Hypertension

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Global Disparities in Heart Failure: Incidence and Mortality Across Income Levels and Regions

The PURE study reveals significant global disparities in heart failure incidence and mortality, with hypertension as the leading modifiable risk factor, highlighting the need for targeted prevention and treatment strategies.

Section: CardiologyApr 28, 2026

Shear Stress-Induced Endothelial HEG1 Signalling: A Novel Pathway Linking Blood Flow to Blood Pressure Regulation

Researchers identify HEG1 as a critical flow-sensitive endothelial protein that regulates blood pressure through CUL3-mediated degradation of PHACTR1, linking reduced shear stress in hypertension to impaired NO production and vascular dysfu

Hypertension

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Global Disparities in Heart Failure: Incidence and Mortality Across Income Levels and Regions

Shear Stress-Induced Endothelial HEG1 Signalling: A Novel Pathway Linking Blood Flow to Blood Pressure Regulation

Even ‘Elevated’ Blood Pressure Raises Dementia Risk: Insights from 2.8 Million Adults Over 8 Years

Why Exercise Blood Pressure Alone May Miss Cardiovascular Risk—and What Combining It With Fitness Reveals

Mobile Health Intervention Achieves 24% Better Blood Pressure Control in Stroke Survivors: PINGS Trial Results from Ghana

Redefining the Renin-Aldosterone Axis: From Categorical Diagnosis to a Continuous Spectrum of Cardiorenal Risk

Deciphering the Clinician’s Dilemma: Determinants of Antihypertensive Treatment Intensification in Older Adults

Patient Engagement and the Reality of Home Blood Pressure Monitoring: New Research Perspectives

Relacorilant Demonstrates Sustained Efficacy in Hypertension Control for Patients with Cushing’s Syndrome: Results from the Phase 3 GRACE Study

Beyond the Binary: The Evolving Consensus on the Spectrum of Primary Aldosteronism and Cardiovascular Risk

Oxygen-Guided Success: A New Frontier in Adrenal Venous Sampling for Primary Aldosteronism

Mechanistic Insights into APOL1-Mediated Hypertension: The STING-Endothelin 1 Axis as a Therapeutic Target

Intensive Blood Pressure Targets Below 130/80 mmHg Benefit Patients Across the Cardiovascular-Kidney-Metabolic Syndrome Spectrum

Early Life Origins of Hypertension: Longitudinal Evidence That Blood Pressure Tracks from Birth to School Age

Beyond Weight Loss: CagriSema Emerges as a Potent Antihypertensive in Obesity Management

Despite Free Devices and Personalized Support, One-Third of Patients Fail to Engage with Home Blood Pressure Monitoring

NT-proBNP-Defined Heart Stress: A New Compass for Individualized Blood Pressure Targets in Older Adults?

Prediabetes and Silent Cardiac Injury: A High-Risk Synergy for Heart Failure in Hypertensive Patients

Intensive Blood Pressure Control to <120 mmHg: Holistic Benefits Across Frailty, Quality of Life, and Microvascular Health in the ESPRIT Trial