EMS clinician are significantly associated with reduced 6-hour and in-hospital mortality, emphasizing the need for volume-based staffing and training.

Section: Emergency MedicineFeb 20, 2026

Unpacking the ‘Weathering’ Hypothesis: How Cumulative Lifespan Stress and Inflammation Drive Racial Disparities in Mortality

Unpacking the ‘Weathering’ Hypothesis: How Cumulative Lifespan Stress and Inflammation Drive Racial Disparities in Mortality

A longitudinal study identifies that cumulative lifetime stress and systemic inflammation mediate nearly 50% of the mortality gap between Black and White adults, providing a biological link between structural inequity and premature death.

Section: newsFeb 10, 2026

The Rising Burden of Sarcoidosis in England: New Evidence of Increasing Incidence and Significant Mortality Gaps

The Rising Burden of Sarcoidosis in England: New Evidence of Increasing Incidence and Significant Mortality Gaps

A landmark study of over 18,000 patients reveals that sarcoidosis incidence and prevalence in England are rising, particularly among older adults. With a 36% higher mortality risk compared to the general population, these findings demand a

Section: newsJan 8, 2026

Higher Hospital-Level Utilization of Continuous Kidney Replacement Therapy Associated with Reduced Mortality in Critically Ill Patients

Higher Hospital-Level Utilization of Continuous Kidney Replacement Therapy Associated with Reduced Mortality in Critically Ill Patients

A large-scale multicenter study reveals that hospitals with higher utilization rates of continuous kidney replacement therapy (CKRT) achieve significantly lower 90-day mortality for critically ill AKI patients compared to low-utilization ce

Section: Critical CareDec 31, 2025

Early Enteral Nutrition in Critically Ill Children: Promising Associations but Very Low Certainty — What Clinicians Should Know

Early Enteral Nutrition in Critically Ill Children: Promising Associations but Very Low Certainty — What Clinicians Should Know

A systematic review and meta-analysis found early enteral nutrition (EEN) in critically ill children associated with lower mortality (adjusted OR 0.36) and improvements in several clinical outcomes, but evidence certainty is very low due to

Section: Critical CareDec 14, 2025

Fewer Post‑Traumatic ARDS Cases but Rising Mortality: A 2007–2019 NTDB Cohort Analysis

Fewer Post‑Traumatic ARDS Cases but Rising Mortality: A 2007–2019 NTDB Cohort Analysis

A 2007–2019 National Trauma Data Bank analysis found ARDS incidence among ventilated trauma patients fell substantially, yet ARDS remained independently associated with increased 30‑day mortality and crude ARDS mortality rose to nearly 30%.

Section: Critical CareDec 9, 2025

Unequal and Multisystem Mortality Risks After Tropical Cyclones: Renal, Injury, Infectious and Chronic Disease Burdens Across Nine Countries

Unequal and Multisystem Mortality Risks After Tropical Cyclones: Renal, Injury, Infectious and Chronic Disease Burdens Across Nine Countries

A multinational time-series study across nine countries found increased short-term mortality after tropical cyclones for multiple causes — highest for renal disease and injuries — with larger effects in deprived and cyclone-naïve communitie

Section: NephrologyNov 22, 2025

The Vanishing Female Survival Advantage in Stage 5 CKD: Higher Mortality and Lower Receipt of Kidney Replacement Therapy Among Women

The Vanishing Female Survival Advantage in Stage 5 CKD: Higher Mortality and Lower Receipt of Kidney Replacement Therapy Among Women

In a population-based Alberta cohort, women with incident stage 5 CKD lost the usual female survival advantage: younger women had substantially higher excess mortality than men and were less likely to receive transplants or dialysis, indepe

Section: Internal MedicineNov 18, 2025

Metformin Exposure Associated with Up to 81% Lower 30‑Day Mortality After Cardiac Surgery in T2DM: A Critical Appraisal of AHA 2025 MIMIC‑IV Cohort Findings

Metformin Exposure Associated with Up to 81% Lower 30‑Day Mortality After Cardiac Surgery in T2DM: A Critical Appraisal of AHA 2025 MIMIC‑IV Cohort Findings

A retrospective MIMIC‑IV cohort presented at AHA 2025 found perioperative metformin exposure in T2DM patients undergoing cardiac surgery associated with markedly lower 30‑, 90‑ and 360‑day mortality. Results are compelling but observational

Section: CardiologyNov 14, 2025

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